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Chemistry

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Also known as: Meglumine antimonate, Meglumine antimoniate, N-methylglucamine antimonate, 133-51-7, Methylglucamine antimonate, Protostib
Molecular Formula
C7H18NO8Sb
Molecular Weight
365.98  g/mol
InChI Key
XOGYVDXPYVPAAQ-SESJOKTNSA-M
FDA UNII
75G4TW236W

Meglumine Antimonate
ANTIMONY salt of meglumine that is used in the treatment of LEISHMANIASIS.
1 2D Structure

Meglumine Antimonate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
hydroxy(dioxo)-5-stibane;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
2.1.2 InChI
InChI=1S/C7H17NO5.H2O.2O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;1H2;;;/q;;;;+1/p-1/t4-,5+,6+,7+;;;;/m0..../s1
2.1.3 InChI Key
XOGYVDXPYVPAAQ-SESJOKTNSA-M
2.1.4 Canonical SMILES
CNCC(C(C(C(CO)O)O)O)O.O[Sb](=O)=O
2.1.5 Isomeric SMILES
CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.O[Sb](=O)=O
2.2 Other Identifiers
2.2.1 UNII
75G4TW236W
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Meglumine Antimoniate

2. N Methylglucamine Antimonate

3. N-methylglucamine Antimonate

2.3.2 Depositor-Supplied Synonyms

1. Meglumine Antimonate

2. Meglumine Antimoniate

3. N-methylglucamine Antimonate

4. 133-51-7

5. Methylglucamine Antimonate

6. Protostib

7. 75g4tw236w

8. N-methyl Glucamine Antimoniate

9. 2168-rp

10. Einecs 205-108-3

11. Glucantim

12. Unii-75g4tw236w

13. 1-deoxy-1-(methylamino)glucitol Antimonate(v)

14. 1-deoxy-1-(methylamino)-d-glucitol, Compound With Antimonic Acid (1:1)

15. D-glucitol, 1-deoxy-1-(methylamino)-, Compd. With Antimonic Acid (1:1)

16. Glucitol, 1-deoxy-1-(methylamino)-, Compd. With Antimonic Acid (1:1), D-

17. Schembl146372

18. Dtxsid4043935

19. D-glucitol, 1-deoxy-1-(methylamino)-, Trioxoantimonate(1-)

20. Mfcd01725422

21. Meglumine Antimonate [who-dd]

22. Akos025310684

23. Db13732

24. N-methylglucamine Antimonate [mi]

25. 133m517

26. Q2757969

27. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol Stibenate

28. D-glucitol, 1-deoxy-1-(methylamino)-, Compd. With Antimonic Acid (hsbo3) (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 365.98 g/mol
Molecular Formula C7H18NO8Sb
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass365.00705 g/mol
Monoisotopic Mass365.00705 g/mol
Topological Polar Surface Area168 Ų
Heavy Atom Count17
Formal Charge0
Complexity180
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiprotozoal Agents

Substances that are destructive to protozoans. (See all compounds classified as Antiprotozoal Agents.)


4.2 ATC Code

P - Antiparasitic products, insecticides and repellents

P01 - Antiprotozoals

P01C - Agents against leishmaniasis and trypanosomiasis

P01CB - Antimony compounds

P01CB01 - Meglumine antimonate


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ABOUT THIS PAGE

Meglumine Antimonate Manufacturers

A Meglumine Antimonate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Meglumine Antimonate, including repackagers and relabelers. The FDA regulates Meglumine Antimonate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Meglumine Antimonate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Meglumine Antimonate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Meglumine Antimonate Suppliers

A Meglumine Antimonate supplier is an individual or a company that provides Meglumine Antimonate active pharmaceutical ingredient (API) or Meglumine Antimonate finished formulations upon request. The Meglumine Antimonate suppliers may include Meglumine Antimonate API manufacturers, exporters, distributors and traders.

click here to find a list of Meglumine Antimonate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Meglumine Antimonate USDMF

A Meglumine Antimonate DMF (Drug Master File) is a document detailing the whole manufacturing process of Meglumine Antimonate active pharmaceutical ingredient (API) in detail. Different forms of Meglumine Antimonate DMFs exist exist since differing nations have different regulations, such as Meglumine Antimonate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Meglumine Antimonate DMF submitted to regulatory agencies in the US is known as a USDMF. Meglumine Antimonate USDMF includes data on Meglumine Antimonate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Meglumine Antimonate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Meglumine Antimonate suppliers with USDMF on PharmaCompass.

Meglumine Antimonate GMP

Meglumine Antimonate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Meglumine Antimonate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Meglumine Antimonate GMP manufacturer or Meglumine Antimonate GMP API supplier for your needs.

Meglumine Antimonate CoA

A Meglumine Antimonate CoA (Certificate of Analysis) is a formal document that attests to Meglumine Antimonate's compliance with Meglumine Antimonate specifications and serves as a tool for batch-level quality control.

Meglumine Antimonate CoA mostly includes findings from lab analyses of a specific batch. For each Meglumine Antimonate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Meglumine Antimonate may be tested according to a variety of international standards, such as European Pharmacopoeia (Meglumine Antimonate EP), Meglumine Antimonate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Meglumine Antimonate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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