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Chemistry

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Also known as: Melsedin, Somnofac, Mequal, Optimil, Parest, 340-56-7
Molecular Formula
C16H15ClN2O
Molecular Weight
286.75  g/mol
InChI Key
KJUHIXIWKSVBKB-UHFFFAOYSA-N
FDA UNII
RJQ4G25ZRH

Methaqualone
A quinazoline derivative with hypnotic and sedative properties. It has been withdrawn from the market in many countries because of problems with abuse. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
1 2D Structure

Methaqualone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-methyl-3-(2-methylphenyl)quinazolin-4-one;hydrochloride
2.1.2 InChI
InChI=1S/C16H14N2O.ClH/c1-11-7-3-6-10-15(11)18-12(2)17-14-9-5-4-8-13(14)16(18)19;/h3-10H,1-2H3;1H
2.1.3 InChI Key
KJUHIXIWKSVBKB-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1=CC=CC=C1N2C(=NC3=CC=CC=C3C2=O)C.Cl
2.2 Other Identifiers
2.2.1 UNII
RJQ4G25ZRH
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Hydrochloride, Methaqualone

2. Methaqualone

3. Metolquizolone

4. Optimil

5. Ortonal

6. Quaalude

2.3.2 Depositor-Supplied Synonyms

1. Melsedin

2. Somnofac

3. Mequal

4. Optimil

5. Parest

6. 340-56-7

7. Methaqualone Hcl

8. Melsed Hcl

9. Mtq Hydrochloride

10. Sopor Hydrochloride

11. Somnafac

12. Quaalude Hydrochloride

13. Hyminal Monohydrochloride

14. Tr 495 Monohydrochloride

15. Methylquinazolone Hydrochloride

16. Nsc-75892

17. Rjq4g25zrh

18. 2-methyl-3-(o-tolyl)-4-quinazolone Hydrochloride

19. 4(3h)-quinazolinone, 2-methyl-3-(2-methylphenyl)-, Monohydrochloride

20. 2-methyl-3-tolylchinazolon-4 Hydrochloride

21. 2915-01-7

22. 2-methyl-3-(2-methylphenyl)quinazolin-4-one Hydrochloride

23. Mozambin Hydrochloride

24. 2-methyl-3-(2-methylphenyl)quinazolin-4-one;hydrochloride

25. Einecs 206-431-2

26. Unii-rjq4g25zrh

27. Nsc 75892

28. Chi 38

29. Methaqualone Hydrochloride [usp]

30. Qz 2 Hydrochloride

31. 2-methyl-3-tolylchinazolon-4 Hydrochloride [german]

32. 2-methyl-3-o-tolyl-4(3h)-quinazolinone Hydrochloride

33. 2-methyl-3-o-tolyl-4(3h)-quinazolinone Monohydrochloride

34. 2-metil-3-(o-tolil)-4-chinazolone Chloridrato [italian]

35. 4(3h)-quinazolinone, 2-methyl-3-o-tolyl-, Hydrochloride

36. 2-metil-3-(o-tolil)-4-chinazolone Chloridrato

37. Schembl3500629

38. Chembl2106829

39. Dtxsid10951751

40. 4(3h)-quinazolinone, 2-methyl-3-o-tolyl-, Monohydrochloride

41. Nsc75892

42. 4(3h)-quinazolinone, Hydrochloride

43. 2-methyl-3-(2'-trifluormethylphenyl) Chinazolon-4 Hydrochloride [german]

44. 4(3h)-quinazolinone, 2-methyl-3-(o-trifluoromethylphenyl)-, Hydrochloride

45. Akos027439985

46. 4(3h)-quinazolinone, Monohydrochloride

47. Methaqualone Hydrochloride [mi]

48. Methaqualone Hydrochloride [who-dd]

49. Wln: T66 Bvn Enj Cr B1 & D1

50. Ft-0603381

51. Q27288151

52. 2-methyl-3-(2'-trifluormethylphenyl) Chinazolon-4 Hydrochloride

53. 2-methyl-3-(2-methylphenyl)quinazolin-4(3h)-one--hydrogen Chloride (1/1)

2.4 Create Date
2005-08-08
3 Chemical and Physical Properties
Molecular Weight 286.75 g/mol
Molecular Formula C16H15ClN2O
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count1
Exact Mass286.0872908 g/mol
Monoisotopic Mass286.0872908 g/mol
Topological Polar Surface Area32.7 Ų
Heavy Atom Count20
Formal Charge0
Complexity390
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Hypnotics and Sedatives

Drugs used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. (See all compounds classified as Hypnotics and Sedatives.)


ABOUT THIS PAGE

Methaqualone Manufacturers

A Methaqualone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Methaqualone, including repackagers and relabelers. The FDA regulates Methaqualone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Methaqualone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Methaqualone Suppliers

A Methaqualone supplier is an individual or a company that provides Methaqualone active pharmaceutical ingredient (API) or Methaqualone finished formulations upon request. The Methaqualone suppliers may include Methaqualone API manufacturers, exporters, distributors and traders.

click here to find a list of Methaqualone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Methaqualone USDMF

A Methaqualone DMF (Drug Master File) is a document detailing the whole manufacturing process of Methaqualone active pharmaceutical ingredient (API) in detail. Different forms of Methaqualone DMFs exist exist since differing nations have different regulations, such as Methaqualone USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Methaqualone DMF submitted to regulatory agencies in the US is known as a USDMF. Methaqualone USDMF includes data on Methaqualone's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Methaqualone USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Methaqualone suppliers with USDMF on PharmaCompass.

Methaqualone GMP

Methaqualone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Methaqualone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Methaqualone GMP manufacturer or Methaqualone GMP API supplier for your needs.

Methaqualone CoA

A Methaqualone CoA (Certificate of Analysis) is a formal document that attests to Methaqualone's compliance with Methaqualone specifications and serves as a tool for batch-level quality control.

Methaqualone CoA mostly includes findings from lab analyses of a specific batch. For each Methaqualone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Methaqualone may be tested according to a variety of international standards, such as European Pharmacopoeia (Methaqualone EP), Methaqualone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Methaqualone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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