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    Chemistry

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    Also known as: Diprolene, Diprosone, 5593-20-4, Maxivate, Diprolene af, Alphatrex
    Molecular Formula
    C28H37FO7
    Molecular Weight
    504.6  g/mol
    InChI Key
    CIWBQSYVNNPZIQ-XYWKZLDCSA-N
    FDA UNII
    826Y60901U
    Betamethasone Dipropionate
    Betamethasone Dipropionate is the 17,21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.
    1 2D Structure

    Betamethasone Dipropionate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate
    2.1.2 InChI
    InChI=1S/C28H37FO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
    2.1.3 InChI Key
    CIWBQSYVNNPZIQ-XYWKZLDCSA-N
    2.1.4 Canonical SMILES
    CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)OC(=O)CC
    2.1.5 Isomeric SMILES
    CCC(=O)OCC(=O)[C@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)OC(=O)CC
    2.2 Other Identifiers
    2.2.1 UNII
    826Y60901U
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Augmented Betamethasone Dipropionate

    2. Beloderm

    3. Betamethasone Propionate

    4. Betamethasone-17,21-dipropionate

    5. Diprolene

    6. Diprosone

    7. Maxivate

    2.3.2 Depositor-Supplied Synonyms

    1. Diprolene

    2. Diprosone

    3. 5593-20-4

    4. Maxivate

    5. Diprolene Af

    6. Alphatrex

    7. Diproderm

    8. Psorion

    9. Betamethasone 17,21-dipropionate

    10. Rinderon Dp

    11. Diprosis

    12. Diprospan

    13. Sch 11460

    14. Sch-11460

    15. S-3440

    16. Betamethasone (as Dipropionate)

    17. Betamethasone-17,21-dipropionate

    18. Chebi:31276

    19. Nsc-758415

    20. Pregna-1,4-diene-3,20-dione,9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11b,16b)-

    21. Beta-methasone 17,21-dipropionate

    22. 826y60901u

    23. [2-[(8s,9r,10s,11s,13s,14s,16s,17r)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] Propanoate

    24. (11-beta,16-beta)-9-chloro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione

    25. 9-fluoro-11beta-hydroxy-16beta-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl Dipropanoate

    26. 9-fluoro-11.beta.,17,21-trihydroxy-16.beta.-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

    27. 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione-17,21-dipropionate

    28. Einecs 227-005-2

    29. Brn 3638108

    30. .beta.-methasone 17,21-dipropionate

    31. Betamethasone Dipropionate (diprolene)

    32. S 3440

    33. Diprolene (tn)

    34. Unii-826y60901u

    35. Ncgc00159360-02

    36. Ncgc00159443-02

    37. Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11.beta.,16.beta.)-

    38. Sernivo (tn)

    39. Rinderon-dp (tn)

    40. Betamethasone Dipropionate [usan:usp:jan]

    41. Betamethasone-dipropionate

    42. Dsstox_cid_2672

    43. Betamethasone Diprop

    44. Schembl7519

    45. 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

    46. Dsstox_rid_76683

    47. Dsstox_gsid_22672

    48. 9-fluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-di(propionate)

    49. Betamethasone-17,21-dipropionate 100 Microg/ml In Acetonitrile

    50. Chembl1200384

    51. Dtxsid2022672

    52. Component Of Betasone (salt/mix)

    53. Component Of Alphatrex (salt/mix)

    54. Amy22130

    55. Zinc4212137

    56. Tox21_113343

    57. Bdbm50421892

    58. S1688

    59. Akos015969733

    60. Betamethasone Dipropionate (jp17/usp)

    61. Ccg-269732

    62. Cs-7549

    63. Ks-5303

    64. Nsc 758415

    65. Betamethasone Dipropionate [jan]

    66. Betamethasone Dipropionate [usan]

    67. Ncgc00159443-01

    68. Ncgc00159443-05

    69. (11beta,16beta)-9-fluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl Dipropanoate

    70. 2-((2s,10s,11s,13s,15s,17s,1r,14r)-1-fluoro-17-hydroxy-2,13,15-trimethyl-5-oxo -14-propanoyloxytetracyclo[8.7.0.0<2,7>.0<11,15>]heptadeca-3,6-dien-14-yl)-2-o Xoethyl Propanoate

    71. Betamethasone Dipropionate [mart.]

    72. Betamethasone Dipropionate [vandf]

    73. Hy-13571

    74. Pregna-1,4-diene-3,20-dione, 9-fluoro-11-beta,17,21-trihydroxy-16-beta-methyl-, 17,21-dipropionate

    75. Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16beta)

    76. Betamethasone Dipropionate [usp-rs]

    77. Betamethasone Dipropionate [who-dd]

    78. Cas-5593-20-4

    79. Betamethasone Dipropionate, Augmented

    80. B3166

    81. Betamethasone 17,21-dipropionate [mi]

    82. Betamethasone Dipropionate [green Book]

    83. Betamethasone Dipropionate [orange Book]

    84. D01637

    85. Ab01274713-01

    86. Ab01274713_02

    87. Betamethasone 17.alpha.,21-dipropionate

    88. Betamethasone Dipropionate [ep Monograph]

    89. Betamethasone Dipropionate [usp Monograph]

    90. Wynzora Component Betamethasone Dipropionate

    91. Enstilar Component Betamethasone Dipropionate

    92. Lotrisone Component Betamethasone Dipropionate

    93. Q4897349

    94. Taclonex Component Betamethasone Dipropionate

    95. Betamethasone Dipropionate Component Of Enstilar

    96. Betamethasone Dipropionate Component Of Taclonex

    97. Betamethasone Dipropionate Component Of Wynzora

    98. Brd-k58148589-001-03-6

    99. Leo-90100 Component Betamethasone Dipropionate

    100. Betamethasone Dipropionate Component Of Lotrisone

    101. Betamethasone Dipropionate Component Of Leo-90100

    102. Betamethasone-17,21-dipropionate 100 Microg/ml In Methanol

    103. (11.beta.,16.beta.)-9-fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate

    104. 9-fluoro-11.beta.-hydroxy-16.beta.-methyl-3,20-dioxo-17-(propionyloxy)pregna-1,4-dien-21-yl Propionate #

    105. 9alpha-fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-1,4-pregnadiene-3,20-dione 17,21-dipropionate

    106. 9alpha-fluoro-11beta,17alpha,21-trihydroxy-16beta-methyl-3,20-dioxopregna-1,4-diene- 17,21-diyl Dipropionate

    107. Pregna-1,4-diene-3,20-dione, 9-fluoro-11-.beta.,17,21-trihydroxy-16-.beta.-methyl-,17,21-dipropionate

    108. Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11.beta.,16.beta.)

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 504.6 g/mol
    Molecular Formula C28H37FO7
    XLogP33.6
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count8
    Rotatable Bond Count8
    Exact Mass504.25233168 g/mol
    Monoisotopic Mass504.25233168 g/mol
    Topological Polar Surface Area107 Ų
    Heavy Atom Count36
    Formal Charge0
    Complexity1050
    Isotope Atom Count0
    Defined Atom Stereocenter Count8
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 6  
    Drug NameBetamethasone dipropionate
    PubMed HealthBetamethasone Dipropionate (On the skin)
    Drug ClassesCorticosteroid, Strong
    Drug LabelBetamethasone Dipropionate Lotion USP 0.05% (Augmented) contains betamethasone dipropionate, USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a sli...
    Active IngredientBetamethasone dipropionate
    Dosage FormLotion; Ointment, augmented; Ointment; Lotion, augmented; Cream; Cream, augmented; Gel, augmented
    RouteTopical
    Strengtheq 0.05% base
    Market StatusPrescription
    CompanyGlenmark Generics; Fougera Pharms; Actavis Mid Atlantic; Teva; Perrigo New York; Taro; Fougera; Tolmar

    2 of 6  
    Drug NameDiprolene
    PubMed HealthBetamethasone Dipropionate, Augmented (On the skin)
    Drug ClassesCorticosteroid, Very Strong
    Drug LabelDIPROLENE (augmented betamethasone dipropionate) Ointment contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a...
    Active IngredientBetamethasone dipropionate
    Dosage FormOintment, augmented; Lotion, augmented
    RouteTopical
    Strengtheq 0.05% base
    Market StatusPrescription
    CompanyMerck Sharp Dohme

    3 of 6  
    Drug NameDiprolene af
    PubMed HealthBetamethasone Dipropionate, Augmented (On the skin)
    Drug ClassesCorticosteroid, Very Strong
    Drug LabelDIPROLENE AF Cream 0.05% contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use in an emollient base. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degre...
    Active IngredientBetamethasone dipropionate
    Dosage FormCream, augmented
    RouteTopical
    Strengtheq 0.05% base
    Market StatusPrescription
    CompanyMerck Sharp Dohme

    4 of 6  
    Drug NameBetamethasone dipropionate
    PubMed HealthBetamethasone Dipropionate (On the skin)
    Drug ClassesCorticosteroid, Strong
    Drug LabelBetamethasone Dipropionate Lotion USP 0.05% (Augmented) contains betamethasone dipropionate, USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a sli...
    Active IngredientBetamethasone dipropionate
    Dosage FormLotion; Ointment, augmented; Ointment; Lotion, augmented; Cream; Cream, augmented; Gel, augmented
    RouteTopical
    Strengtheq 0.05% base
    Market StatusPrescription
    CompanyGlenmark Generics; Fougera Pharms; Actavis Mid Atlantic; Teva; Perrigo New York; Taro; Fougera; Tolmar

    5 of 6  
    Drug NameDiprolene
    PubMed HealthBetamethasone Dipropionate, Augmented (On the skin)
    Drug ClassesCorticosteroid, Very Strong
    Drug LabelDIPROLENE (augmented betamethasone dipropionate) Ointment contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a...
    Active IngredientBetamethasone dipropionate
    Dosage FormOintment, augmented; Lotion, augmented
    RouteTopical
    Strengtheq 0.05% base
    Market StatusPrescription
    CompanyMerck Sharp Dohme

    6 of 6  
    Drug NameDiprolene af
    PubMed HealthBetamethasone Dipropionate, Augmented (On the skin)
    Drug ClassesCorticosteroid, Very Strong
    Drug LabelDIPROLENE AF Cream 0.05% contains betamethasone dipropionate USP, a synthetic adrenocorticosteroid, for dermatologic use in an emollient base. Betamethasone, an analog of prednisolone, has a high degree of corticosteroid activity and a slight degre...
    Active IngredientBetamethasone dipropionate
    Dosage FormCream, augmented
    RouteTopical
    Strengtheq 0.05% base
    Market StatusPrescription
    CompanyMerck Sharp Dohme

    5 Pharmacology and Biochemistry
    5.1 MeSH Pharmacological Classification

    Anti-Inflammatory Agents

    Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)

    5.2 FDA Pharmacological Classification
    5.2.1 Pharmacological Classes
    Corticosteroid [EPC]; Corticosteroid Hormone Receptor Agonists [MoA]

    API Reference Price

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D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1678905000,"product":"BETAMETHASONE DIPROPIONATE USP","address":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. VAISHNODE","city":"AHMEDABAD","supplier":"AXPLORA","supplierCountry":"ITALY","foreign_port":"NA","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"0.92","actualQuantity":"0.92","unit":"KGS","unitRateFc":"5000","totalValueFC":"4669.9","currency":"USD","unitRateINR":"417500","date":"16-Mar-2023","totalValueINR":"384100","totalValueInUsd":"4669.9","indian_port":"BOMBAY AIR","hs_no":"29372200","bill_no":"5081595","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. 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VAISHNODE","city":"AHMEDABAD","supplier":"AXPLORA","supplierCountry":"ITALY","foreign_port":"NA","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"0.24","actualQuantity":"0.24","unit":"KGS","unitRateFc":"5000","totalValueFC":"1212.5","currency":"USD","unitRateINR":"415249.7","date":"16-Jun-2023","totalValueINR":"99660.12","totalValueInUsd":"1212.5","indian_port":"BOMBAY AIR","hs_no":"29372200","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. VAISHNODE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1686853800,"product":"BETAMETHASONE DIPROPIONATE USP (QTY. 0.68 KGS)","address":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. 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VAISHNODE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1698604200,"product":"BETAMETHASONE DIPROPIONATE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"AXPLORA","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"0.92","actualQuantity":"0.92","unit":"KGS","unitRateFc":"5000","totalValueFC":"4653.6","currency":"USD","unitRateINR":"421000","date":"30-Oct-2023","totalValueINR":"387320","totalValueInUsd":"4653.6","indian_port":"Delhi Air","hs_no":"29372200","bill_no":"8541521","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"N\/A","supplierAddress":"VIA PAVIA 1 27027 GROPELLO CAIROLI ITALY","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701973800,"product":"BETAMETHASONE DIPROPIONATE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"AXPLORA","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"1.84","actualQuantity":"1.84","unit":"KGS","unitRateFc":"5000","totalValueFC":"9316.8","currency":"USD","unitRateINR":"421500","date":"08-Dec-2023","totalValueINR":"775560","totalValueInUsd":"9316.8","indian_port":"Bombay Air","hs_no":"29372200","bill_no":"9129862","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA PAVIA 1- 27027 GROPELLO CAIROLI(PV) CAIROLI, , ItalySDNF Italy","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1705948200,"product":"BETAMETHASONE DIPROPIONATE USP","address":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H","city":"AHMEDABAD,GUJARAT","supplier":"AXPLORA","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"0.92","actualQuantity":"0.92","unit":"KGS","unitRateFc":"5000","totalValueFC":"4654.7","currency":"USD","unitRateINR":"420500","date":"23-Jan-2024","totalValueINR":"386860","totalValueInUsd":"4654.7","indian_port":"Bombay Air","hs_no":"29372200","bill_no":"9795501","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"VIA PAVIA 1- 27027 GROPELLO CAIROLI(PV) CAIROLI, , ItalySDNF Italy","customerAddress":"ZYDUS TOWER, SARKHEJ-GANDHINAGAR,H"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1708540200,"product":"BETAMETHASONE DIPROPIONATE USP2023, PH. 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    02-Jan-2021
    28-Feb-2025
    KGS
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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - OINTMENT, AUGMENTED;TOPICAL - EQ 0.0...DOSAGE - OINTMENT, AUGMENTED;TOPICAL - EQ 0.05% BASE

    USFDA APPLICATION NUMBER - 18741

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    DOSAGE - CREAM;TOPICAL - EQ 0.05% BASE;1% **F...DOSAGE - CREAM;TOPICAL - EQ 0.05% BASE;1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 18827

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    DOSAGE - CREAM;TOPICAL - EQ 0.05% BASE

    USFDA APPLICATION NUMBER - 19137

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    DOSAGE - OINTMENT;TOPICAL - EQ 0.05% BASE

    USFDA APPLICATION NUMBER - 19141

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    DOSAGE - CREAM, AUGMENTED;TOPICAL - EQ 0.05% ...DOSAGE - CREAM, AUGMENTED;TOPICAL - EQ 0.05% BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19555

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    DOSAGE - LOTION, AUGMENTED;TOPICAL - EQ 0.05%...DOSAGE - LOTION, AUGMENTED;TOPICAL - EQ 0.05% BASE **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19716

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    DOSAGE - OINTMENT;TOPICAL - 0.064%;0.005%

    USFDA APPLICATION NUMBER - 21852

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    DOSAGE - SUSPENSION;TOPICAL - 0.064%;0.005%

    USFDA APPLICATION NUMBER - 22185

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    ABOUT THIS PAGE

    Looking for 5593-20-4 / Betamethasone Dipropionate API manufacturers, exporters & distributors?

    Betamethasone Dipropionate manufacturers, exporters & distributors 1

    14

    PharmaCompass offers a list of Betamethasone Dipropionate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Betamethasone Dipropionate manufacturer or Betamethasone Dipropionate supplier for your needs.

    Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Betamethasone Dipropionate manufacturer or Betamethasone Dipropionate supplier.

    PharmaCompass also assists you with knowing the Betamethasone Dipropionate API Price utilized in the formulation of products. Betamethasone Dipropionate API Price is not always fixed or binding as the Betamethasone Dipropionate Price is obtained through a variety of data sources. The Betamethasone Dipropionate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

    API | Excipient name

    Betamethasone Dipropionate

    Synonyms

    Diprolene, Diprosone, 5593-20-4, Maxivate, Diprolene af, Alphatrex

    Cas Number

    5593-20-4

    Unique Ingredient Identifier (UNII)

    826Y60901U

    About Betamethasone Dipropionate

    Betamethasone Dipropionate is the 17,21-dipropionate ester of betamethasone, a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. Betamethasone dipropionate binds to specific intracellular glucocorticoid receptors and subsequently binds to DNA to modify gene expression. The synthesis of certain anti-inflammatory proteins is induced while the synthesis of certain inflammatory mediators is inhibited. As a result, there is an overall reduction in chronic inflammation and autoimmune reactions.

    Maxivate Manufacturers

    A Maxivate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Maxivate, including repackagers and relabelers. The FDA regulates Maxivate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Maxivate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Maxivate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Maxivate Suppliers

    A Maxivate supplier is an individual or a company that provides Maxivate active pharmaceutical ingredient (API) or Maxivate finished formulations upon request. The Maxivate suppliers may include Maxivate API manufacturers, exporters, distributors and traders.

    click here to find a list of Maxivate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Maxivate USDMF

    A Maxivate DMF (Drug Master File) is a document detailing the whole manufacturing process of Maxivate active pharmaceutical ingredient (API) in detail. Different forms of Maxivate DMFs exist exist since differing nations have different regulations, such as Maxivate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Maxivate DMF submitted to regulatory agencies in the US is known as a USDMF. Maxivate USDMF includes data on Maxivate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Maxivate USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Maxivate suppliers with USDMF on PharmaCompass.

    Maxivate JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Maxivate Drug Master File in Japan (Maxivate JDMF) empowers Maxivate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Maxivate JDMF during the approval evaluation for pharmaceutical products. At the time of Maxivate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Maxivate suppliers with JDMF on PharmaCompass.

    Maxivate KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Maxivate Drug Master File in Korea (Maxivate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Maxivate. The MFDS reviews the Maxivate KDMF as part of the drug registration process and uses the information provided in the Maxivate KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Maxivate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Maxivate API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Maxivate suppliers with KDMF on PharmaCompass.

    Maxivate CEP

    A Maxivate CEP of the European Pharmacopoeia monograph is often referred to as a Maxivate Certificate of Suitability (COS). The purpose of a Maxivate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Maxivate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Maxivate to their clients by showing that a Maxivate CEP has been issued for it. The manufacturer submits a Maxivate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Maxivate CEP holder for the record. Additionally, the data presented in the Maxivate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Maxivate DMF.

    A Maxivate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Maxivate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Maxivate suppliers with CEP (COS) on PharmaCompass.

    Maxivate WC

    A Maxivate written confirmation (Maxivate WC) is an official document issued by a regulatory agency to a Maxivate manufacturer, verifying that the manufacturing facility of a Maxivate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Maxivate APIs or Maxivate finished pharmaceutical products to another nation, regulatory agencies frequently require a Maxivate WC (written confirmation) as part of the regulatory process.

    click here to find a list of Maxivate suppliers with Written Confirmation (WC) on PharmaCompass.

    Maxivate NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Maxivate as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Maxivate API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Maxivate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Maxivate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Maxivate NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Maxivate suppliers with NDC on PharmaCompass.

    Maxivate GMP

    Maxivate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Maxivate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Maxivate GMP manufacturer or Maxivate GMP API supplier for your needs.

    Maxivate CoA

    A Maxivate CoA (Certificate of Analysis) is a formal document that attests to Maxivate's compliance with Maxivate specifications and serves as a tool for batch-level quality control.

    Maxivate CoA mostly includes findings from lab analyses of a specific batch. For each Maxivate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Maxivate may be tested according to a variety of international standards, such as European Pharmacopoeia (Maxivate EP), Maxivate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Maxivate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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