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Chemistry

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Also known as: N-methyl-d-glucamine, 6284-40-8, N-methylglucamine, Meglumin, 1-deoxy-1-(methylamino)-d-glucitol, Methylglucamin
Molecular Formula
C7H17NO5
Molecular Weight
195.21  g/mol
InChI Key
MBBZMMPHUWSWHV-BDVNFPICSA-N
FDA UNII
6HG8UB2MUY

Meglumine
1-Deoxy-1-(methylamino)-D-glucitol. A derivative of sorbitol in which the hydroxyl group in position 1 is replaced by a methylamino group. Often used in conjunction with iodinated organic compounds as contrast medium.
1 2D Structure

Meglumine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
2.1.2 InChI
InChI=1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
2.1.3 InChI Key
MBBZMMPHUWSWHV-BDVNFPICSA-N
2.1.4 Canonical SMILES
CNCC(C(C(C(CO)O)O)O)O
2.1.5 Isomeric SMILES
CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
6HG8UB2MUY
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Methylglucamine

2.3.2 Depositor-Supplied Synonyms

1. N-methyl-d-glucamine

2. 6284-40-8

3. N-methylglucamine

4. Meglumin

5. 1-deoxy-1-(methylamino)-d-glucitol

6. Methylglucamin

7. N-methylsorbitylamine

8. D-glucitol, 1-deoxy-1-(methylamino)-

9. Methylglucamine

10. Meglumina

11. Megluminum

12. 1-deoxy-1-methylaminosorbitol

13. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentol

14. (2r,3r,4r,5s)-6-(methylamino)hexane-1,2,3,4,5-pentaol

15. N-methyl-d(-)-glucamine

16. Megluminum [inn-latin]

17. Meglumina [inn-spanish]

18. Sorbitol, 1-deoxy-1-methylamino-

19. Unii-6hg8ub2muy

20. D(-)-n-methylglucamine

21. 6hg8ub2muy

22. Chebi:59732

23. Nsc-7391

24. Nsc-52907

25. Nsc 7391

26. Nsc 52907

27. Dsstox_cid_3244

28. Dsstox_rid_76939

29. Dsstox_gsid_23244

30. Glucitol, 1-deoxy-1-(methylamino)-, D-

31. Einecs 228-506-9

32. N-methylglucamine Solution

33. Nsc52907

34. Meglumine [usp:inn:ban:jan]

35. N-methyl-glucamine

36. N-methyl Glucamine

37. Ncgc00166125-01

38. Cas-6284-40-8

39. Mfcd00004707

40. Meglumine [inn]

41. Meglumine [jan]

42. Meglumine [ii]

43. N-methylglucamine Solution (70% Or Less)

44. Meglumine [vandf]

45. Meglumine [mart.]

46. Ec 228-506-9

47. Meglumine [usp-rs]

48. Meglumine [who-dd]

49. Meglumine [who-ip]

50. Schembl2193

51. Bidd:gt0676

52. Methylglucamine [inci]

53. Meglumine (jp17/usp/inn)

54. N-methylglucamine [mi]

55. Meglumine [orange Book]

56. Chembl1200570

57. Dtxsid0023244

58. Meglumine [ep Monograph]

59. Meglumine [usp Monograph]

60. Megluminum [who-ip Latin]

61. 1-deoxy-1-(methylamino)-glucitol

62. 1-methylamino-1-deoxy-d-glucitol

63. Hms2089b05

64. Hms3714b10

65. Pharmakon1600-01300029

66. Hy-b0342

67. Zinc2020259

68. Tox21_112330

69. Tox21_302037

70. Nsc759607

71. S1974

72. Akos005167162

73. Akos015850890

74. N-methyl-1-amino-1-deoxy-d-glucitol

75. Tox21_112330_1

76. Ac-4692

77. Ccg-220884

78. Nsc-759607

79. Meglumine 100 Microg/ml In Acetonitrile

80. Ncgc00166125-02

81. Ncgc00255365-01

82. Ac-17087

83. As-12002

84. Sbi-0206683.p002

85. Meglumine, Meets Usp Testing Specifications

86. Am20100540

87. M0227

88. Sw199350-2

89. D01796

90. Ab00430469-03

91. Ab00430469_05

92. A834035

93. Q288875

94. Sr-05000001446

95. N-methyl-d-glucamine, 99.0-100.5% (titration)

96. Sr-05000001446-1

97. Brd-k28595280-001-01-1

98. N-methyl-d-glucamine, Vetec(tm) Reagent Grade, 99%

99. Wurcs=2.0/1,1,0/[h2122h_1*nc]/1/

100. N-methyl-d-glucamine, Reagentplus(r), >=99.0% (t)

101. (2r,3r,4r,5s)-6-methylamino-hexane-1,2,3,4,5-pentaol

102. Meglumine, United States Pharmacopeia (usp) Reference Standard

103. N-methyl-(2 (s),3 (r),4 (r),5 (r),6-pentahydroxy-hexyl)-amine

104. Meglumine, Pharmaceutical Secondary Standard; Certified Reference Material

105. N-methyl-d-glucamine, European Pharmacopoeia (ep) Reference Standard

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 195.21 g/mol
Molecular Formula C7H17NO5
XLogP3-2.8
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass195.11067264 g/mol
Monoisotopic Mass195.11067264 g/mol
Topological Polar Surface Area113 Ų
Heavy Atom Count13
Formal Charge0
Complexity134
Isotope Atom Count0
Defined Atom Stereocenter Count4
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Contrast Media

Substances used to allow enhanced visualization of tissues. (See all compounds classified as Contrast Media.)


USDMF

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Schering Ag

Germany

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Schering Ag

Germany
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GDUFA

DMF Review : N/A

Rev. Date :

Pay. Date :

DMF Number : 4308

Submission : 1981-08-28

Status : Inactive

Type : II

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Eagle Chemical Works

India

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Merck Kgaa

Germany

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Merck Kgaa

Germany
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GDUFA

DMF Review : Complete

Rev. Date : 2016-11-10

Pay. Date : 2016-09-30

DMF Number : 3413

Submission : 1978-10-17

Status : Active

Type : II

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Meglumine

Registrant Name : Leaders Bio Co., Ltd.

Registration Date : 2018-07-21

Registration Number : 20180721-210-J-246

Manufacturer Name : Zenji Pharmaceuticals (Suzho...

Manufacturer Address : No.122, Xuqing Road, Xuguan Town, Suzhou, Jiangsu, China

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Midas Pharma

Germany
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Virtual BoothMidas Pharma provides expertise in developing and supplying APIs, finished products, and intermediates.

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Meglumine

About the Company : Midas Pharma is a pharmaceutical company that excels in providing extensive expertise while fostering connections between companies, individuals, and knowledge. The core competence...

Midas Pharma is a pharmaceutical company that excels in providing extensive expertise while fostering connections between companies, individuals, and knowledge. The core competence of Midas Pharma lies in project management related to pharmaceutical supply chains. The company is actively involved in sourcing, supplying, and developing Active Pharmaceutical Ingredients (API) and Finished Dosage Forms (FDF) manufactured by its contract manufacturing partners. For each project or product, Midas Pharma selects the most suitable match from its network of manufacturing partners.
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Virtual BoothJai Radhe Sales is your partner for all your sourcing needs.

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Meglumine

About the Company : Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete ...

Jai Radhe Sales was founded in 1999 as an out-of-the-box distribution firm specializing in the global supply of high-quality pharmaceutical ingredients. The firm provides complete sourcing solutions for pharmaceutical products from India, including technical and regulatory assistance. It believes in providing its customers with high-quality products at reasonable prices. It has always endeavored to achieve global standards in the field of pharmaceuticals and has carved out a niche for itself through new methods based on current market needs. Today, it has established itself as a truly global company, with exports to almost every continent.
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Virtual BoothChynops Pharma is an ideal sourcing partner for high-quality APIs, advanced intermediates, speciality chemicals & excipients.

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Meglumine

About the Company : Chynops Pharma, a company certified with ISO 9001:2015, is situated in Ahmedabad, India. We specialize in exporting, supplying, and trading a wide range of products, including APIs...

Chynops Pharma, a company certified with ISO 9001:2015, is situated in Ahmedabad, India. We specialize in exporting, supplying, and trading a wide range of products, including APIs, Advanced Drug Intermediates, Impurity Standards, Working Standards, KSMs, Industrial Chemicals, Specialty Chemicals, Excipients, Amino Acids, Vitamins, Minerals, Herbal Extracts, Essential Oils, Prebiotics & Probiotics, Veterinary APIs, Solvents, and more from India. Our commitment extends to providing these products to valued customers in both the domestic and global markets.
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Meglumine

About the Company : Delmar Biopharma's range of excipients covers the entire spectrum of pharmaceutical applications, featuring over 100 high-quality products. Manufactured in our state-of-the-art GMP...

Delmar Biopharma's range of excipients covers the entire spectrum of pharmaceutical applications, featuring over 100 high-quality products. Manufactured in our state-of-the-art GMP-approved facility, we offer essential excipients such as binders, fillers, and disintegrants. In addition, we supply a variety of Active Pharmaceutical Ingredients (APIs) and pharmaceutical intermediates. We assure our customers that we can fulfill all their requirements, providing a solution for every need.
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Grupo Juste

Spain
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Spain
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Meglumine

About the Company : The Juste Group is the result of a merger of two companies: Justesa Imagen, centered on Chemicals, and Juste Farma, a pharmaceutical company. It has completed 100 years of growth, ...

The Juste Group is the result of a merger of two companies: Justesa Imagen, centered on Chemicals, and Juste Farma, a pharmaceutical company. It has completed 100 years of growth, continuously improving our capacity for developing, producing, and distributing active pharmaceutical ingredients and medicines. We research, develop, produce, and distribute pharmaceuticals and active ingredients for the pharmaceutical industry in Europe, the U.S.A. and Canada, Central and South America, the Middle East, and India.
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Meglumine

About the Company : Guangzhou Tosun Pharmaceutical was founded in 1999, which mainly focuses on importation & exportation of Active Pharmaceutical Ingrediants, Chemical Raw Materials, Intermediate, Ex...

Guangzhou Tosun Pharmaceutical was founded in 1999, which mainly focuses on importation & exportation of Active Pharmaceutical Ingrediants, Chemical Raw Materials, Intermediate, Excipients, Herbal extracts, Formulation of Chinese & Western Medicine. With abundant economic strength, the group has successfully developed to a pharmaceutical group enterprise wich intergrets operation of medicine & related products, processing & manufacturing, and importation & exportation together.
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JRC

India
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JRC

India
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Meglumine

About the Company : We commit to be a customer focused business and acknowledge that to be successful we have to make the opportunity offered by our clients work for them and for the future prosperity...

We commit to be a customer focused business and acknowledge that to be successful we have to make the opportunity offered by our clients work for them and for the future prosperity of JRC. The opportunity within JRC is to promote an open environment to explore knowledge, share thoughts in a transparent manner and maintain our commitments to all the stakeholders at large. JRC’s strength over 5 years is in science and technology that includes synthetic organic chemistry, process research, and scale-up from laboratory to commercial-scale along with quality and regulatory support.
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Meglumine

About the Company : Maisuriya Pharma Solutions is a research-driven & technology-oriented company. Continuous innovations & improvement are the lifeblood of our business. Our major focus is to offer p...

Maisuriya Pharma Solutions is a research-driven & technology-oriented company. Continuous innovations & improvement are the lifeblood of our business. Our major focus is to offer pharmaceutical solutions globally. Our core expertise: Development of processes and production of complex molecules for Lifesciences and Specialty Chemicals markets. We are committed to providing customers with products fulfilling customers’ needs and expectations. Maisuriya Pharma Solutions ensures Safety and Reliability with respect to regulations (sustainable development, ISO, GMP), and guarantees total confidentiality.
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N-Methyl-D-Glucamine

About the Company : We are working in this business since last 14 years, supplying chemicals of all Grades & Quality to our valued customers in major Industries, entirely to their satisfaction and at ...

We are working in this business since last 14 years, supplying chemicals of all Grades & Quality to our valued customers in major Industries, entirely to their satisfaction and at best possible prevailing rates. We have a very strong customer base as we are recommended by many institutions & traders by giving priority to purchase through us because of our high quality products at competitive & reasonable price.
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Meglumine

About the Company : Pramukh Pharmachem, a global supplier of active pharmaceutical ingredients, is Schedule-M certified and WHO-GMP compliant. Located on the Chhatral, Mehsana-Ahmedabad Highway in Guj...

Pramukh Pharmachem, a global supplier of active pharmaceutical ingredients, is Schedule-M certified and WHO-GMP compliant. Located on the Chhatral, Mehsana-Ahmedabad Highway in Gujarat, India, we have been delivering quality pharmaceuticals since 2017. We are dedicated to providing the highest quality medicines and adding effective value to the industry. Our commitment extends to researching globally significant chemical molecules, supported by our team of highly qualified professionals.
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API Reference Price

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KGAA","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"MERCK GROUP","customerCountry":"INDIA","quantity":"400.00","actualQuantity":"400","unit":"KGS","unitRateFc":"6325.7","totalValueFC":"30241.2","currency":"INR","unitRateINR":"6341.5","date":"30-Aug-2024","totalValueINR":"2536587.25","totalValueInUsd":"30241.2","indian_port":"Bombay Air","hs_no":"29221990","bill_no":"5332836","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"Frankfurter Strasse 250, 64293 Darmstadt,(BENEFICIARY MERCKFINANCIALSSERVICES GMBH) GERMANY","customerAddress":"50A , RING ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724956200,"product":"MEGLUMINE LOW IN ENDOTOXINS EMPROVE API PH EUR,CHP,JP,USP 20PCS X 25KG","address":"50A , RING ROAD,","city":"BANGALORE, KARNATAKA","supplier":"MERCK LIFE SCIENCE KGAA","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"MERCK GROUP","customerCountry":"INDIA","quantity":"500.00","actualQuantity":"500","unit":"KGS","unitRateFc":"6325.7","totalValueFC":"37801.5","currency":"INR","unitRateINR":"6341.5","date":"30-Aug-2024","totalValueINR":"3170734.07","totalValueInUsd":"37801.5","indian_port":"Bombay Air","hs_no":"29221990","bill_no":"5332836","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"Frankfurter Strasse 250, 64293 Darmstadt,(BENEFICIARY MERCKFINANCIALSSERVICES GMBH) GERMANY","customerAddress":"50A , RING ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724956200,"product":"MEGLUMINE LOW IN ENDOTOXINS EMPROVE API PH EUR,CHP,JP,USP 29PCS X 25KG","address":"50A , RING ROAD,","city":"BANGALORE, KARNATAKA","supplier":"MERCK LIFE SCIENCE KGAA","supplierCountry":"GERMANY","foreign_port":"FRANKFURT\/MAIN INT\\'L","customer":"MERCK GROUP","customerCountry":"INDIA","quantity":"725.00","actualQuantity":"725","unit":"KGS","unitRateFc":"6325.7","totalValueFC":"54812.2","currency":"INR","unitRateINR":"6341.5","date":"30-Aug-2024","totalValueINR":"4597564.4","totalValueInUsd":"54812.2","indian_port":"Bombay Air","hs_no":"29221990","bill_no":"5332836","productDescription":"API","marketType":"REGULATED MARKET","country":"GERMANY","selfForZScoreResived":"Pharma Grade","supplierPort":"FRANKFURT\/MAIN INT\\'L","supplierAddress":"Frankfurter Strasse 250, 64293 Darmstadt,(BENEFICIARY MERCKFINANCIALSSERVICES GMBH) GERMANY","customerAddress":"50A , RING ROAD,"}]
12-Jan-2021
30-Aug-2024
KGS
overview
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Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
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Average Price
(USD/KGS)
Number of Transactions

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