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Chemistry

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Also known as: Meropenem & vaborbactam, Meropenem + vaborbactam, 2031124-72-6, Vabomere, Meropenem / vaborbactam, Meropenem and vaborbactam
Molecular Formula
C29H41BN4O10S2
Molecular Weight
680.6  g/mol
InChI Key
SDJYWZHQLNEXKV-SSHSFQATSA-N

Meropenem And Vaborbactam
1 2D Structure

Meropenem And Vaborbactam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(4R,5S,6S)-3-[(3S,5S)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;2-[(3R,6S)-2-hydroxy-3-[(2-thiophen-2-ylacetyl)amino]oxaborinan-6-yl]acetic acid
2.1.2 InChI
InChI=1S/C17H25N3O5S.C12H16BNO5S/c1-7-12-11(8(2)21)16(23)20(12)13(17(24)25)14(7)26-9-5-10(18-6-9)15(22)19(3)4;15-11(7-9-2-1-5-20-9)14-10-4-3-8(6-12(16)17)19-13(10)18/h7-12,18,21H,5-6H2,1-4H3,(H,24,25);1-2,5,8,10,18H,3-4,6-7H2,(H,14,15)(H,16,17)/t7-,8-,9+,10+,11-,12-;8-,10-/m10/s1
2.1.3 InChI Key
SDJYWZHQLNEXKV-SSHSFQATSA-N
2.1.4 Canonical SMILES
B1(C(CCC(O1)CC(=O)O)NC(=O)CC2=CC=CS2)O.CC1C2C(C(=O)N2C(=C1SC3CC(NC3)C(=O)N(C)C)C(=O)O)C(C)O
2.1.5 Isomeric SMILES
B1([C@H](CC[C@H](O1)CC(=O)O)NC(=O)CC2=CC=CS2)O.C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1S[C@H]3C[C@H](NC3)C(=O)N(C)C)C(=O)O)[C@@H](C)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Meropenem - Vaborbactam

2. Meropenem And Vaborbactam

3. Meropenem Vaborbactam Drug Combination

4. Vabomere

2.2.2 Depositor-Supplied Synonyms

1. Meropenem & Vaborbactam

2. Meropenem + Vaborbactam

3. 2031124-72-6

4. Vabomere

5. Meropenem / Vaborbactam

6. Meropenem And Vaborbactam

7. Meropenem Mixture With Vaborbactam

8. (4r,5s,6s)-3-[(3s,5s)-5-(dimethylcarbamoyl)pyrrolidin-3-yl]sulfanyl-6-[(1r)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic Acid;2-[(3r,6s)-2-hydroxy-3-[(2-thiophen-2-ylacetyl)amino]oxaborinan-6-yl]acetic Acid

2.3 Create Date
2014-12-31
3 Chemical and Physical Properties
Molecular Weight 680.6 g/mol
Molecular Formula C29H41BN4O10S2
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count13
Rotatable Bond Count10
Exact Mass680.2357160 g/mol
Monoisotopic Mass680.2357160 g/mol
Topological Polar Surface Area260 Ų
Heavy Atom Count46
Formal Charge0
Complexity1050
Isotope Atom Count0
Defined Atom Stereocenter Count8
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 1  
Drug NameVABOMERE
Active IngredientMEROPENEM; VABORBACTAM
CompanyREMPEX PHARMS (Application Number: N209776. Patents: 8680136, 9694025)

5 Pharmacology and Biochemistry
5.1 ATC Code

J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01D - Other beta-lactam antibacterials

J01DH - Carbapenems

J01DH52 - Meropenem and vaborbactam


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ABOUT THIS PAGE

Meropenem And Vaborbactam Manufacturers

A Meropenem And Vaborbactam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Meropenem And Vaborbactam, including repackagers and relabelers. The FDA regulates Meropenem And Vaborbactam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Meropenem And Vaborbactam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Meropenem And Vaborbactam Suppliers

A Meropenem And Vaborbactam supplier is an individual or a company that provides Meropenem And Vaborbactam active pharmaceutical ingredient (API) or Meropenem And Vaborbactam finished formulations upon request. The Meropenem And Vaborbactam suppliers may include Meropenem And Vaborbactam API manufacturers, exporters, distributors and traders.

Meropenem And Vaborbactam GMP

Meropenem And Vaborbactam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Meropenem And Vaborbactam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Meropenem And Vaborbactam GMP manufacturer or Meropenem And Vaborbactam GMP API supplier for your needs.

Meropenem And Vaborbactam CoA

A Meropenem And Vaborbactam CoA (Certificate of Analysis) is a formal document that attests to Meropenem And Vaborbactam's compliance with Meropenem And Vaborbactam specifications and serves as a tool for batch-level quality control.

Meropenem And Vaborbactam CoA mostly includes findings from lab analyses of a specific batch. For each Meropenem And Vaborbactam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Meropenem And Vaborbactam may be tested according to a variety of international standards, such as European Pharmacopoeia (Meropenem And Vaborbactam EP), Meropenem And Vaborbactam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Meropenem And Vaborbactam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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