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Methantheline Bromide

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ACTIVE PHARMA INGREDIENTS

2 API Suppliers, 2 Listed Suppliers

2 API Suppliers
2 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

1 FDF Dossiers, 1 FDA Orange Book

1 FDF Dossiers
1 FDA Orange Book

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

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USP

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Chemistry

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Also known as: 53-46-3, Banthine, Methanthelinium bromide, Vagantin, Dixamone bromide, Frenogastrico

Molecular Formula

C₂₁H₂₆BrNO₃

Molecular Weight

420.3 g/mol

InChI Key

PQMWYJDJHJQZDE-UHFFFAOYSA-M

FDA UNII

090519SAPF

A quaternary ammonium compound that acts as an antimuscarinic agent. It has been used in the treatment of PEPTIC ULCER, in gastrointestinal disorders associated with smooth muscle spasm, and in the management of urinary incontinence, and may also be used for the treatment of HYPERHIDROSIS.

1 2D Structure

Methantheline Bromide

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

diethyl-methyl-[2-(9H-xanthene-9-carbonyloxy)ethyl]azanium;bromide

2.1.2 InChI

InChI=1S/C21H26NO3.BrH/c1-4-22(3,5-2)14-15-24-21(23)20-16-10-6-8-12-18(16)25-19-13-9-7-11-17(19)20;/h6-13,20H,4-5,14-15H2,1-3H3;1H/q+1;/p-1

2.1.3 InChI Key

PQMWYJDJHJQZDE-UHFFFAOYSA-M

2.1.4 Canonical SMILES

CC[N+](C)(CC)CCOC(=O)C1C2=CC=CC=C2OC3=CC=CC=C13.[Br-]

2.2 Other Identifiers

2.2.1 UNII

090519SAPF

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Banthine

2. Methantheline

3. Vagantin

2.3.2 Depositor-Supplied Synonyms

1. 53-46-3

2. Banthine

3. Methanthelinium Bromide

4. Vagantin

5. Dixamone Bromide

6. Frenogastrico

7. Gastrosedan

8. Resobantin

9. Ulcudexter

10. Asabaine

11. Banthin

12. Doladene

13. Gastron

14. Metantyl

15. Metaxan

16. Methelina

17. Vagamin

18. Xanteline

19. Avagal

20. Ulcine

21. Mtb 51

22. Methantheline Bromide (200 Mg)

23. Sc 2910

24. Banthine Bromide

25. Methantheline (bromide)

26. Methanthine Bromide

27. Nsc-32145

28. Methanthelinium Bromide [inn]

29. 090519sapf

30. Diethyl(2-hydroxyethyl)methylammonium Bromide Xanthene-9-carboxylate

31. Xanthene-9-carboxylic Acid, Ester With Diethyl(2-hydroxyethyl)methylammonium Bromide

32. Diethyl-methyl-[2-(9h-xanthene-9-carbonyloxy)ethyl]azanium;bromide

33. Dsstox_cid_3277

34. Ethanaminium, N,n-diethyl-n-methyl-2-((9h-xanthen-9-ylcarbonyl)oxy)-, Bromide

35. Dsstox_rid_76953

36. Dsstox_gsid_23277

37. Methanthelinium Bromide (inn)

38. Mantheline

39. Mtb 51; Mantheline; Metantyl; Metanyl; Metaxan; Methanide

40. Metantelinio Bromuro [dcit]

41. Metantelinio Bromuro

42. Gastric Mucin

43. Methanthelinii Bromidum

44. Bromuro De Metantelinio

45. Cas-53-46-3

46. Bromure De Methanthelinum

47. Ncgc00016239-01

48. Einecs 200-176-0

49. Methanthelinii Bromidum [inn-latin]

50. Nsc 32145

51. Bromuro De Metantelinio [inn-spanish]

52. Bromure De Methanthelinum [inn-french]

53. Methantheline Bromide [usp]

54. Unii-090519sapf

55. Ulcine Bromide

56. Banthine (tn)

57. Beta-diethylaminoethyl Xanthene-9-carboxylate Methobromide

58. Mls002154138

59. Schembl250100

60. Chebi:6818

61. Chembl1200988

62. Dtxsid7023277

63. Hms1571e14

64. Hms2098e14

65. Hms2230k17

66. Hms3373j03

67. Hms3715e14

68. Methantheline Bromide [mi]

69. Methanthelinebromide(200mg)

70. Nsc32145

71. Tox21_110320

72. Methantheline Bromide [vandf]

73. Ammonium, Diethyl(2-hydroxyethyl)methyl-, Bromide, Xanthene-9-carboxylate

74. Tox21_110320_1

75. Ccg-221066

76. Methanthelinium Bromide [mart.]

77. Methanthelinium Bromide [who-dd]

78. Ncgc00016239-04

79. Ammonium, Bromide, Xanthene-9-carboxylate

80. Smr001233445

81. Methantheline Bromide [orange Book]

82. D00721

83. M-3075

84. Sr-01000841194

85. Sr-01000841194-2

86. Wln: T C666 Bo Ihj Ivo2k2&2&1 &q &e

87. Q27236434

88. .beta.-diethylaminoethyl 9-xanthenecarboxylate Methobromide

89. .beta.-diethylaminoethyl Xanthene-9-carboxylate Methobromide

90. Diethyl(2-hydroxyethyl)methylammoniumbromide Xanthene-9-carboxylate

91. Ethanaminium,n-diethyl-n-methyl-2-[(9h-xanthen-9-ylcarbonyl)oxy]-, Bromide

92. N,n-diethyl-n-methyl-2-[(9h-xanthen-9-ylcarbonyl)oxy]ethanaminium Bromide

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₁H₂₆BrNO₃
Molecular Weight	420.3 g/mol
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	419.10961 g/mol
Monoisotopic Mass	419.10961 g/mol
Topological Polar Surface Area	35.5 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	426
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Muscarinic Antagonists

Drugs that bind to but do not activate MUSCARINIC RECEPTORS, thereby blocking the actions of endogenous ACETYLCHOLINE or exogenous agonists. Muscarinic antagonists have widespread effects including actions on the iris and ciliary muscle of the eye, the heart and blood vessels, secretions of the respiratory tract, GI system, and salivary glands, GI motility, urinary bladder tone, and the central nervous system. (See all compounds classified as Muscarinic Antagonists.)

API SUPPLIERS

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ABOUT THIS PAGE

Methantheline Bromide Manufacturers

A Methantheline Bromide manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Methantheline Bromide, including repackagers and relabelers. The FDA regulates Methantheline Bromide manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Methantheline Bromide API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Methantheline Bromide manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Methantheline Bromide Suppliers

A Methantheline Bromide supplier is an individual or a company that provides Methantheline Bromide active pharmaceutical ingredient (API) or Methantheline Bromide finished formulations upon request. The Methantheline Bromide suppliers may include Methantheline Bromide API manufacturers, exporters, distributors and traders.

click here to find a list of Methantheline Bromide suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Methantheline Bromide GMP

Methantheline Bromide Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Methantheline Bromide GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Methantheline Bromide GMP manufacturer or Methantheline Bromide GMP API supplier for your needs.

Methantheline Bromide CoA

A Methantheline Bromide CoA (Certificate of Analysis) is a formal document that attests to Methantheline Bromide's compliance with Methantheline Bromide specifications and serves as a tool for batch-level quality control.

Methantheline Bromide CoA mostly includes findings from lab analyses of a specific batch. For each Methantheline Bromide CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Methantheline Bromide may be tested according to a variety of international standards, such as European Pharmacopoeia (Methantheline Bromide EP), Methantheline Bromide JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Methantheline Bromide USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.