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Meclofenoxate Hydrochloride
Also known as: 3685-84-5, Meclofenoxate hcl, Centrophenoxine hydrochloride, Lucidril, Cerutil, Marucotol
Molecular Formula
C12H17Cl2NO3
Molecular Weight
294.17  g/mol
InChI Key
FIVHOHCAXWQPGC-UHFFFAOYSA-N
FDA UNII
5BK3070BDY

An ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid.
1 2D Structure

Meclofenoxate Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate;hydrochloride
2.1.2 InChI
InChI=1S/C12H16ClNO3.ClH/c1-14(2)7-8-16-12(15)9-17-11-5-3-10(13)4-6-11;/h3-6H,7-9H2,1-2H3;1H
2.1.3 InChI Key
FIVHOHCAXWQPGC-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CN(C)CCOC(=O)COC1=CC=C(C=C1)Cl.Cl
2.2 Other Identifiers
2.2.1 UNII
5BK3070BDY
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Atsefen

2. Centrophenoxine

3. Cerutil

4. Cetrexin

5. Helfergin

6. Meclofenoxate

2.3.2 Depositor-Supplied Synonyms

1. 3685-84-5

2. Meclofenoxate Hcl

3. Centrophenoxine Hydrochloride

4. Lucidril

5. Cerutil

6. Marucotol

7. Brenal

8. Atsefen

9. Cellative

10. Proserout

11. Acefen

12. Helfergin

13. Centrofenoxin

14. Amipolen

15. Methoxynal

16. Meclophenoxate Hydrochloride

17. Meclofenoxate (hydrochloride)

18. 235 Anp Hydrochloride

19. 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate Hydrochloride

20. Dimethylaminoethyl P-chlorophenoxyacetate Hydrochloride

21. 2-(dimethylamino)ethyl (4-chlorophenoxy)acetate Hydrochloride

22. Lucidryl Hydrochloride

23. Meclofenoxate Hydrochloride [jan]

24. Meclofenoxate (centrophenoxine) Hcl

25. Dimethylaminoethyl 4-chlorophenoxyacetate Hydrochloride

26. 5bk3070bdy

27. Nsc-4268

28. Nsc-113619

29. 2-(dimethylamino)ethyl (p-chlorophenoxy)acetate Hydrochloride

30. Lutiaron

31. Dsstox_cid_25141

32. Dsstox_rid_80699

33. Dsstox_gsid_45141

34. Centrophenoxine (van)

35. 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate;hydrochloride

36. Wln: Gr Do1vo2n1&1 &gh

37. Acetic Acid, 2-(4-chlorophenoxy)-, 2-(dimethylamino)ethyl Ester, Hydrochloride (1:1)

38. Sr-01000075788

39. Ncgc00015279-02

40. Nsc 4268

41. Einecs 222-975-3

42. Cas-3685-84-5

43. Chlorowodorki Centrofenoksyna [polish]

44. Acetic Acid, 2-(dimethylamino)ethyl Ester Hydrochloride

45. Nsc 113619

46. Chlorowodorki Centrofenoksyna

47. Unii-5bk3070bdy

48. (dimethylamino)ethyl Ester Of (p-chlorophenoxy)acetic Acid Hydrochloride

49. Centrophenoxine Hcl

50. Lucidril (tn)

51. Prestwick_978

52. Acetic Acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl Ester, Hydrochloride

53. P-chlorphenoxyessigsaeure-beta-dimethylaminoaethylesters [german]

54. Dimethylaminoethyl Ester Of P-chlorophenoxyacetic Acid Hydrochloride

55. (p-chlorophenoxy)acetic Acid 2-(dimethylamino)ethyl Ester Hydrochloride

56. Acephen Hydrochloride

57. Mls002153989

58. Schembl218322

59. Spectrum1503226

60. P-chlorphenoxyessigsaeure-beta-dimethylaminoaethylesters

61. Chembl1256131

62. Dtxsid8045141

63. Meclofenoxane Hydrochloride

64. Nsc4268

65. Hms1570i08

66. Hms1922k09

67. Pharmakon1600-01503226

68. Centrophenoxine Hydrochloride, 99%

69. Bcp21567

70. Meclofenoxate Hydrochloride (jp17)

71. Tox21_110123

72. Tox21_302398

73. Tox21_500250

74. Ccg-39961

75. Mfcd00012533

76. Nsc113619

77. Nsc758420

78. S4280

79. 2-(4-chlorophenoxy)acetic Acid 2-(dimethylamino)ethyl Ester Hydrochloride

80. Akos008968424

81. Tox21_110123_1

82. Ac-1680

83. Ks-1179

84. Lp00250

85. Nsc-758420

86. Acetic Acid, (p-chlorophenoxy)-, 2-dimethylaminoethyl Ester, Hydrochloride

87. Meclofenoxate Hydrochloride [mi]

88. Ncgc00015279-08

89. Ncgc00093712-01

90. Ncgc00093712-02

91. Ncgc00093712-03

92. Ncgc00093712-04

93. Ncgc00180932-01

94. Ncgc00256151-01

95. Ncgc00260935-01

96. Hy-17555

97. Smr001233323

98. Meclofenoxate Hydrochloride [mart.]

99. Db-049021

100. Meclofenoxate Hydrochloride [who-dd]

101. Eu-0100250

102. Ft-0603646

103. M2460

104. Sw197063-3

105. En300-35717

106. A14265

107. C 8773

108. D02243

109. H10771

110. Sr-01000075788-1

111. Sr-01000075788-5

112. Sr-01000075788-6

113. W-106584

114. Q27261792

115. Z57281900

116. 2-(dimethylamino)ethyl(p-chlorphenoxy)acetate Hydrochloride

117. Meclofenoxate Hydrochloride 1.0 Mg/ml In Acetonitrile (as Free Base)

118. (4-chlorophenoxy)acetic Acid 2-(dimethylamino)ethyl Ester Hydrochloride

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 294.17 g/mol
Molecular Formula C12H17Cl2NO3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count7
Exact Mass293.0585488 g/mol
Monoisotopic Mass293.0585488 g/mol
Topological Polar Surface Area38.8 Ų
Heavy Atom Count18
Formal Charge0
Complexity228
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Neuroprotective Agents

Drugs intended to prevent damage to the brain or spinal cord from ischemia, stroke, convulsions, or trauma. Some must be administered before the event, but others may be effective for some time after. They act by a variety of mechanisms, but often directly or indirectly minimize the damage produced by endogenous excitatory amino acids. (See all compounds classified as Neuroprotective Agents.)


Nootropic Agents

Drugs used to specifically facilitate learning or memory, particularly to prevent the cognitive deficits associated with dementias. These drugs act by a variety of mechanisms. (See all compounds classified as Nootropic Agents.)


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