DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

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Valsynthese, part of the SSE Group, is a CDMO focused on highly energetic and highly hazardous chemistry.

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CHEMISTRY
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ACTIVE PHARMA INGREDIENTS

12 API Suppliers, 8 USDMF, 2 CEP/COS, 1 JDMF, 3 EU WC, 3 NDC API, 5 Listed Suppliers, $ API Reference Price

12 API Suppliers
8 USDMF
2 CEP/COS
1 JDMF
3 EU WC
3 NDC API
5 Listed Suppliers
$ API Reference Price

FINISHED DOSAGE FORMULATIONS

49 FDF Dossiers, 14 FDA Orange Book, 18 Europe, 3 Canada, 4 Australia, 3 South Africa, 7 Listed Dossiers

49 FDF Dossiers
14 FDA Orange Book
18 Europe
3 Canada
4 Australia
3 South Africa
7 Listed Dossiers

RELATED EXCIPIENT COMPANIES

5 SPI Pharma, 2 Seqens, 2 DKSH, 3 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 10 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 4 Actylis, 3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 17 BASF, 2 DFE Pharma, 2 Finar, 6 Gangwal Chemicals, 1 Ideal Cures Pvt Ltd, 2 Ingredion Pharma Solutions, 6 Kerry, 8 Microlex e.U, 2 Nomisma Healthcare, 1 Novo Excipients, 2 Pharmatrans-Sanaq, 3 Pluviaendo, 2 Prachin Chemical, 15 Roquette, 1 Seppic, 3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 8 Sigachi Industries, 2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

40 Fillers, Diluents & Binders, 24 Direct Compression, 16 Thickeners and Stabilizers, 13 Controlled & Modified Release, 13 Co-Processed Excipients, 12 Granulation, 11 Solubilizers, 11 Coating Systems & Additives, 10 Lubricants & Glidants, 10 Disintegrants & Superdisintegrants, 9 Topical, 6 Taste Masking, 5 Film Formers & Plasticizers, 5 Chewable & Orodispersible Aids, 5 Parenteral, 2 Coloring Agents, 1 Rheology Modifiers, 1 Emulsifying Agents

excipientsByApplications
40 Fillers, Diluents & Binders
24 Direct Compression
16 Thickeners and Stabilizers
13 Controlled & Modified Release
13 Co-Processed Excipients
12 Granulation
11 Solubilizers
11 Coating Systems & Additives
10 Lubricants & Glidants
10 Disintegrants & Superdisintegrants
9 Topical
6 Taste Masking
5 Film Formers & Plasticizers
5 Chewable & Orodispersible Aids
5 Parenteral
2 Coloring Agents
1 Rheology Modifiers
1 Emulsifying Agents

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow, 1 NEWS #PharmaBuzz

media
2 DATA COMPILATION #PharmaFlow
1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions, 10 Finished Drug Prices

globalSalesInformation
1 US Medicaid Prescriptions
10 Finished Drug Prices

MARKET PLACE

7 APIs, 1 FDF Dossiers

marketPlace
7 APIs
1 FDF Dossiers

REF. STANDARDS & IMPURITIES

3 EDQM , 3 USP , 3 Others

otherSolutions
3 EDQM
3 USP
3 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 754

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

3,502

Annual Reports (USD Million)

Finished Drug Prices

114 RELATED EXCIPIENT COMPANIES

194EXCIPIENTS BY APPLICATIONS

Chemistry

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Click the button for full data set

Also known as: 19767-45-4, Sodium 2-mercaptoethanesulfonate, Uromitexan, Mesnex, Mitexan, Mistabron

Molecular Formula

C₂H₅NaO₃S₂

Molecular Weight

164.18 g/mol

InChI Key

XOGTZOOQQBDUSI-UHFFFAOYSA-M

FDA UNII

NR7O1405Q9

A sulfhydryl compound used to prevent urothelial toxicity by inactivating metabolites from ANTINEOPLASTIC AGENTS, such as IFOSFAMIDE or CYCLOPHOSPHAMIDE.

1 2D Structure

Mesna

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

sodium;2-sulfanylethanesulfonate

2.1.2 InChI

InChI=1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1

2.1.3 InChI Key

XOGTZOOQQBDUSI-UHFFFAOYSA-M

2.1.4 Canonical SMILES

C(CS(=O)(=O)[O-])S.[Na+]

2.2 Other Identifiers

2.2.1 UNII

NR7O1405Q9

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 2 Mercaptoethanesulfonate

2. 2-mercaptoethanesulfonate

3. 2-mercaptoethanesulphonate, Sodium

4. Asta D 7093

5. Asta-d 7093

6. Astad 7093

7. Coenzyme M

8. Ethanesulfonic Acid, 2-mercapto-, Monosodium Salt

9. Mesna Cell

10. Mesna-cell

11. Mesnex

12. Mesnum

13. Mistabron

14. Mistabronco

15. Mitexan

16. Mucofluid

17. Sodium 2-mercaptoethanesulphonate

18. Ucb 3983

19. Ucb-3983

20. Ucb3983

21. Uromitexan

22. Ziken

2.3.2 Depositor-Supplied Synonyms

1. 19767-45-4

2. Sodium 2-mercaptoethanesulfonate

3. Uromitexan

4. Mesnex

5. Mitexan

6. Mistabron

7. Mesnum

8. 2-mercaptoethanesulfonic Acid Sodium Salt

9. Mistabronco

10. Sodium 2-mercaptoethane Sulfonate

11. Ethanesulfonic Acid, 2-mercapto-, Monosodium Salt

12. Coenzyme M Sodium Salt

13. Sodium;2-sulfanylethanesulfonate

14. 2-mercaptoethanesulfonate, Sodium

15. 2-mercaptoethanesulfonic Acid Sodium

16. Sodium 2-mercaptoethanesulfonate;mesnum

17. Sodium 2-sulfanylethane-1-sulfonate

18. D 7093

19. D-7093

20. Nr7o1405q9

21. Nsc-113891

22. Ncgc00181166-01

23. Dsstox_cid_809

24. Dsstox_rid_75800

25. Dsstox_gsid_20809

26. Mesnum [inn-latin]

27. Smr000059219

28. Cas-19767-45-4

29. Natrium 2-mercaptoethansulfonat

30. Ccris 3712

31. 2-mercaptoethane Sulfonate Sodium

32. Sodium 2-mercaptoethanesulphonate

33. Einecs 243-285-9

34. Nsc 113891

35. Unii-nr7o1405q9

36. 2-mercapto-ethan-sulfonsaeure, Natrium-salz

37. 2-mercaptoethanesulfonic Acid Monosodium Salt

38. Mesna [usan:usp:inn:ban]

39. Uromitexan (tn)

40. Sodium 2-mercaptoethane-1-sulfonate

41. Mesnex (tn)

42. Mfcd00007535

43. Prestwick_1005

44. Mesna [vandf]

45. Mesna [usan]

46. Spectrum2_000752

47. Spectrum3_001483

48. Spectrum4_000041

49. Spectrum5_001174

50. Mesna [inn]

51. Mesna [jan]

52. Mesna [who-dd]

53. Mesna [mart.]

54. Mesna [mi]

55. Mesna (jan/usp/inn)

56. Chembl975

57. Schembl7993

58. Mesna (uromitexan, Mesnex)

59. Mesna [orange Book]

60. Kbiogr_000501

61. Mesna [ep Monograph]

62. Mesna [usp Impurity]

63. Mls001074691

64. Mls001333251

65. Mls001333252

66. Mesna [usp Monograph]

67. Spectrum1502014

68. Sodium2-mercaptoethanesulfonate

69. Spbio_000764

70. Dtxsid1020809

71. Chebi:31824

72. Hms502f17

73. Kbio3_002565

74. Hms1921d10

75. Hms2092n09

76. Hms2236l05

77. Hms3259d13

78. Hms3372m11

79. Hms3655m06

80. Hms3715h05

81. Sodium, 2-mercapto-ethanesulfonate

82. Bcp14384

83. Tox21_112767

84. Tox21_200863

85. Bdbm50247978

86. Ccg-40134

87. S1735

88. Akos006220661

89. Akos015960755

90. Tox21_112767_1

91. Ac-6011

92. Cs-1364

93. Nc00648

94. Ncgc00094939-01

95. Ncgc00094939-02

96. Ncgc00178318-04

97. Ncgc00258417-01

98. Sodium 2-sulphanylethanesulphonate

99. 2-mercaptoethanesulphonic Acid Sodium Salt

100. As-13260

101. Hy-13679

102. Db-044962

103. A8469

104. M0913

105. Sw199618-2

106. En300-49858

107. D01459

108. Ab01274734-01

109. Q424997

110. W-60283

111. Q-201713

112. 3-aminooxy-n-propyl(dimethyl-t-butylsilyl)ether

113. Z1741968275

2.4 Create Date

2008-02-05

3 Chemical and Physical Properties

Molecular Formula	C₂H₅NaO₃S₂
Molecular Weight	164.18 g/mol
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	163.95778065 g/mol
Monoisotopic Mass	163.95778065 g/mol
Topological Polar Surface Area	66.6 Å²
Heavy Atom Count	8
Formal Charge	0
Complexity	123
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Drug and Medication Information

4.1 Drug Information

1 of 4
Drug Name	Mesna
PubMed Health	Mesna
Drug Classes	Hemorrhagic Cystitis Inhibitor
Drug Label	Mesna is a detoxifying agent to inhibit the hemorrhagic cystitis induced by ifosfamide. The active ingredient mesna is a synthetic sulfhydryl compound designated as sodium-2-mercaptoethane sulfonate with a molecular formula of C2H5NaO3S2 and a molecu...
Active Ingredient	Mesna
Dosage Form	Injectable
Route	injection; Intravenous
Strength	1g/10ml; 100mg/ml
Market Status	Prescription
Company	Teva Pharms Usa; Fresenius Kabi Usa; Mylan Institutional; Sagent Pharms; Eurohlth Intl; Agila Speclts

2 of 4
Drug Name	Mesnex
PubMed Health	Mesna (By mouth)
Drug Classes	Hemorrhagic Cystitis Inhibitor
Drug Label	Mesna is a detoxifying agent to inhibit the hemorrhagic cystitis induced by ifosfamide (IFEX). The active ingredient mesna is a synthetic sulfhydryl compound designated as sodium-2-mercaptoethane sulfonate with a molecular formula of C2H5NaO3S2 and a...
Active Ingredient	Mesna
Dosage Form	Tablet; Injectable
Route	Oral; Intravenous
Strength	400mg; 100mg/ml
Market Status	Prescription
Company	Baxter Hlthcare

3 of 4
Drug Name	Mesna
PubMed Health	Mesna
Drug Classes	Hemorrhagic Cystitis Inhibitor
Drug Label	Mesna is a detoxifying agent to inhibit the hemorrhagic cystitis induced by ifosfamide. The active ingredient mesna is a synthetic sulfhydryl compound designated as sodium-2-mercaptoethane sulfonate with a molecular formula of C2H5NaO3S2 and a molecu...
Active Ingredient	Mesna
Dosage Form	Injectable
Route	injection; Intravenous
Strength	1g/10ml; 100mg/ml
Market Status	Prescription
Company	Teva Pharms Usa; Fresenius Kabi Usa; Mylan Institutional; Sagent Pharms; Eurohlth Intl; Agila Speclts

4 of 4
Drug Name	Mesnex
PubMed Health	Mesna (By mouth)
Drug Classes	Hemorrhagic Cystitis Inhibitor
Drug Label	Mesna is a detoxifying agent to inhibit the hemorrhagic cystitis induced by ifosfamide (IFEX). The active ingredient mesna is a synthetic sulfhydryl compound designated as sodium-2-mercaptoethane sulfonate with a molecular formula of C2H5NaO3S2 and a...
Active Ingredient	Mesna
Dosage Form	Tablet; Injectable
Route	Oral; Intravenous
Strength	400mg; 100mg/ml
Market Status	Prescription
Company	Baxter Hlthcare

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Protective Agents

Synthetic or natural substances which are given to prevent a disease or disorder or are used in the process of treating a disease or injury due to a poisonous agent. (See all compounds classified as Protective Agents.)

5.2 FDA Pharmacological Classification

5.2.1 Pharmacological Classes

Cytoprotective Agent [EPC]

5.3 ATC Code

R - Respiratory system

R05 - Cough and cold preparations

R05C - Expectorants, excl. combinations with cough suppressants

R05CB - Mucolytics

R05CB05 - Mesna

V - Various

V03 - All other therapeutic products

V03A - All other therapeutic products

V03AF - Detoxifying agents for antineoplastic treatment

V03AF01 - Mesna

API SUPPLIERS

01

Aarti Pharmalabs

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

Aarti Pharmalabs is a partner of choice for APIs & Intermediates and the largest Indian manufacturer of Xanthine Derivatives.

Contact Supplier

India

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Digital Content

USDMF

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CEP/COS

JDMF EU-WC

NDC

KDMF VMF Others AUDIT

02

Zhejiang Hisun Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

03

Solara Active Pharma Sciences

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

Not Confirmed

09

Guangzhou Tosun Pharmaceutical

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

10

Tecoland Corporation

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

AES 2024

Not Confirmed

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USDMF

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CEP/COS

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JDMF

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API Reference Price

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\/ MAHARASHTRA","supplier":"AARTI PHARMALABS","supplierCountry":"INDIA","foreign_port":"MEXICO CITY","customer":"PHARMASERVICE SA DE ","customerCountry":"MEXICO","quantity":"104.71","actualQuantity":"104.71","unit":"KGS","unitRateFc":"745","totalValueFC":"77050.4","currency":"USD","unitRateINR":55123.674911660783,"date":"30-Oct-2021","totalValueINR":"5772000","totalValueInUsd":"77050.4","indian_port":"BOMBAY AIR","hs_no":"29420090","bill_no":"5708149","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MEXICO","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"UDYOG KSHETRA,2ND FLOOR,MULUNDGOREGAON LINK ROAD,MULUND (W),, MUMBAI \/ MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1636309800,"product":"PHARMACEUTICAL RAW MATERIALS: MESNA PH.","address":"UDYOG KSHETRA,2ND FLOOR,MULUNDGOREGAON LINK ROAD,MULUND (W),","city":"MUMBAI \/ 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Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country	Total Quantity (KGS)	Average Price (USD/KGS)	Number of Transactions

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Related Excipient Companies

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Excipients by Applications

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Fillers, Diluents & Binders

Direct Compression

Thickeners and Stabilizers

Controlled & Modified Release

Co-Processed Excipients

Granulation

Solubilizers

Coating Systems & Additives

Lubricants & Glidants

Disintegrants & Superdisintegrants

Topical

Taste Masking

Film Formers & Plasticizers

Chewable & Orodispersible Aids

Parenteral

Coloring Agents

Rheology Modifiers

Emulsifying Agents

Digital Content

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DATA COMPILATION #PharmaFlow

NEWS #PharmaBuzz

Global Sales Information

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US Medicaid Prescriptions

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Finished Drug Prices

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Market Place

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APIs

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FDF DOSSIERS

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REF. STANDARDS & IMPURITIES

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EDQM

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USP

Others

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ABOUT THIS PAGE

Find Mesna manufacturers, exporters & distributors on PharmaCompass

ACCESS ALL DATA

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CHEMISTRY

Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

12 API Suppliers

8 USDMF

2 CEP/COS

1 JDMF

3 EU WC

3 NDC API

5 Listed Suppliers

$ API Reference Price

FINISHED DOSAGE FORMULATIONS

49 FDF Dossiers

14 FDA Orange Book

18 Europe

3 Canada

4 Australia

3 South Africa

7 Listed Dossiers

RELATED EXCIPIENT COMPANIES

5 SPI Pharma

2 Seqens

2 DKSH

3 Faran Shimi Pharmaceutical

1 Boai NKY Pharmaceuticals Ltd

10 Gangwal Healthcare

1 Nanjing Well Pharmaceutical

4 Actylis

3 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd

17 BASF

2 DFE Pharma

2 Finar

6 Gangwal Chemicals

1 Ideal Cures Pvt Ltd

2 Ingredion Pharma Solutions

6 Kerry

8 Microlex e.U

2 Nomisma Healthcare

1 Novo Excipients

2 Pharmatrans-Sanaq

3 Pluviaendo

2 Prachin Chemical

15 Roquette

1 Seppic

3 Shanghai Shenmei Pharmaceutical Technology Co., Ltd

8 Sigachi Industries

2 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

40 Fillers, Diluents & Binders

24 Direct Compression

16 Thickeners and Stabilizers

13 Controlled & Modified Release

13 Co-Processed Excipients

12 Granulation

11 Solubilizers

11 Coating Systems & Additives

10 Lubricants & Glidants

10 Disintegrants & Superdisintegrants

9 Topical

6 Taste Masking

5 Film Formers & Plasticizers

5 Chewable & Orodispersible Aids

5 Parenteral

2 Coloring Agents

1 Rheology Modifiers

1 Emulsifying Agents

DIGITAL CONTENT

2 DATA COMPILATION #PharmaFlow

1 NEWS #PharmaBuzz

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

10 Finished Drug Prices

MARKET PLACE

7 APIs

1 FDF Dossiers

REF. STANDARDS & IMPURITIES

3 EDQM