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Chemistry

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Also known as: Metaraminol bitartrate, 33402-03-8, 3-[(1r,2s)-2-amino-1-hydroxypropyl]phenol;2,3-dihydroxybutanedioic acid, Metaradrine bitartrate, Prestwick_592, Prestwick0_000197
Molecular Formula
C13H19NO8
Molecular Weight
317.29  g/mol
InChI Key
VENXSELNXQXCNT-YDYUUSCQSA-N

Metaradrine Bitartrate
A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.
1 2D Structure

Metaradrine Bitartrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
3-[(1R,2S)-2-amino-1-hydroxypropyl]phenol;2,3-dihydroxybutanedioic acid
2.1.2 InChI
InChI=1S/C9H13NO2.C4H6O6/c1-6(10)9(12)7-3-2-4-8(11)5-7;5-1(3(7)8)2(6)4(9)10/h2-6,9,11-12H,10H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t6-,9-;/m0./s1
2.1.3 InChI Key
VENXSELNXQXCNT-YDYUUSCQSA-N
2.1.4 Canonical SMILES
CC(C(C1=CC(=CC=C1)O)O)N.C(C(C(=O)O)O)(C(=O)O)O
2.1.5 Isomeric SMILES
C[C@@H]([C@@H](C1=CC(=CC=C1)O)O)N.C(C(C(=O)O)O)(C(=O)O)O
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Aramine

2. Araminol

3. Bitartrate, Metaraminol

4. Hydroxyphenylpropanolamine

5. Isophenylephrine

6. M Hydroxynorephedrine

7. M Hydroxyphenylpropanolamine

8. M-hydroxynorephedrine

9. M-hydroxyphenylpropanolamine

10. Meta Hydroxynorephedrine

11. Meta-hydroxynorephedrine

12. Metaradrin

13. Metaraminol

14. Metaraminol Bitartrate

15. Metaraminol Bitartrate (1:1)

16. Metaraminol Tartrate

17. Tartrate, Metaraminol

2.2.2 Depositor-Supplied Synonyms

1. Metaraminol Bitartrate

2. 33402-03-8

3. 3-[(1r,2s)-2-amino-1-hydroxypropyl]phenol;2,3-dihydroxybutanedioic Acid

4. Metaradrine Bitartrate

5. Prestwick_592

6. Prestwick0_000197

7. Prestwick1_000197

8. Prestwick2_000197

9. Mls004712030

10. Spbio_002074

11. Schembl5564262

12. Chembl2062262

13. Amy19471

14. 3-[(1r,2s)-2-amino-1-hydroxypropyl]phenol; 2,3-dihydroxybutanedioic Acid

15. Smr003475005

16. A821761

17. Sr-01000939828

18. Sr-01000939828-2

19. 3-[(1r,2s)-2-azanyl-1-oxidanyl-propyl]phenol; 2,3-bis(oxidanyl)butanedioic Acid

2.3 Create Date
2006-04-14
3 Chemical and Physical Properties
Molecular Weight 317.29 g/mol
Molecular Formula C13H19NO8
Hydrogen Bond Donor Count7
Hydrogen Bond Acceptor Count9
Rotatable Bond Count5
Exact Mass317.11106656 g/mol
Monoisotopic Mass317.11106656 g/mol
Topological Polar Surface Area182 Ų
Heavy Atom Count22
Formal Charge0
Complexity274
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


Vasoconstrictor Agents

Drugs used to cause constriction of the blood vessels. (See all compounds classified as Vasoconstrictor Agents.)


Adrenergic alpha-1 Receptor Agonists

Compounds that bind to and activate ADRENERGIC ALPHA-1 RECEPTORS. (See all compounds classified as Adrenergic alpha-1 Receptor Agonists.)


ABOUT THIS PAGE

Looking for 33402-03-8 / Metaradrine Bitartrate API manufacturers, exporters & distributors?

Metaradrine Bitartrate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Metaradrine Bitartrate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Metaradrine Bitartrate manufacturer or Metaradrine Bitartrate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Metaradrine Bitartrate manufacturer or Metaradrine Bitartrate supplier.

PharmaCompass also assists you with knowing the Metaradrine Bitartrate API Price utilized in the formulation of products. Metaradrine Bitartrate API Price is not always fixed or binding as the Metaradrine Bitartrate Price is obtained through a variety of data sources. The Metaradrine Bitartrate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Metaradrine Bitartrate

Synonyms

Metaraminol bitartrate, 33402-03-8, 3-[(1r,2s)-2-amino-1-hydroxypropyl]phenol;2,3-dihydroxybutanedioic acid, Prestwick_592, Prestwick0_000197, Prestwick1_000197

Cas Number

33402-03-8

About Metaradrine Bitartrate

A sympathomimetic agent that acts predominantly at alpha-1 adrenergic receptors. It has been used primarily as a vasoconstrictor in the treatment of HYPOTENSION.

Metaradrine Bitartrate Manufacturers

A Metaradrine Bitartrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Metaradrine Bitartrate, including repackagers and relabelers. The FDA regulates Metaradrine Bitartrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Metaradrine Bitartrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Metaradrine Bitartrate Suppliers

A Metaradrine Bitartrate supplier is an individual or a company that provides Metaradrine Bitartrate active pharmaceutical ingredient (API) or Metaradrine Bitartrate finished formulations upon request. The Metaradrine Bitartrate suppliers may include Metaradrine Bitartrate API manufacturers, exporters, distributors and traders.

Metaradrine Bitartrate GMP

Metaradrine Bitartrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Metaradrine Bitartrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Metaradrine Bitartrate GMP manufacturer or Metaradrine Bitartrate GMP API supplier for your needs.

Metaradrine Bitartrate CoA

A Metaradrine Bitartrate CoA (Certificate of Analysis) is a formal document that attests to Metaradrine Bitartrate's compliance with Metaradrine Bitartrate specifications and serves as a tool for batch-level quality control.

Metaradrine Bitartrate CoA mostly includes findings from lab analyses of a specific batch. For each Metaradrine Bitartrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Metaradrine Bitartrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Metaradrine Bitartrate EP), Metaradrine Bitartrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Metaradrine Bitartrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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