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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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$ 0

MARKET PLACE

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API

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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Data Compilation #PharmaFlow

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Chemistry

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Also known as: Mebolazine, Dymethazine, Mebolazine [inn], Roxilon, 69c642i19v, 3625-07-8
Molecular Formula
C42H68N2O2
Molecular Weight
633.0  g/mol
InChI Key
POPWFGNRCCUJGU-RSSVFQIBSA-N
FDA UNII
69C642I19V

Mebolazine
1 2D Structure

Mebolazine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3E,5S,8R,9S,10S,13S,14S,17S)-3-[(E)-[(2R,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-2,10,13,17-tetramethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-3-ylidene]hydrazinylidene]-2,10,13,17-tetramethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-17-ol
2.1.2 InChI
InChI=1S/C42H68N2O2/c1-25-23-37(3)27(9-11-29-31(37)13-17-39(5)33(29)15-19-41(39,7)45)21-35(25)43-44-36-22-28-10-12-30-32(38(28,4)24-26(36)2)14-18-40(6)34(30)16-20-42(40,8)46/h25-34,45-46H,9-24H2,1-8H3/b43-35+,44-36+/t25-,26-,27+,28+,29-,30-,31+,32+,33+,34+,37+,38+,39+,40+,41+,42+/m1/s1
2.1.3 InChI Key
POPWFGNRCCUJGU-RSSVFQIBSA-N
2.1.4 Canonical SMILES
CC1CC2(C(CCC3C2CCC4(C3CCC4(C)O)C)CC1=NN=C5CC6CCC7C8CCC(C8(CCC7C6(CC5C)C)C)(C)O)C
2.1.5 Isomeric SMILES
C[C@H]1/C(=N/N=C\2/[C@@H](C[C@@]3([C@@H]4[C@H]([C@H]5[C@@]([C@](CC5)(O)C)(CC4)C)CC[C@H]3C2)C)C)/C[C@H]6[C@](C1)([C@@H]7[C@H]([C@H]8[C@@]([C@](CC8)(O)C)(CC7)C)CC6)C
2.2 Other Identifiers
2.2.1 UNII
69C642I19V
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one Azine

2. Dimetazin

3. Mebolazine

2.3.2 Depositor-Supplied Synonyms

1. Mebolazine

2. Dymethazine

3. Mebolazine [inn]

4. Roxilon

5. 69c642i19v

6. 3625-07-8

7. Mebolazina

8. Mebolazinum

9. Mebulazina

10. Mebolazina [dcit]

11. Dymethazine(mebalozine)

12. Mebolazinum [inn-latin]

13. Mebulazina [inn-spanish]

14. Chembl2104416

15. Unii-69c642i19v

16. Zinc97978595

17. 17-beta-hydroxy-2-alpha,17-dimethyl-5-alpha-androstan-3-one Azine

18. 17beta-hydroxy-2alpha,17-dimethyl-5alpha-androstan-3-one Azine

19. 2-.alpha.-dimethyl-5-.alpha.-androstan-17-beta-ol-3,3'-azine

20. 17.beta.-hydroxy-2.alpha.,17-dimethyl-5.alpha.-androstan-3-one Azine

21. 17.beta.-hydroxy-2.alpha.,17.beta.-dimethyl-5.alpha.-androstan-3-one-azine

22. 5.alpha.-androstan-3-one, 17.beta.-hydroxy-2.alpha.,17-dimethyl-, Azine

23. 710dieselbolan17b-hydroxy 2a, 17a-dimethyl 5a-androstan-3-one Azine

24. (2r,3e,5s,8r,9s,10s,13s,14s,17s)-3-[(e)-[(2r,5s,8r,9s,10s,13s,14s,17s)-17-hydroxy-2,10,13,17-tetramethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1h-cyclopenta[a]phenanthren-3-ylidene]hydrazinylidene]-2,10,13,17-tetramethyl-2,4,5,6,7,8,9,11,12,14,15,16-dodecahydro-1h-cyclopenta[a]phenanthren-17-ol

2.4 Create Date
2012-11-30
3 Chemical and Physical Properties
Molecular Weight 633.0 g/mol
Molecular Formula C42H68N2O2
XLogP39.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass632.52807942 g/mol
Monoisotopic Mass632.52807942 g/mol
Topological Polar Surface Area65.2 Ų
Heavy Atom Count46
Formal Charge0
Complexity1210
Isotope Atom Count0
Defined Atom Stereocenter Count16
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Mebolazine Manufacturers

A Mebolazine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mebolazine, including repackagers and relabelers. The FDA regulates Mebolazine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mebolazine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Mebolazine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Mebolazine Suppliers

A Mebolazine supplier is an individual or a company that provides Mebolazine active pharmaceutical ingredient (API) or Mebolazine finished formulations upon request. The Mebolazine suppliers may include Mebolazine API manufacturers, exporters, distributors and traders.

click here to find a list of Mebolazine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Mebolazine GMP

Mebolazine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Mebolazine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mebolazine GMP manufacturer or Mebolazine GMP API supplier for your needs.

Mebolazine CoA

A Mebolazine CoA (Certificate of Analysis) is a formal document that attests to Mebolazine's compliance with Mebolazine specifications and serves as a tool for batch-level quality control.

Mebolazine CoA mostly includes findings from lab analyses of a specific batch. For each Mebolazine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Mebolazine may be tested according to a variety of international standards, such as European Pharmacopoeia (Mebolazine EP), Mebolazine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mebolazine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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