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  • Deals

Details:

The acquisition supplements BioVaxys' existing cancer vaccine portfolio with the addition of DPX-Survivac (maveropepimut-S), a DPX™-formulated cancer vaccine that delivers antigenic peptides from survivin, a cancer antigen commonly overexpressed in advanced cancers.


Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Biovaxys

Deal Size: $25.7 million Upfront Cash: $25.7 million

Deal Type: Acquisition February 12, 2024

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  • Development Update

Details:

IMV’s lead candidate, DPX-Survivac (maveropepimut-S), delivers antigenic peptides from survivin, a well-recognized cancer antigen commonly overexpressed in advanced cancers.


Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable February 13, 2023

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  • Development Update

Details:

IMV’s lead candidate, DPX-Survivac (maveropepimut-S), delivers antigenic peptides from survivin, a well-recognized cancer antigen commonly overexpressed in advanced cancers.


Lead Product(s): Maveropepimut-S,Pembrolizumab

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable January 08, 2023

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  • Deals

Details:

DPX-Survivac (maveropepimut-S) is a novel T cell immunotherapy that uses the DPX platform to elicit strong and sustained survivin-specific T cell responses against tumor cells.


Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

Deal Size: $9.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering December 20, 2022

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  • Deals

Details:

DPX-Survivac (maveropepimut-S) is a novel T cell immunotherapy that uses the DPX platform to elicit strong and sustained survivin-specific T cell responses against tumor cells.


Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: H.C. Wainwright & Co.

Deal Size: $9.0 million Upfront Cash: Undisclosed

Deal Type: Public Offering December 16, 2022

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  • Development Update

Details:

IMV’s lead candidate, DPX-Survivac (maveropepimut-S, MVP-S), delivers antigenic peptides from survivin, a well-recognized cancer antigen commonly overexpressed in advanced cancers.


Lead Product(s): Maveropepimut-S,Pembrolizumab

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable December 15, 2022

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  • Development Update

Details:

Maveropepimut-S (DPX-Survivac) Generating Cancer-Targeted Killer T Cells combines advantages of DPX platform and cancer antigen survivin, is lead candidate of IMV’s new class of immunotherapies that generates cancer-targeted T cells in vivo.


Lead Product(s): Maveropepimut-S,Cyclophosphamide

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 28, 2022

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  • Development Update

Details:

Combination of DPX-Survivac (maveropepimut-s) and pembrolizumab showed encouraging clinical activity in advanced, metastatic bladder cancer patients, particularly in patients who had received prior immune checkpoint inhibitor therapy.


Lead Product(s): Maveropepimut-S,Pembrolizumab,Cyclophosphamide

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Large molecule

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable April 08, 2022

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  • Development Update

Details:

DPX-Survivac, a novel T cell immunotherapy that uses the DPX platform to elicit a coordinated anti-tumor immune response involving natural killer cells in both translational and preclinical studies.


Lead Product(s): Maveropepimut-S,Cyclophosphamide

Therapeutic Area: Oncology Product Name: DPX-Survivac

Highest Development Status: Phase IIProduct Type: Vaccine

Partner/Sponsor/Collaborator: Not Applicable

Deal Size: Not Applicable Upfront Cash: Not Applicable

Deal Type: Not Applicable March 09, 2022

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