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Chemistry

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Also known as: 129-16-8, Merbromina, Mercury dibromofluorescein disodium salt, Disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;hydrate, Disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;tetrahydrate, Mfcd00013081
Molecular Formula
C20H9Br2HgNa2O6
Molecular Weight
751.7  g/mol
InChI Key
KQSRXDXJGUJRKE-UHFFFAOYSA-L

Merbromin
A once-popular mercury containing topical antiseptic.
1 2D Structure

Merbromin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;hydrate
2.1.2 InChI
InChI=1S/C20H9Br2O5.Hg.2Na.H2O/c21-13-5-11-17(7-15(13)23)27-18-8-16(24)14(22)6-12(18)19(11)9-3-1-2-4-10(9)20(25)26;;;;/h1-7,24H,(H,25,26);;;;1H2/q;;2*+1;/p-2
2.1.3 InChI Key
KQSRXDXJGUJRKE-UHFFFAOYSA-L
2.1.4 Canonical SMILES
C1=CC=C(C(=C1)C2=C3C=C(C(=O)C=C3OC4=C(C(=C(C=C24)Br)[O-])[Hg])Br)C(=O)[O-].O.[Na+].[Na+]
2.2 Synonyms
2.2.1 MeSH Synonyms

1. 2,7 Dibromo 4 Hydroxymercurifluoresceine

2. 2,7-dibromo-4-hydroxymercurifluoresceine

3. Merbromine

4. Mercurochrome

5. Mercury, (2',7'-dibromo-3',6'-dihydroxy-3-oxospiro(isobenzofuran-1(3h),9'-(9h)xanthen)-4'-yl)hydroxy-, Disodium Salt

2.2.2 Depositor-Supplied Synonyms

1. 129-16-8

2. Merbromina

3. Mercury Dibromofluorescein Disodium Salt

4. Disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;hydrate

5. Disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;tetrahydrate

6. Mfcd00013081

7. Cinfacromin

8. Merbromino

9. Mercuriocromo

10. Supercrome

11. Sodium Merbromin

12. Sodium Mercurescein

13. Mercurochrome (tn)

14. Merbromin N.f Xii

15. Schembl25312

16. Spectrum1500637

17. Chebi:6763

18. Hms501e17

19. Dtxsid701015061

20. Hms1921m15

21. Hms2092e12

22. Bcp24664

23. Ccg-39726

24. Akos015903744

25. Db13392

26. Ncgc00094822-01

27. Ncgc00094822-02

28. D00861

29. Mercury Dibromofluorescein Disodium Salt, Practical Grade, Crystalline

30. 15015-80-2

31. Disodium [2,7-dibromo-9-(2-carboxylatophenyl)-6-oxido-3-oxo-3h-xanthen-5-yl](hydroxy)mercury

32. Sodium (2,7-dibromo-9-(2-carboxylatophenyl)-6-oxido-3-oxo-3h-xanthen-5-yl)(hydroxy)mercury

2.3 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 751.7 g/mol
Molecular Formula C20H9Br2HgNa2O6
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass752.82472 g/mol
Monoisotopic Mass750.82677 g/mol
Topological Polar Surface Area90.5 Ų
Heavy Atom Count31
Formal Charge0
Complexity801
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count4
4 Pharmacology and Biochemistry
4.1 ATC Code

D - Dermatologicals

D08 - Antiseptics and disinfectants

D08A - Antiseptics and disinfectants

D08AK - Mercurial products

D08AK04 - Merbromin


API Reference Price

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18-Jan-2021
18-Dec-2024
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API | Excipient name

Merbromin

Synonyms

129-16-8, Merbromina, Mercury dibromofluorescein disodium salt, Disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;hydrate, Disodium;[2,7-dibromo-9-(2-carboxylatophenyl)-3-oxido-6-oxoxanthen-4-yl]mercury;tetrahydrate, Mfcd00013081

Cas Number

129-16-8

About Merbromin

A once-popular mercury containing topical antiseptic.

Merbromin Manufacturers

A Merbromin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Merbromin, including repackagers and relabelers. The FDA regulates Merbromin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Merbromin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Merbromin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Merbromin Suppliers

A Merbromin supplier is an individual or a company that provides Merbromin active pharmaceutical ingredient (API) or Merbromin finished formulations upon request. The Merbromin suppliers may include Merbromin API manufacturers, exporters, distributors and traders.

click here to find a list of Merbromin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Merbromin GMP

Merbromin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Merbromin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Merbromin GMP manufacturer or Merbromin GMP API supplier for your needs.

Merbromin CoA

A Merbromin CoA (Certificate of Analysis) is a formal document that attests to Merbromin's compliance with Merbromin specifications and serves as a tool for batch-level quality control.

Merbromin CoA mostly includes findings from lab analyses of a specific batch. For each Merbromin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Merbromin may be tested according to a variety of international standards, such as European Pharmacopoeia (Merbromin EP), Merbromin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Merbromin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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