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    Chemistry

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    Also known as: 826-39-1, Inversine, Mevasin, Mecamylamine (hydrochloride), Mevasine, Mecamylamine hcl
    Molecular Formula
    C11H22ClN
    Molecular Weight
    203.75  g/mol
    InChI Key
    PKVZBNCYEICAQP-UHFFFAOYSA-N
    FDA UNII
    4956DJR58O
    Mecamylamine Hydrochloride
    1 2D Structure

    Mecamylamine Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine;hydrochloride
    2.1.2 InChI
    InChI=1S/C11H21N.ClH/c1-10(2)8-5-6-9(7-8)11(10,3)12-4;/h8-9,12H,5-7H2,1-4H3;1H
    2.1.3 InChI Key
    PKVZBNCYEICAQP-UHFFFAOYSA-N
    2.1.4 Canonical SMILES
    CC1(C2CCC(C2)C1(C)NC)C.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    4956DJR58O
    2.3 Synonyms
    2.3.1 Depositor-Supplied Synonyms

    1. 826-39-1

    2. Inversine

    3. Mevasin

    4. Mecamylamine (hydrochloride)

    5. Mevasine

    6. Mecamylamine Hcl

    7. N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine Hydrochloride

    8. Mecamylamine, Hcl

    9. N,2,3,3-tetramethyl-2-norbornanamine Hydrochloride

    10. Nsc-757086

    11. Mecamylamine Hydrochloride [usp]

    12. 4956djr58o

    13. Bicyclo(2.2.1)heptan-2-amine, N,2,3,3-tetramethyl-, Hydrochloride

    14. Mekamin Hydrochloride

    15. Mecamine Hydrochloride

    16. Mecamylamine Hydrochloride (usp)

    17. Vecamyl

    18. Sr-01000075329

    19. Einecs 212-555-8

    20. 3-methylaminoisocamphane Hydrochloride

    21. 3-methylaminoisokamfan Chlorid [czech]

    22. Inversin

    23. N-methyl-dl-isobornylamine Hydrochloride

    24. Inversene

    25. N,2,2,3-tetramethylbicyclo[2.2.1]heptan-3-amine;hydrochloride

    26. 3-methylaminoisokamfan Chlorid

    27. Unii-4956djr58o

    28. Cpdb 0059

    29. Inversine (tn)

    30. Mecamylamine Chloride

    31. 2-norbornanamine, N,2,3,3-tetramethyl-, Hydrochloride

    32. N-methyl-n-2,5-endomethylene-1,6,6-trimethylcyclohexylamine Hydrochloride

    33. Atg-3

    34. Schembl123951

    35. Chebi:6707

    36. Chembl1237082

    37. Niosh/rb7466510

    38. Agi-004

    39. Atg-003

    40. Dtxsid70896795

    41. Hms1571o04

    42. Pharmakon1600-01500374

    43. Hy-b1395

    44. Tox21_500841

    45. Ccg-39679

    46. Mfcd00151462

    47. Nsc757086

    48. Akos015963326

    49. Asa 185/13

    50. Lp00841

    51. Mecamylamine Hydrochloride [mi]

    52. Nsc 757086

    53. 2-(methylamino)isocamphane Hydrochloride

    54. Ncgc00094171-01

    55. Ncgc00094171-02

    56. Ncgc00094171-03

    57. Ncgc00261526-01

    58. Ac-19862

    59. Ls-14021

    60. Mecamylamine Hydrochloride [mart.]

    61. Mecamylamine Hydrochloride [vandf]

    62. Mecamylamine Hydrochloride [usp-rs]

    63. Mecamylamine Hydrochloride [who-dd]

    64. 2-[1,2,4]triazol-1-ylmethyl-benzoicacid

    65. Db-056643

    66. Cs-0013122

    67. Eu-0100841

    68. Ft-0603516

    69. Ft-0670962

    70. Ft-0670963

    71. Ft-0670964

    72. Rb74665100

    73. D00611

    74. M 9020

    75. Mecamylamine Hydrochloride [orange Book]

    76. Mecamylamine Hydrochloride [usp Monograph]

    77. N,2,3,3-tetramethyl-2-norcamphanamine Hydrochloride

    78. Q-201341

    79. Sr-01000075329-1

    80. Sr-01000075329-6

    81. Q27259230

    82. 2-(methylamino)-2,3,3-trimethylnorbornane Hydrochloride

    83. Mecamylamine Hydrochloride 100 Microg/ml In Acetonitrile

    84. N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine;hydrochloride

    85. Norbornane, 2-(methylamino)-2,3,3-trimethyl-, Hydrochloride

    86. Bicyclo[2.2.1]heptan-2-amine, N,2,3,3-tetramethyl-, Hydrochloride (1:1)

    2.4 Create Date
    2005-03-27
    3 Chemical and Physical Properties
    Molecular Weight 203.75 g/mol
    Molecular Formula C11H22ClN
    Hydrogen Bond Donor Count2
    Hydrogen Bond Acceptor Count1
    Rotatable Bond Count1
    Exact Mass203.1440774 g/mol
    Monoisotopic Mass203.1440774 g/mol
    Topological Polar Surface Area12 Ų
    Heavy Atom Count13
    Formal Charge0
    Complexity197
    Isotope Atom Count0
    Defined Atom Stereocenter Count0
    Undefined Atom Stereocenter Count3
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 2  
    Drug NameMecamylamine hydrochloride
    Active IngredientMecamylamine hydrochloride
    Dosage FormTablet
    RouteOral
    Strength2.5mg
    Market StatusPrescription
    CompanyNexgen Pharma

    2 of 2  
    Drug NameMecamylamine hydrochloride
    Active IngredientMecamylamine hydrochloride
    Dosage FormTablet
    RouteOral
    Strength2.5mg
    Market StatusPrescription
    CompanyNexgen Pharma

    5 Pharmacology and Biochemistry
    5.1 FDA Pharmacological Classification
    5.1.1 Pharmacological Classes
    Decreased Autonomic Ganglionic Activity [PE]; Autonomic Ganglionic Blocker [EPC]

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