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1. (3-iodo-(131i)benzyl)guanidine
2. 123i Labeled 3-iodobenzylguanidine
3. 125i Labeled 3-iodobenzylguanidine
4. 3 Iodobenzylguanidine
5. 3 Iodobenzylguanidine, 123i Labeled
6. 3 Iodobenzylguanidine, 125i Labeled
7. 3-iodobenzylguanidine
8. 3-iodobenzylguanidine, 123i Labeled
9. 3-iodobenzylguanidine, 125i Labeled
10. Iobenguane (131i)
11. M Iodobenzylguanidine
12. M-iodobenzylguanidine
13. Meta Iodobenzylguanidine
14. Meta-iodobenzylguanidine
15. Mibg
1. M-iodobenzylguanidine
2. 80663-95-2
3. 3-iodobenzylguanidine
4. Metaiodobenzylguanidine
5. Mibg
6. 2-[(3-iodophenyl)methyl]guanidine
7. Iobenguane (127-i)
8. Guanidine, ((3-iodophenyl)methyl)-
9. 139755-80-9
10. Guanidine,n-[(3-iodophenyl)methyl]-
11. 1-(3-iodobenzyl)guanidine
12. 2-(3-iodobenzyl)guanidine
13. 35mrw7b4ad
14. ((3-iodophenyl)methyl)guanidine
15. Meta-iodobenzylguanidine
16. (3-iodobenzyl)guanidine
17. Ncgc00015572-04
18. Unii-35mrw7b4ad
19. Sr-01000075167
20. Prestwick-07a11
21. Starbld0001019
22. Iobenguane [mi]
23. Meta-iodobenzyl Guanidine
24. Prestwick0_000490
25. Prestwick1_000490
26. Prestwick2_000490
27. Prestwick3_000490
28. Lopac-i-9890
29. 2-m-iodo-benzyl Guanidine
30. Iobenguane [vandf]
31. Chembl818
32. Lopac0_000644
33. Bspbio_000359
34. Schembl140591
35. Spbio_002280
36. Bpbio1_000395
37. Dtxsid4048438
38. Chebi:92769
39. 1-[(3-iodophenyl)methyl]guanidine
40. Zinc1538318
41. Ccg-204731
42. Db06704
43. Sdccgsbi-0050624.p002
44. Ncgc00015572-01
45. Ncgc00015572-02
46. Ncgc00015572-03
47. Ncgc00015572-06
48. Ncgc00015572-09
49. Ncgc00162211-01
50. Da-02654
51. Q3154058
52. Sr-01000075167-1
53. Brd-k43860855-065-03-6
| Molecular Weight | 275.09 g/mol |
|---|---|
| Molecular Formula | C8H10IN3 |
| XLogP3 | 1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 2 |
| Exact Mass | 274.99194 g/mol |
| Monoisotopic Mass | 274.99194 g/mol |
| Topological Polar Surface Area | 64.4 Ų |
| Heavy Atom Count | 12 |
| Formal Charge | 0 |
| Complexity | 166 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Detection of primary and metastatic pheochromocytoma or neuroblastoma
FDA Label
AdreView is a diagnostic radiopharmaceutical which contains a small quantity of iobenguane that is not expected to produce a pharmacodynamic effect. Patients with renal insufficiency may experience increased radiation exposure and impaired imaging results.
Radiopharmaceuticals
Compounds that are used in medicine as sources of radiation for radiotherapy and for diagnostic purposes. They have numerous uses in research and industry. (Martindale, The Extra Pharmacopoeia, 30th ed, p1161) (See all compounds classified as Radiopharmaceuticals.)
Enzyme Inhibitors
Compounds or agents that combine with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. (See all compounds classified as Enzyme Inhibitors.)
Antineoplastic Agents
Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)
Absorption
Iobenguane rapidly clears from the blood and is highly retained in adrenergic tissues.
Route of Elimination
Renally excreted unchanged (70%-90%) via glomerular filtration; Fecal (<1%)
Less than 10% of the dose is metabolized into m-iodohippuric acid (MIHA). However the mechanism in which this metabolite is produced is unknown.
Physical half life = 13.2 hours
Structure of iobenguane is similar to noradrenaline so it can be taken up by adrenergic tissue in the adrenal medulla, liver, heart, and spleen. Once taken up by noradrenaline transporters in the adrenergic nerve terminals, it is stored in the presynaptic storage vesicles. The radioactive iodine component is responsible for its imaging properties.
ABOUT THIS PAGE
A Metaiodobenzylguanidine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Metaiodobenzylguanidine, including repackagers and relabelers. The FDA regulates Metaiodobenzylguanidine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Metaiodobenzylguanidine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Metaiodobenzylguanidine supplier is an individual or a company that provides Metaiodobenzylguanidine active pharmaceutical ingredient (API) or Metaiodobenzylguanidine finished formulations upon request. The Metaiodobenzylguanidine suppliers may include Metaiodobenzylguanidine API manufacturers, exporters, distributors and traders.
click here to find a list of Metaiodobenzylguanidine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Metaiodobenzylguanidine DMF (Drug Master File) is a document detailing the whole manufacturing process of Metaiodobenzylguanidine active pharmaceutical ingredient (API) in detail. Different forms of Metaiodobenzylguanidine DMFs exist exist since differing nations have different regulations, such as Metaiodobenzylguanidine USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Metaiodobenzylguanidine DMF submitted to regulatory agencies in the US is known as a USDMF. Metaiodobenzylguanidine USDMF includes data on Metaiodobenzylguanidine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Metaiodobenzylguanidine USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Metaiodobenzylguanidine suppliers with USDMF on PharmaCompass.
Metaiodobenzylguanidine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Metaiodobenzylguanidine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Metaiodobenzylguanidine GMP manufacturer or Metaiodobenzylguanidine GMP API supplier for your needs.
A Metaiodobenzylguanidine CoA (Certificate of Analysis) is a formal document that attests to Metaiodobenzylguanidine's compliance with Metaiodobenzylguanidine specifications and serves as a tool for batch-level quality control.
Metaiodobenzylguanidine CoA mostly includes findings from lab analyses of a specific batch. For each Metaiodobenzylguanidine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Metaiodobenzylguanidine may be tested according to a variety of international standards, such as European Pharmacopoeia (Metaiodobenzylguanidine EP), Metaiodobenzylguanidine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Metaiodobenzylguanidine USP).
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