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Chemistry

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Also known as: Mephentermine sulfate, 6190-60-9 (sulfate), Mephentermine sodium, N,2-dimethyl-1-phenylpropan-2-amine,sulfuric acid,dihydrate;n,2-dimethyl-1-phenylpropan-2-amine,sulfuric acid,dihydrate, 2-propanamine, 2,n-dimethyl-1-phenyl-, sulfate, Mls002153976
Molecular Formula
C11H19NO4S
Molecular Weight
261.34  g/mol
InChI Key
NZKLHVGUPFNBFD-UHFFFAOYSA-N

Mephentermine Sulfate
A sympathomimetic agent with specificity for alpha-1 adrenergic receptors. It is used to maintain BLOOD PRESSURE in hypotensive states such as following SPINAL ANESTHESIA.
1 2D Structure

Mephentermine Sulfate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N,2-dimethyl-1-phenylpropan-2-amine;sulfuric acid
2.1.2 InChI
InChI=1S/C11H17N.H2O4S/c1-11(2,12-3)9-10-7-5-4-6-8-10;1-5(2,3)4/h4-8,12H,9H2,1-3H3;(H2,1,2,3,4)
2.1.3 InChI Key
NZKLHVGUPFNBFD-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC(C)(CC1=CC=CC=C1)NC.OS(=O)(=O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Mephentermine

2. Mephentermine Sulfate

3. Mephentermine Sulfate (2:1)

4. Sulfate, Mephentermine

2.2.2 Depositor-Supplied Synonyms

1. Mephentermine Sulfate

2. 6190-60-9 (sulfate)

3. Mephentermine Sodium

4. N,2-dimethyl-1-phenylpropan-2-amine,sulfuric Acid,dihydrate;n,2-dimethyl-1-phenylpropan-2-amine,sulfuric Acid,dihydrate

5. 2-propanamine, 2,n-dimethyl-1-phenyl-, Sulfate

6. Mls002153976

7. Spectrum1503250

8. Schembl6237301

9. Chembl1200996

10. Hms500l11

11. Hms1922m15

12. Hms2092p22

13. Hms2236o06

14. Hms3369h09

15. Pharmakon1600-01503250

16. Ccg-39977

17. Nsc758424

18. Ncgc00095030-01

19. Ncgc00095030-02

20. Smr001233313

21. Sr-05000001843

22. Sr-05000001843-1

2.3 Create Date
2006-03-07
3 Chemical and Physical Properties
Molecular Weight 261.34 g/mol
Molecular Formula C11H19NO4S
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass261.10347926 g/mol
Monoisotopic Mass261.10347926 g/mol
Topological Polar Surface Area95 Ų
Heavy Atom Count17
Formal Charge0
Complexity204
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Adrenergic alpha-1 Receptor Agonists

Compounds that bind to and activate ADRENERGIC ALPHA-1 RECEPTORS. (See all compounds classified as Adrenergic alpha-1 Receptor Agonists.)


Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


Vasoconstrictor Agents

Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)


API Reference Price

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22-Jan-2024
22-Jan-2024
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ABOUT THIS PAGE

Mephentermine Sulfate Manufacturers

A Mephentermine Sulfate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mephentermine Sulfate, including repackagers and relabelers. The FDA regulates Mephentermine Sulfate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mephentermine Sulfate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Mephentermine Sulfate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Mephentermine Sulfate Suppliers

A Mephentermine Sulfate supplier is an individual or a company that provides Mephentermine Sulfate active pharmaceutical ingredient (API) or Mephentermine Sulfate finished formulations upon request. The Mephentermine Sulfate suppliers may include Mephentermine Sulfate API manufacturers, exporters, distributors and traders.

click here to find a list of Mephentermine Sulfate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Mephentermine Sulfate WC

A Mephentermine Sulfate written confirmation (Mephentermine Sulfate WC) is an official document issued by a regulatory agency to a Mephentermine Sulfate manufacturer, verifying that the manufacturing facility of a Mephentermine Sulfate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Mephentermine Sulfate APIs or Mephentermine Sulfate finished pharmaceutical products to another nation, regulatory agencies frequently require a Mephentermine Sulfate WC (written confirmation) as part of the regulatory process.

click here to find a list of Mephentermine Sulfate suppliers with Written Confirmation (WC) on PharmaCompass.

Mephentermine Sulfate GMP

Mephentermine Sulfate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Mephentermine Sulfate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mephentermine Sulfate GMP manufacturer or Mephentermine Sulfate GMP API supplier for your needs.

Mephentermine Sulfate CoA

A Mephentermine Sulfate CoA (Certificate of Analysis) is a formal document that attests to Mephentermine Sulfate's compliance with Mephentermine Sulfate specifications and serves as a tool for batch-level quality control.

Mephentermine Sulfate CoA mostly includes findings from lab analyses of a specific batch. For each Mephentermine Sulfate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Mephentermine Sulfate may be tested according to a variety of international standards, such as European Pharmacopoeia (Mephentermine Sulfate EP), Mephentermine Sulfate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mephentermine Sulfate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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