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Chemistry

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Also known as: Meglumine antimonate, Meglumine antimoniate, N-methylglucamine antimonate, 133-51-7, Methylglucamine antimonate, Protostib
Molecular Formula
C7H18NO8Sb
Molecular Weight
365.98  g/mol
InChI Key
XOGYVDXPYVPAAQ-SESJOKTNSA-M
FDA UNII
75G4TW236W

Meglumine Antimonate
ANTIMONY salt of meglumine that is used in the treatment of LEISHMANIASIS.
1 2D Structure

Meglumine Antimonate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
hydroxy(dioxo)-5-stibane;(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
2.1.2 InChI
InChI=1S/C7H17NO5.H2O.2O.Sb/c1-8-2-4(10)6(12)7(13)5(11)3-9;;;;/h4-13H,2-3H2,1H3;1H2;;;/q;;;;+1/p-1/t4-,5+,6+,7+;;;;/m0..../s1
2.1.3 InChI Key
XOGYVDXPYVPAAQ-SESJOKTNSA-M
2.1.4 Canonical SMILES
CNCC(C(C(C(CO)O)O)O)O.O[Sb](=O)=O
2.1.5 Isomeric SMILES
CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.O[Sb](=O)=O
2.2 Other Identifiers
2.2.1 UNII
75G4TW236W
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Meglumine Antimoniate

2. N Methylglucamine Antimonate

3. N-methylglucamine Antimonate

2.3.2 Depositor-Supplied Synonyms

1. Meglumine Antimonate

2. Meglumine Antimoniate

3. N-methylglucamine Antimonate

4. 133-51-7

5. Methylglucamine Antimonate

6. Protostib

7. 75g4tw236w

8. N-methyl Glucamine Antimoniate

9. 2168-rp

10. Einecs 205-108-3

11. Glucantim

12. Unii-75g4tw236w

13. 1-deoxy-1-(methylamino)glucitol Antimonate(v)

14. 1-deoxy-1-(methylamino)-d-glucitol, Compound With Antimonic Acid (1:1)

15. D-glucitol, 1-deoxy-1-(methylamino)-, Compd. With Antimonic Acid (1:1)

16. Glucitol, 1-deoxy-1-(methylamino)-, Compd. With Antimonic Acid (1:1), D-

17. Schembl146372

18. Dtxsid4043935

19. D-glucitol, 1-deoxy-1-(methylamino)-, Trioxoantimonate(1-)

20. Mfcd01725422

21. Meglumine Antimonate [who-dd]

22. Akos025310684

23. Db13732

24. N-methylglucamine Antimonate [mi]

25. 133m517

26. Q2757969

27. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol Stibenate

28. D-glucitol, 1-deoxy-1-(methylamino)-, Compd. With Antimonic Acid (hsbo3) (1:1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 365.98 g/mol
Molecular Formula C7H18NO8Sb
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count9
Rotatable Bond Count6
Exact Mass365.00705 g/mol
Monoisotopic Mass365.00705 g/mol
Topological Polar Surface Area168 Ų
Heavy Atom Count17
Formal Charge0
Complexity180
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiprotozoal Agents

Substances that are destructive to protozoans. (See all compounds classified as Antiprotozoal Agents.)


4.2 ATC Code

P - Antiparasitic products, insecticides and repellents

P01 - Antiprotozoals

P01C - Agents against leishmaniasis and trypanosomiasis

P01CB - Antimony compounds

P01CB01 - Meglumine antimonate


USDMF

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SupplySide West 2024
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Virtual BoothSanofi is a pioneer in Diabetes Solutions, Human Vaccines, Innovative Drugs, Consumer Healthcare, and the new Genzyme.

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DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 36014

Submission : 2021-10-27

Status : Active

Type : II

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Listed Suppliers

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Virtual BoothJai Radhe Sales is your partner for all your sourcing needs.

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Meglumine Antimonate

About the Company : Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete ...

Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete sourcing solutions for pharmaceutical products from India, including technical and regulatory assistance. It believes in providing its customers with high-quality products at reasonable prices. It has always endeavored to achieve global standards in the field of pharmaceuticals and has carved out a niche for itself through new methods based on current market needs. Today, it has established itself as a truly global company, with exports to almost every continent.
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EUROAPI

France
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  • WHO-GMP

Virtual BoothEUROAPI, the leading small molecules API player, provides both API sales & CDMO services.

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Meglumine Antimonate

About the Company : EUROAPI is the market leader in small molecule APIs with projected sales of about €1 billion in 2022. With around 200 APIs, it has one of the largest portfolios in the market. Th...

EUROAPI is the market leader in small molecule APIs with projected sales of about €1 billion in 2022. With around 200 APIs, it has one of the largest portfolios in the market. Thanks to its excellent R&D skills and six manufacturing facilities across Europe, EUROAPI guarantees API manufacturing of the highest quality to its clients in over 80 countries. Its strong innovation and R&D skills helps it to speed the development of more complex molecule segments through CDMO operations. It also offers experience in supply, regulation and quality. EUROAPI employs 3,350 people and is listed on Euronext.
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SupplySide West 2024
Not Confirmed
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SupplySide West 2024
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Meglumine Antimonate

About the Company : The IQT is a Brazilian chemical industry, with 100% national capital, and that is a competitive position among the largest companies in the research and development of various mate...

The IQT is a Brazilian chemical industry, with 100% national capital, and that is a competitive position among the largest companies in the research and development of various materials of industrial application. Throughout our history, we have been responsible for developing the country and pharmochemical new chemical solutions that add value and quality of life for its consumers.
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Maiden Group

India
SupplySide West 2024
Not Confirmed
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Maiden Group

India
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SupplySide West 2024
Not Confirmed

Meglumine Antimonate

About the Company : We are Maiden, a rapidly growing Indian pharma company committed to developing, manufacturing and marketing diverse portfolio of products. Our core strength lies in development, up...

We are Maiden, a rapidly growing Indian pharma company committed to developing, manufacturing and marketing diverse portfolio of products. Our core strength lies in development, up scaling and manufacturing differentiated formulations. Various national and multi-national pharmaceutical companies across geographies rely on our expertises to deliver world class quality products. Maiden complies with various National / International regulatory norms and standards. We strive hard to make a difference in people lives, through our innovative healthcare solutions.
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