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Chemistry

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Also known as: 51-57-0, Methamphetamine hcl, (+)-methamphetamine hydrochloride, Adipex, Dexoval, S-(+)-methamphetamine hydrochloride
Molecular Formula
C10H16ClN
Molecular Weight
185.69  g/mol
InChI Key
TWXDDNPPQUTEOV-FVGYRXGTSA-N
FDA UNII
997F43Z9CV

Methamphetamine Hydrochloride
A central nervous system stimulant and sympathomimetic with actions and uses similar to DEXTROAMPHETAMINE. The smokable form is a drug of abuse and is referred to as crank, crystal, crystal meth, ice, and speed.
1 2D Structure

Methamphetamine Hydrochloride

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-N-methyl-1-phenylpropan-2-amine;hydrochloride
2.1.2 InChI
InChI=1S/C10H15N.ClH/c1-9(11-2)8-10-6-4-3-5-7-10;/h3-7,9,11H,8H2,1-2H3;1H/t9-;/m0./s1
2.1.3 InChI Key
TWXDDNPPQUTEOV-FVGYRXGTSA-N
2.1.4 Canonical SMILES
CC(CC1=CC=CC=C1)NC.Cl
2.1.5 Isomeric SMILES
C[C@@H](CC1=CC=CC=C1)NC.Cl
2.2 Other Identifiers
2.2.1 UNII
997F43Z9CV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Deoxyephedrine

2. Desoxyephedrine

3. Desoxyn

4. Hydrochloride, Methamphetamine

5. Madrine

6. Metamfetamine

7. Methamphetamine

8. Methylamphetamine

9. N Methylamphetamine

10. N-methylamphetamine

2.3.2 Depositor-Supplied Synonyms

1. 51-57-0

2. Methamphetamine Hcl

3. (+)-methamphetamine Hydrochloride

4. Adipex

5. Dexoval

6. S-(+)-methamphetamine Hydrochloride

7. Methamphetaminium Chloride

8. Tonedron

9. D-methaphetamine Hydrochloride

10. Deofed

11. Isophen

12. Desoxyn

13. Methylisomyn

14. Soxysympamine

15. Chestox

16. Desepin

17. Desodex

18. Desoxyfed

19. Desoxyne

20. Dexstim

21. Doxyfed

22. Drinalfa

23. Efroxine

24. Eufodrinal

25. Gerovit

26. Madrine

27. Pervitin

28. Syndrox

29. Destim

30. Dextim

31. Dosoxy

32. Hyphet

33. Meth

34. Obedrin-la

35. Desoxo-5

36. Metamfetamine Hydrochloride

37. Norodin Hydrochloride

38. (+)-n,alpha-dimethylphenethylamine Hydrochloride

39. Methylamphetamine Hydrochloride

40. (+)methamphetamine Hydrochloride

41. Des-o-e

42. D-desoxyephedrine Hydrochloride

43. Dee Dex 10

44. Methedrine Hydrochloride

45. Methaphetaminium Chloride

46. Semoxydrine Hydrochloride

47. Dee -5

48. Methamphetamine Hydrochloride Cii

49. Chebi:35340

50. Metamphetamine Hydrochloride

51. Dee -10

52. 997f43z9cv

53. D-o-e

54. Desoxyephedrine Hydrochloride

55. (+)-methamphetamine Chloride

56. D-methamphetamine Hydrochloride

57. Nsc-169505

58. N-methylamphetamine Hydrochloride

59. Philopon

60. Benzeneethanamine, N,alpha-dimethyl-, Hydrochloride, (alphas)-

61. (+)-methylamphetamine Hydrochloride

62. Isophen (van)

63. L-methamphetamine Hydrochloride

64. (2s)-n-methyl-1-phenylpropan-2-amine;hydrochloride

65. Gerobit

66. (+)-2-methylamino-2-phenylpropane Hydrochloride

67. D-methylamphetamine Hydrochloride

68. Levmetamfetamine Hydrochloride

69. (+)-l-methamphetamine Hydrochloride

70. Einecs 200-106-9

71. Nsc 169505

72. Wq4872m3c8

73. L-desoxyephedrine Hydrochloride

74. Unii-997f43z9cv

75. Ai3-20155

76. D-n,alpha-dimethylphenethylamine Hydrochloride

77. (s)-(+)-methamphetamine Hydrochloride

78. D-n-methyl-beta-phenylisopropylamine Hydrochloride

79. Desoxyn (tn)

80. Einecs 212-552-1

81. L-methamphetamine Hcl

82. Phenethylamine, N,alpha-dimethyl-, Hydrochloride, (+)-

83. Benzeneethanamine, N,alpha-dimethyl-, Hydrochloride, (s)-

84. Methamphetamine Hydrochloride [usp:jan]

85. (+)-methamphetamine Hydrochloride Solution

86. Ncgc00247704-01

87. Dsstox_cid_28790

88. Dsstox_rid_83059

89. Dsstox_gsid_48864

90. L-n-methyl-beta-phenylisopropylamine Hydrochloride

91. Methylamfetamine Hydrochloride

92. Schembl42100

93. N,alpha-dimethylphenethylamine Hydrochloride, (-)-

94. Unii-wq4872m3c8

95. (2s)-n-methyl-1-phenylpropan-2-amine Hydrochloride

96. (+)-(s)-n,alpha-dimethylphenethylamine Hydrochloride

97. Methamphetamine Hydrogen Chloride

98. Chembl1200952

99. Dtxsid8048864

100. Phenethylamine, N,alpha-dimethyl-, Hydrochloride, (-)-

101. Phenethylamine, N,alpha-dimethyl-, Hydrochloride, (s)-(+)-

102. Tox21_112856

103. Cas-51-57-0

104. Methamphetamine Hydrochloride (jp17/usp)

105. Methamphetamine Hydrochloride [mi]

106. Metamfetamine Hydrochloride [mart.]

107. Methamphetamine Hydrochloride [jan]

108. Metamfetamine Hydrochloride [who-dd]

109. Methamphetamine Hydrochloride [vandf]

110. D02242

111. Methamphetamine Hydrochloride [orange Book]

112. Methamphetamine Hydrochloride Cii [usp-rs]

113. Methamphetamine Hydrochloride [usp Monograph]

114. Methyl-[(2s)-1-phenylpropan-2-yl]azanium;chloride

115. Q27116464

116. (+)-(s)-n,.alpha.-dimethylphenethylamine Hydrochloride

117. Benzeneethanamine, N,.alpha.-dimethyl-, Hydrochloride, (s)-

118. Benzeneethanamine, N,alpha-dimethyl-, Hydrochloride (1:1), (alphas)-

119. Methamphetamine Hydrochloride ((s)-(+)-methamphetamine Hydrochloride)

120. Methamphetamine Hydrochloride, United States Pharmacopeia (usp) Reference Standard

121. (+)-methamphetamine Hydrochloride Solution, Analytical Standard, For Drug Analysis, 1.0 Mg/ml In Methanol

122. Methamphetamine Hydrochloride ((s)-(+)-methamphetamine Hydrochloride) 0.1 Mg/ml In Methanol (as Free Base)

123. Methamphetamine Hydrochloride ((s)-(+)-methamphetamine Hydrochloride) 1.0 Mg/ml In Methanol (as Free Base)

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 185.69 g/mol
Molecular Formula C10H16ClN
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count1
Rotatable Bond Count3
Exact Mass185.0971272 g/mol
Monoisotopic Mass185.0971272 g/mol
Topological Polar Surface Area12 Ų
Heavy Atom Count12
Formal Charge0
Complexity95
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Drug and Medication Information
4.1 Drug Information
1 of 2  
Drug NameDESOXYN
Active IngredientMETHAMPHETAMINE HYDROCHLORIDE
CompanyRECORDATI RARE (Application Number: N005378)

2 of 2  
Drug NameMETHAMPHETAMINE HYDROCHLORIDE
Active IngredientMETHAMPHETAMINE HYDROCHLORIDE
CompanyMAYNE PHARMA INC (Application Number: A091189); WEST-WARD PHARMS INT (Application Number: A203846)

5 Pharmacology and Biochemistry
5.1 MeSH Pharmacological Classification

Dopamine Agents

Any drugs that are used for their effects on dopamine receptors, on the life cycle of dopamine, or on the survival of dopaminergic neurons. (See all compounds classified as Dopamine Agents.)


Central Nervous System Stimulants

A loosely defined group of drugs that tend to increase behavioral alertness, agitation, or excitation. They work by a variety of mechanisms, but usually not by direct excitation of neurons. The many drugs that have such actions as side effects to their main therapeutic use are not included here. (See all compounds classified as Central Nervous System Stimulants.)


Dopamine Uptake Inhibitors

Drugs that block the transport of DOPAMINE into axon terminals or into storage vesicles within terminals. Most of the ADRENERGIC UPTAKE INHIBITORS also inhibit dopamine uptake. (See all compounds classified as Dopamine Uptake Inhibitors.)


Adrenergic Agents

Drugs that act on adrenergic receptors or affect the life cycle of adrenergic transmitters. Included here are adrenergic agonists and antagonists and agents that affect the synthesis, storage, uptake, metabolism, or release of adrenergic transmitters. (See all compounds classified as Adrenergic Agents.)


Adrenergic Uptake Inhibitors

Drugs that block the transport of adrenergic transmitters into axon terminals or into storage vesicles within terminals. The tricyclic antidepressants (ANTIDEPRESSIVE AGENTS, TRICYCLIC) and amphetamines are among the therapeutically important drugs that may act via inhibition of adrenergic transport. Many of these drugs also block transport of serotonin. (See all compounds classified as Adrenergic Uptake Inhibitors.)


Sympathomimetics

Drugs that mimic the effects of stimulating postganglionic adrenergic sympathetic nerves. Included here are drugs that directly stimulate adrenergic receptors and drugs that act indirectly by provoking the release of adrenergic transmitters. (See all compounds classified as Sympathomimetics.)


5.2 FDA Pharmacological Classification
5.2.1 Pharmacological Classes
Amphetamines [CS]; Appetite Suppression [PE]; Central Nervous System Stimulant [EPC]; Central Nervous System Stimulation [PE]; Increased Sympathetic Activity [PE]; Amphetamine Anorectic [EPC]

API SUPPLIERS

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01

Veranova

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Chattem Chemicals, Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

VMX
Not Confirmed
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Chattem Chemicals, Inc

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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VMX
Not Confirmed
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National Institute on Drug Abuse

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

VMX
Not Confirmed
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National Institute on Drug Abuse

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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VMX
Not Confirmed
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04

National Institute on Drug Abuse

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

VMX
Not Confirmed
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National Institute on Drug Abuse

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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VMX
Not Confirmed
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05

Norac Pharma

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

VMX
Not Confirmed
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Norac Pharma

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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VMX
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06

Dishman Carbogen Amcis

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

VMX
Not Confirmed
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07

AXYNTIS Group

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

VMX
Not Confirmed
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08

Dishman Carbogen Amcis

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

VMX
Not Confirmed
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ABOUT THIS PAGE

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) Manufacturers

A Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base), including repackagers and relabelers. The FDA regulates Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) Suppliers

A Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) supplier is an individual or a company that provides Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) active pharmaceutical ingredient (API) or Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) finished formulations upon request. The Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) suppliers may include Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) API manufacturers, exporters, distributors and traders.

click here to find a list of Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) USDMF

A Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) DMF (Drug Master File) is a document detailing the whole manufacturing process of Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) active pharmaceutical ingredient (API) in detail. Different forms of Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) DMFs exist exist since differing nations have different regulations, such as Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) DMF submitted to regulatory agencies in the US is known as a USDMF. Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) USDMF includes data on Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base)'s chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) suppliers with USDMF on PharmaCompass.

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) suppliers with NDC on PharmaCompass.

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) GMP

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) GMP manufacturer or Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) GMP API supplier for your needs.

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) CoA

A Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) CoA (Certificate of Analysis) is a formal document that attests to Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base)'s compliance with Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) specifications and serves as a tool for batch-level quality control.

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) CoA mostly includes findings from lab analyses of a specific batch. For each Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) may be tested according to a variety of international standards, such as European Pharmacopoeia (Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) EP), Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Methamphetamine Hydrochloride ((S)-(+)-Methamphetamine Hydrochloride) 0.1 mg/ml in Methanol (as free base) USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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