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ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 Listed Suppliers

1 API Suppliers
1 Listed Suppliers

DEVELOPMENTS

13 Drugs in Development

13 Drugs in Development

FINISHED DOSAGE FORMULATIONS

18 FDF Dossiers, 2 FDA Orange Book, 5 Europe, 3 Canada, 8 Australia

18 FDF Dossiers
2 FDA Orange Book
5 Europe
3 Canada
8 Australia

RELATED EXCIPIENT COMPANIES

1 Nanjing Well Pharmaceutical, 1 Pfanstiehl, 3 Actylis, 1 BASF, 4 Gangwal Chemicals, 1 Nanjing Bold Chemical, 6 Seppic

relatedExcipients
1 Nanjing Well Pharmaceutical
1 Pfanstiehl
3 Actylis
1 BASF
4 Gangwal Chemicals
1 Nanjing Bold Chemical
6 Seppic

EXCIPIENTS BY APPLICATIONS

10 Solubilizers, 6 Parenteral, 4 Thickeners and Stabilizers, 3 Topical, 3 Emulsifying Agents, 2 Film Formers & Plasticizers, 2 Taste Masking, 2 Surfactant & Foaming Agents, 2 Coating Systems & Additives, 1 API Stability Enhancers, 1 Co-Processed Excipients, 1 Direct Compression, 1 Rheology Modifiers

excipientsByApplications
10 Solubilizers
6 Parenteral
4 Thickeners and Stabilizers
3 Topical
3 Emulsifying Agents
2 Film Formers & Plasticizers
2 Taste Masking
2 Surfactant & Foaming Agents
2 Coating Systems & Additives
1 API Stability Enhancers
1 Co-Processed Excipients
1 Direct Compression
1 Rheology Modifiers

DIGITAL CONTENT

4 DATA COMPILATION #PharmaFlow, 1 STOCK RECAP #PipelineProspector, 77 NEWS #PharmaBuzz

media
4 DATA COMPILATION #PharmaFlow
1 STOCK RECAP #PipelineProspector
77 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 4 Finished Drug Prices, 8 Annual Reports

globalSalesInformation
1 US Medicaid Prescriptions
4 Finished Drug Prices
8 Annual Reports

MARKET PLACE

1 APIs, 1 FDF Dossiers

marketPlace
1 APIs
1 FDF Dossiers

PATENTS & EXCLUSIVITIES

1 Health Canada Patents

patents
1 Health Canada Patents

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

13DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

193,350,671

Annual Reports (USD Million)

8,775

Finished Drug Prices

17 RELATED EXCIPIENT COMPANIES

38EXCIPIENTS BY APPLICATIONS

Chemistry

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Also known as:

Molecular Formula

C₄₂H₆₆O₁₂

Molecular Weight

763.0 g/mol

InChI Key

PMOOKBAYUNEHOF-IKHMJLPLSA-N

1 2D Structure

Mepolizumab

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S,3S,4S,5R,6R)-6-[[(4aR,6aR,6bS,8aS,14aR,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,13,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-4-[(1R,2R,3S,4R)-2,3,4-trihydroxycyclohexyl]oxyoxane-2-carboxylic acid

2.1.2 InChI

InChI=1S/C42H66O12/c1-37(2)16-18-42(36(50)51)19-17-40(6)21(22(42)20-37)8-11-26-39(5)14-13-27(38(3,4)25(39)12-15-41(26,40)7)53-35-31(47)32(30(46)33(54-35)34(48)49)52-24-10-9-23(43)28(44)29(24)45/h23-33,35,43-47H,8-20H2,1-7H3,(H,48,49)(H,50,51)/t23-,24-,25+,26-,27?,28+,29+,30+,31-,32+,33+,35-,39+,40-,41-,42+/m1/s1

2.1.3 InChI Key

PMOOKBAYUNEHOF-IKHMJLPLSA-N

2.1.4 Canonical SMILES

CC1(CCC2(CCC3(C(=C2C1)CCC4C3(CCC5C4(CCC(C5(C)C)OC6C(C(C(C(O6)C(=O)O)O)OC7CCC(C(C7O)O)O)O)C)C)C)C(=O)O)C

2.1.5 Isomeric SMILES

C[C@]12CCC(C([C@@H]1CC[C@@]3([C@@H]2CCC4=C5CC(CC[C@@]5(CC[C@]43C)C(=O)O)(C)C)C)(C)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O[C@@H]7CC[C@H]([C@@H]([C@H]7O)O)O)O

2.2 Create Date

2012-02-15

3 Chemical and Physical Properties

Molecular Formula	C₄₂H₆₆O₁₂
Molecular Weight	763.0 g/mol
XLogP3	5.1
Hydrogen Bond Donor Count	7
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	6
Exact Mass	762.45542754 g/mol
Monoisotopic Mass	762.45542754 g/mol
Topological Polar Surface Area	203 Å²
Heavy Atom Count	54
Formal Charge	0
Complexity	1530
Isotope Atom Count	0
Defined Atom Stereocenter Count	15
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

API SUPPLIERS

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Listed Suppliers

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Drugs in Development

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FDF Dossiers

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FDA Orange Book

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Europe

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Canada

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Australia

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Excipients by Applications

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Solubilizers

Parenteral

Thickeners and Stabilizers

Topical

Emulsifying Agents

Film Formers & Plasticizers

Taste Masking

Surfactant & Foaming Agents

Coating Systems & Additives

API Stability Enhancers

Co-Processed Excipients

Direct Compression

Rheology Modifiers

Digital Content

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DATA COMPILATION #PharmaFlow

STOCK RECAP #PipelineProspector

NEWS #PharmaBuzz

Global Sales Information

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US Medicaid Prescriptions

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Finished Drug Prices

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Annual Reports

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Market Place

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APIs

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FDF DOSSIERS

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Patents & EXCLUSIVITIES

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Health Canada Patents

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ABOUT THIS PAGE

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Mepolizumab

ACCESS ALL DATA

Browse all information

CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers

1 Listed Suppliers

DEVELOPMENTS

13 Drugs in Development

FINISHED DOSAGE FORMULATIONS

18 FDF Dossiers

2 FDA Orange Book

5 Europe

3 Canada

8 Australia

RELATED EXCIPIENT COMPANIES

1 Nanjing Well Pharmaceutical

1 Pfanstiehl

3 Actylis

1 BASF

4 Gangwal Chemicals

1 Nanjing Bold Chemical

6 Seppic

EXCIPIENTS BY APPLICATIONS

10 Solubilizers

6 Parenteral

4 Thickeners and Stabilizers

3 Topical

3 Emulsifying Agents

2 Film Formers & Plasticizers

2 Taste Masking

2 Surfactant & Foaming Agents

2 Coating Systems & Additives

1 API Stability Enhancers

1 Co-Processed Excipients

1 Direct Compression

1 Rheology Modifiers

DIGITAL CONTENT

4 DATA COMPILATION #PharmaFlow

1 STOCK RECAP #PipelineProspector

77 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

4 Finished Drug Prices

8 Annual Reports

MARKET PLACE

1 APIs

1 FDF Dossiers

PATENTS & EXCLUSIVITIES

1 Health Canada Patents

ACTIVE PHARMA INGREDIENTS

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

13DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

PATENTS & EXCLUSIVITIES

DIGITAL CONTENT

GLOBAL SALES INFORMATION

17 RELATED EXCIPIENT COMPANIES

38EXCIPIENTS BY APPLICATIONS

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