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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

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CEP/COS

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NDC API

NDC API

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NDC API

API REF. PRICE (USD/KG)

$
$ 0

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South Africa

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Chemistry

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Also known as:
Molecular Formula
C42H66O12
Molecular Weight
763.0  g/mol
InChI Key
PMOOKBAYUNEHOF-IKHMJLPLSA-N

Mepolizumab
1 2D Structure

Mepolizumab

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S,3S,4S,5R,6R)-6-[[(4aR,6aR,6bS,8aS,14aR,14bR)-8a-carboxy-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,13,14,14a-tetradecahydropicen-3-yl]oxy]-3,5-dihydroxy-4-[(1R,2R,3S,4R)-2,3,4-trihydroxycyclohexyl]oxyoxane-2-carboxylic acid
2.1.2 InChI
InChI=1S/C42H66O12/c1-37(2)16-18-42(36(50)51)19-17-40(6)21(22(42)20-37)8-11-26-39(5)14-13-27(38(3,4)25(39)12-15-41(26,40)7)53-35-31(47)32(30(46)33(54-35)34(48)49)52-24-10-9-23(43)28(44)29(24)45/h23-33,35,43-47H,8-20H2,1-7H3,(H,48,49)(H,50,51)/t23-,24-,25+,26-,27?,28+,29+,30+,31-,32+,33+,35-,39+,40-,41-,42+/m1/s1
2.1.3 InChI Key
PMOOKBAYUNEHOF-IKHMJLPLSA-N
2.1.4 Canonical SMILES
CC1(CCC2(CCC3(C(=C2C1)CCC4C3(CCC5C4(CCC(C5(C)C)OC6C(C(C(C(O6)C(=O)O)O)OC7CCC(C(C7O)O)O)O)C)C)C)C(=O)O)C
2.1.5 Isomeric SMILES
C[C@]12CCC(C([C@@H]1CC[C@@]3([C@@H]2CCC4=C5CC(CC[C@@]5(CC[C@]43C)C(=O)O)(C)C)C)(C)C)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)C(=O)O)O)O[C@@H]7CC[C@H]([C@@H]([C@H]7O)O)O)O
2.2 Create Date
2012-02-15
3 Chemical and Physical Properties
Molecular Weight 763.0 g/mol
Molecular Formula C42H66O12
XLogP35.1
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count12
Rotatable Bond Count6
Exact Mass762.45542754 g/mol
Monoisotopic Mass762.45542754 g/mol
Topological Polar Surface Area203 Ų
Heavy Atom Count54
Formal Charge0
Complexity1530
Isotope Atom Count0
Defined Atom Stereocenter Count15
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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