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Chemistry

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Also known as: 86347-14-0, 4-(1-(2,3-dimethylphenyl)ethyl)-1h-imidazole, Medetomidina, Medetomidinum, Medetomidinum [latin], Medetomidina [spanish]
Molecular Formula
C13H16N2
Molecular Weight
200.28  g/mol
InChI Key
CUHVIMMYOGQXCV-UHFFFAOYSA-N
FDA UNII
MR15E85MQM

Medetomidine
An agonist of RECEPTORS, ADRENERGIC ALPHA-2 that is used in veterinary medicine for its analgesic and sedative properties. It is the racemate of DEXMEDETOMIDINE.
1 2D Structure

Medetomidine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
2.1.2 InChI
InChI=1S/C13H16N2/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13/h4-8,11H,1-3H3,(H,14,15)
2.1.3 InChI Key
CUHVIMMYOGQXCV-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
2.2 Other Identifiers
2.2.1 UNII
MR15E85MQM
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hydrochloride, Medetomidine

2. Levomedetomidine

3. Medetomidine Hydrochloride

4. Mpv 785

5. Mpv-785

6. Mpv785

2.3.2 Depositor-Supplied Synonyms

1. 86347-14-0

2. 4-(1-(2,3-dimethylphenyl)ethyl)-1h-imidazole

3. Medetomidina

4. Medetomidinum

5. Medetomidinum [latin]

6. Medetomidina [spanish]

7. 4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole

8. 5-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole

9. (+-)-4-(alpha,2,3-trimethylbenzyl)imidazole

10. 1h-imidazole, 4-[1-(2,3-dimethylphenyl)ethyl]-

11. Mr15e85mqm

12. Chembl77921

13. Chebi:48552

14. Medetomidine (inn)

15. Medetomidine [inn]

16. Dexmedetomidina

17. 1h-imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-

18. Medetomidine [inn:ban]

19. (+)-(s)-4-[1-(2,3-dimethylphenyl) Ethyl]-1h -imidazole Monohydrochloride

20. Unii-mr15e85mqm

21. Domtor

22. Mfcd00880557

23. (rs)-4-(alpha,2,3-trimethylbenzyl)imidazol

24. Medetomidine [mi]

25. Domitor [veterinary] (tn)

26. Schembl26432

27. Dtxsid6048258

28. Medetomidine [green Book]

29. Hms3651h20

30. (s)-medetomidine; Dexmedetomidinum

31. Bcp06913

32. Bcp12592

33. Bdbm50036913

34. Mfcd00864346

35. Mfcd24392996

36. Akos016010776

37. Akos037643760

38. Cs-0734

39. Db11428

40. Sb17478

41. As-35172

42. Hy-17034

43. Sy114102

44. Sy116126

45. Db-060542

46. Ft-0666307

47. Ft-0670775

48. Ft-0716677

49. D08165

50. (+/-)-4-(alpha,2,3-trimethylbenzyl)imidazole

51. Ab01566810_01

52. A863235

53. L000223

54. L001361

55. Q427179

56. (+)-4-[1-(2,3-dimethylphenyl)ethyl]-1h-imidazole

57. (rs)-4-[1-(2,3-dimethylphenyl)ethyl]-3h-imidazole

58. Brd-a66563878-003-01-8

59. (+/-)-4-(.alpha.,2,3-trimethylbenzyl)imidazole

60. 1h-imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-, (+/-)-

61. 6918-06-5

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 200.28 g/mol
Molecular Formula C13H16N2
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass200.131348519 g/mol
Monoisotopic Mass200.131348519 g/mol
Topological Polar Surface Area28.7 Ų
Heavy Atom Count15
Formal Charge0
Complexity205
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Analgesics, Non-Narcotic

A subclass of analgesic agents that typically do not bind to OPIOID RECEPTORS and are not addictive. Many non-narcotic analgesics are offered as NONPRESCRIPTION DRUGS. (See all compounds classified as Analgesics, Non-Narcotic.)


Adrenergic alpha-2 Receptor Agonists

Compounds that bind to and activate ADRENERGIC ALPHA-2 RECEPTORS. (See all compounds classified as Adrenergic alpha-2 Receptor Agonists.)


Hypnotics and Sedatives

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)


NDC API

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01

Pharmatory Oy

Finland
Biotech Showcase
Not Confirmed
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Pharmatory Oy

Finland
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Biotech Showcase
Not Confirmed

MEDETOMIDINE

NDC Package Code : 71362-002

Start Marketing Date : 2019-09-27

End Marketing Date : 2024-12-31

Dosage Form (Strength) : POWDER (1kg/kg)

Marketing Category : BULK INGREDIENT

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API Reference Price

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ANTOINE LAVOISIER, No.22 PARQUE CUAUTITLAN IZCALLI, ESTADO DE MEXIC SDNF Mexico","customerAddress":"PLOT NO-51,MEENAKSHI BAMBOO,GACHIB"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731436200,"product":"DEXMEDETOMIDINE HYDROCHLORIDE B.NO:-17004324 (ITEM NO: RMI3000487)","address":"CLARIS CORPORATE HEAD QUARTERS,","city":"ELLISBRIDGE,AHMEDABD,GUJARAT,INDIA","supplier":"RECIPHARM AB","supplierCountry":"ITALY","foreign_port":"MILAN","customer":"BAXTER HEALTHCARE CORPORATION","customerCountry":"INDIA","quantity":"0.13","actualQuantity":"125","unit":"GMS","unitRateFc":"2550","totalValueFC":"321816.4","currency":"USD","unitRateINR":"217260","date":"13-Nov-2024","totalValueINR":"27157500","totalValueInUsd":"321816.4","indian_port":"Ahmedabad Air","hs_no":"29332990","bill_no":"6643789","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN","supplierAddress":"STRADA STATALE DEI GIOVI ,131 2003 7,PAD ERNO DUGNANO (MI) ITALY ITALY ., , ITALY ITALY","customerAddress":"CLARIS CORPORATE HEAD QUARTERS,"}]
08-Feb-2021
13-Nov-2024
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Average Price (USD/KGS)

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Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

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ABOUT THIS PAGE

Medetomidine Manufacturers

A Medetomidine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Medetomidine, including repackagers and relabelers. The FDA regulates Medetomidine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Medetomidine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Medetomidine Suppliers

A Medetomidine supplier is an individual or a company that provides Medetomidine active pharmaceutical ingredient (API) or Medetomidine finished formulations upon request. The Medetomidine suppliers may include Medetomidine API manufacturers, exporters, distributors and traders.

Medetomidine NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Medetomidine as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Medetomidine API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Medetomidine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Medetomidine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Medetomidine NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Medetomidine suppliers with NDC on PharmaCompass.

Medetomidine GMP

Medetomidine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Medetomidine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Medetomidine GMP manufacturer or Medetomidine GMP API supplier for your needs.

Medetomidine CoA

A Medetomidine CoA (Certificate of Analysis) is a formal document that attests to Medetomidine's compliance with Medetomidine specifications and serves as a tool for batch-level quality control.

Medetomidine CoA mostly includes findings from lab analyses of a specific batch. For each Medetomidine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Medetomidine may be tested according to a variety of international standards, such as European Pharmacopoeia (Medetomidine EP), Medetomidine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Medetomidine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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