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Chemistry

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Also known as: 543906-09-8, Afq056, Afq-056, (3ar,4s,7ar)-octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1h-indole-1-carboxylic acid methyl ester, Gt0i9sv4f6, Methyl (3ar,4s,7ar)-4-hydroxy-4-(m-tolylethynyl)octahydro-1h-indole-1-carboxylate
Molecular Formula
C19H23NO3
Molecular Weight
313.4  g/mol
InChI Key
ZFPZEYHRWGMJCV-ZHALLVOQSA-N
FDA UNII
GT0I9SV4F6

Mavoglurant
Mavoglurant has been used in trials studying the treatment of Patient Diagnosed With OCD and and Resistant to SSRI Treatment (Failed SSRI Over 12 Weeks at Appropriate Doses).
1 2D Structure

Mavoglurant

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
methyl (3aR,4S,7aR)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-3,3a,5,6,7,7a-hexahydro-2H-indole-1-carboxylate
2.1.2 InChI
InChI=1S/C19H23NO3/c1-14-5-3-6-15(13-14)8-11-19(22)10-4-7-17-16(19)9-12-20(17)18(21)23-2/h3,5-6,13,16-17,22H,4,7,9-10,12H2,1-2H3/t16-,17-,19-/m1/s1
2.1.3 InChI Key
ZFPZEYHRWGMJCV-ZHALLVOQSA-N
2.1.4 Canonical SMILES
CC1=CC(=CC=C1)C#CC2(CCCC3C2CCN3C(=O)OC)O
2.1.5 Isomeric SMILES
CC1=CC(=CC=C1)C#C[C@@]2(CCC[C@@H]3[C@H]2CCN3C(=O)OC)O
2.2 Other Identifiers
2.2.1 UNII
GT0I9SV4F6
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Afq056

2.3.2 Depositor-Supplied Synonyms

1. 543906-09-8

2. Afq056

3. Afq-056

4. (3ar,4s,7ar)-octahydro-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-1h-indole-1-carboxylic Acid Methyl Ester

5. Gt0i9sv4f6

6. Methyl (3ar,4s,7ar)-4-hydroxy-4-(m-tolylethynyl)octahydro-1h-indole-1-carboxylate

7. 1h-indole-1-carboxylic Acid, Octahydro-4-hydroxy-4-(2-(3-methylphenyl)ethynyl)-, Methyl Ester, (3ar,4s,7ar)-

8. Methyl (3ar,4s,7ar)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]-3,3a,5,6,7,7a-hexahydro-2h-indole-1-carboxylate

9. (-)-(3ar,4s,7ar)-4-hydroxy-4-m-tolylethynyl-octahydro-indole-1-carboxylic Acid Methyl Ester

10. Mavoglurant [inn]

11. Mavoglurant [usan:inn]

12. Unii-gt0i9sv4f6

13. Afq 056

14. 4oo9

15. Mavoglurant, Afq056

16. Mavoglurant [usan]

17. Mavoglurant [who-dd]

18. Schembl989279

19. Gtpl7586

20. Chembl3087515

21. Dtxsid30202777

22. Bcp20624

23. Ex-a1564

24. Zinc3817189

25. Bdbm50443085

26. Cs-5245

27. Db13004

28. As-79009

29. Hy-15257

30. Db-102250

31. Q6589598

32. (3ar,4s,7ar)-methyl 4-hydroxy-4-(m-tolylethynyl)octahydro-1h-indole-1-carboxylate

33. Methyl (3ar,4s,7ar)-4-hydroxy-4-[(3-methylphenyl)ethynyl]octahydro-1h-indole-1-carboxylate

34. 1h-indole-1-carboxylic Acid, Octahydro-4-hydroxy-4-((3-methylphenyl)ethynyl)-, Methyl Ester, (3ar,4s,7ar)-

35. 2u8

36. Methyl (3ar,4s,7ar)-4-hydroxy-4-[2-(3-methylphenyl)ethynyl]octahydro-1h-indole-1-carboxylate

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 313.4 g/mol
Molecular Formula C19H23NO3
XLogP32.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count3
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area49.8
Heavy Atom Count23
Formal Charge0
Complexity519
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Mavoglurant Manufacturers

A Mavoglurant manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mavoglurant, including repackagers and relabelers. The FDA regulates Mavoglurant manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mavoglurant API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Mavoglurant Suppliers

A Mavoglurant supplier is an individual or a company that provides Mavoglurant active pharmaceutical ingredient (API) or Mavoglurant finished formulations upon request. The Mavoglurant suppliers may include Mavoglurant API manufacturers, exporters, distributors and traders.

Mavoglurant GMP

Mavoglurant Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Mavoglurant GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mavoglurant GMP manufacturer or Mavoglurant GMP API supplier for your needs.

Mavoglurant CoA

A Mavoglurant CoA (Certificate of Analysis) is a formal document that attests to Mavoglurant's compliance with Mavoglurant specifications and serves as a tool for batch-level quality control.

Mavoglurant CoA mostly includes findings from lab analyses of a specific batch. For each Mavoglurant CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Mavoglurant may be tested according to a variety of international standards, such as European Pharmacopoeia (Mavoglurant EP), Mavoglurant JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mavoglurant USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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