Synopsis
Synopsis
0
API Suppliers
0
USDMF
0
CEP/COS
0
JDMF
0
EU WC
0
KDMF
0
NDC API
0
VMF
0
Listed Suppliers
0
EDQM
0
USP
0
JP
0
Others
0
Europe
0
Canada
0
Australia
0
South Africa
0
Listed Dossiers
DRUG PRODUCT COMPOSITIONS
0
US Patents
0
US Exclusivities
0
Health Canada Patents
US Medicaid
NA
Annual Reports
NA
Regulatory FDF Prices
NA
0
API
0
FDF
0
Data Compilation #PharmaFlow
0
Stock Recap #PipelineProspector
0
Weekly News Recap #Phispers
0
News #PharmaBuzz
1. Endiemal
2. Metharbitone
3. Methobarbitone
1. Metharbitone
2. Methylbarbital
3. Gemonil
4. Metabarbital
5. N-methylbarbital
6. Endiemalum
7. Metharbutal
8. 50-11-3
9. 1-methylbarbital
10. Endiemal
11. Gemonit
12. 5,5-diethyl-1-methylbarbituric Acid
13. 5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
14. Sch 412
15. An 23
16. Metharbital Ciii
17. Nsc 27156
18. 2,4,6(1h,3h,5h)-pyrimidinetrione, 5,5-diethyl-1-methyl-
19. Barbituric Acid, 5,5-diethyl-1-methyl-
20. Methabarbital
21. Nsc-27156
22. 5,5-diethyl-1-methylpyrimidine-2,4,6(1h,3h,5h)-trione
23. Methabarbitone
24. Metarbitale [dcit]
25. 02os7k758t
26. Metharbital Ciii (200 Mg)
27. Metarbital [inn-spanish]
28. Ncgc00181148-01
29. Metarbitale
30. Metharbitalum
31. Metarbital
32. Metharbitalum [inn-latin]
33. Gemonil (tn)
34. Metharbital (jan/inn)
35. Einecs 200-011-2
36. Brn 0184688
37. Unii-02os7k758t
38. 5,5-diethyl-1-methyl-2,4,6(1h,3h,5h)-pyrimidinetrione
39. Metharbital [usp:inn:ban:jan]
40. Metharbital [mi]
41. Metharbital [inn]
42. Metharbital [jan]
43. Dsstox_cid_3280
44. Chembl450
45. Metharbital [vandf]
46. Dsstox_rid_76955
47. Metharbital [mart.]
48. Dsstox_gsid_23280
49. Schembl78867
50. Metharbital [who-dd]
51. 5-24-09-00144 (beilstein Handbook Reference)
52. Gtpl7230
53. Dtxsid6023280
54. Schembl22556220
55. Chebi:31827
56. Metharbital [orange Book]
57. Metharbital 1.0 Mg/ml In Methanol
58. Nsc27156
59. Zinc5508997
60. Tox21_112752
61. Barbituric Acid,5-diethyl-1-methyl-
62. 1-methyl-5,5-diethyl Barbituric Acid
63. Akos006239548
64. Wln: T6vmvnv Fhj D1 F2 F2
65. Db00463
66. Cas-50-11-3
67. Ft-0692647
68. 5,5-diethyl-1-methyl-barbituric-acid
69. D01382
70. Q1176294
71. 5,5-diethyl-1-methyl-2,4,6-trioxo-hexahydropyrimidine
72. Z2205958937
73. 2,6(1h,3h,5h)-pyrimidinetrione, 5,5-diethyl-1-methyl-
74. 5,5-diethyl-1-methyl-2,4,6(1h,3h,5h)-pyrimidinetrione #
75. 5,5-diethyl-6-hydroxy-3-methyl-2,3,4,5-tetrahydropyrimidine-2,4-dione
76. Vok
| Molecular Weight | 198.22 g/mol |
|---|---|
| Molecular Formula | C9H14N2O3 |
| XLogP3 | 1.2 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 198.10044231 g/mol |
| Monoisotopic Mass | 198.10044231 g/mol |
| Topological Polar Surface Area | 66.5 Ų |
| Heavy Atom Count | 14 |
| Formal Charge | 0 |
| Complexity | 294 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Metharbital is used for the treatment of epilepsy.
Metharbital, a barbiturate, is used for the treatment of short term insomnia. It belongs to a group of medicines called central nervous system (CNS) depressants that induce drowsiness and relieve tension or nervousness. Little analgesia is conferred by barbiturates; their use in the presence of pain may result in excitation.
N - Nervous system
N03 - Antiepileptics
N03A - Antiepileptics
N03AA - Barbiturates and derivatives
N03AA30 - Metharbital
Metharbital binds at a distinct binding site associated with a Cl- ionopore at the GABAA receptor, increasing the duration of time for which the Cl- ionopore is open. The post-synaptic inhibitory effect of GABA in the thalamus is, therefore, prolonged. All of these effects are associated with marked decreases in GABA-sensitive neuronal calcium conductance (gCa). The net result of barbiturate action is acute potentiation of inhibitory GABAergic tone. Barbiturates also act through potent (if less well characterized) and direct inhibition of excitatory AMPA-type glutamate receptors, resulting in a profound suppression of glutamatergic neurotransmission.
ABOUT THIS PAGE
67
PharmaCompass offers a list of Metharbital API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Metharbital manufacturer or Metharbital supplier for your needs.
Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Metharbital manufacturer or Metharbital supplier.
PharmaCompass also assists you with knowing the Metharbital API Price utilized in the formulation of products. Metharbital API Price is not always fixed or binding as the Metharbital Price is obtained through a variety of data sources. The Metharbital Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.
A Metharbital manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Metharbital, including repackagers and relabelers. The FDA regulates Metharbital manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Metharbital API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Metharbital supplier is an individual or a company that provides Metharbital active pharmaceutical ingredient (API) or Metharbital finished formulations upon request. The Metharbital suppliers may include Metharbital API manufacturers, exporters, distributors and traders.
Metharbital Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Metharbital GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Metharbital GMP manufacturer or Metharbital GMP API supplier for your needs.
A Metharbital CoA (Certificate of Analysis) is a formal document that attests to Metharbital's compliance with Metharbital specifications and serves as a tool for batch-level quality control.
Metharbital CoA mostly includes findings from lab analyses of a specific batch. For each Metharbital CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Metharbital may be tested according to a variety of international standards, such as European Pharmacopoeia (Metharbital EP), Metharbital JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Metharbital USP).
