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Chemistry

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Also known as: Irl790, Irl-790, Hd4qv8gx26, 1403894-72-3, N-[2-(3-fluoro-5-methylsulfonylphenoxy)ethyl]propan-1-amine, 1-propanamine, n-(2-(3-fluoro-5-(methylsulfonyl)phenoxy)ethyl)-
Molecular Formula
C12H18FNO3S
Molecular Weight
275.34  g/mol
InChI Key
OSBPYFBXSLJHCR-UHFFFAOYSA-N
FDA UNII
HD4QV8GX26

Mesdopetam
Mesdopetam is under investigation in clinical trial NCT04435431 (A Clinical Study of Mesdopetam in Patients With Parkinson's Disease Experiencing Levodopa Induced Dyskinesia).
1 2D Structure

Mesdopetam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
N-[2-(3-fluoro-5-methylsulfonylphenoxy)ethyl]propan-1-amine
2.1.2 InChI
InChI=1S/C12H18FNO3S/c1-3-4-14-5-6-17-11-7-10(13)8-12(9-11)18(2,15)16/h7-9,14H,3-6H2,1-2H3
2.1.3 InChI Key
OSBPYFBXSLJHCR-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCNCCOC1=CC(=CC(=C1)S(=O)(=O)C)F
2.2 Other Identifiers
2.2.1 UNII
HD4QV8GX26
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Irl790

2. N-(2-(3-fluoro-5-methylsulfonylphenoxy)ethyl)propan-1-amine

2.3.2 Depositor-Supplied Synonyms

1. Irl790

2. Irl-790

3. Hd4qv8gx26

4. 1403894-72-3

5. N-[2-(3-fluoro-5-methylsulfonylphenoxy)ethyl]propan-1-amine

6. 1-propanamine, N-(2-(3-fluoro-5-(methylsulfonyl)phenoxy)ethyl)-

7. Mesdopetam [inn]

8. Unii-hd4qv8gx26

9. Mesdopetam [who-dd]

10. Chembl4594447

11. Schembl13732678

12. Gtpl10811

13. Hy-109150

14. Cs-0115974

15. N-[2-(3-fluoro-5-methylsulfonyl-phenoxy)ethyl]propan-1-amine

16. N-{2-[3-fluoro-5-(methylsulfonyl)phenoxy]ethyl}-n-propylamine

2.4 Create Date
2013-03-21
3 Chemical and Physical Properties
Molecular Weight 275.34 g/mol
Molecular Formula C12H18FNO3S
XLogP31.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count7
Exact Mass275.09914277 g/mol
Monoisotopic Mass275.09914277 g/mol
Topological Polar Surface Area63.8 Ų
Heavy Atom Count18
Formal Charge0
Complexity329
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Dopamine Antagonists

Drugs that bind to but do not activate DOPAMINE RECEPTORS, thereby blocking the actions of dopamine or exogenous agonists. Many drugs used in the treatment of psychotic disorders (ANTIPSYCHOTIC AGENTS) are dopamine antagonists, although their therapeutic effects may be due to long-term adjustments of the brain rather than to the acute effects of blocking dopamine receptors. Dopamine antagonists have been used for several other clinical purposes including as ANTIEMETICS, in the treatment of Tourette syndrome, and for hiccup. Dopamine receptor blockade is associated with NEUROLEPTIC MALIGNANT SYNDROME. (See all compounds classified as Dopamine Antagonists.)


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ABOUT THIS PAGE

Mesdopetam Manufacturers

A Mesdopetam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mesdopetam, including repackagers and relabelers. The FDA regulates Mesdopetam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mesdopetam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Mesdopetam Suppliers

A Mesdopetam supplier is an individual or a company that provides Mesdopetam active pharmaceutical ingredient (API) or Mesdopetam finished formulations upon request. The Mesdopetam suppliers may include Mesdopetam API manufacturers, exporters, distributors and traders.

Mesdopetam GMP

Mesdopetam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Mesdopetam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mesdopetam GMP manufacturer or Mesdopetam GMP API supplier for your needs.

Mesdopetam CoA

A Mesdopetam CoA (Certificate of Analysis) is a formal document that attests to Mesdopetam's compliance with Mesdopetam specifications and serves as a tool for batch-level quality control.

Mesdopetam CoA mostly includes findings from lab analyses of a specific batch. For each Mesdopetam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Mesdopetam may be tested according to a variety of international standards, such as European Pharmacopoeia (Mesdopetam EP), Mesdopetam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mesdopetam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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