Find Methicillin manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: Sodium methicillin, Meticillin sodium, 132-92-3, Methicillin sodium salt, Dimocillin sodium, Staphcillin
Molecular Formula
C17H19N2NaO6S
Molecular Weight
402.4  g/mol
InChI Key
MGFZNWDWOKASQZ-UMLIZJHQSA-M
FDA UNII
NBQ410S76Y

Methicillin
One of the PENICILLINS which is resistant to PENICILLINASE but susceptible to a penicillin-binding protein. It is inactivated by gastric acid so administered by injection.
1 2D Structure

Methicillin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
sodium;(2S,5R,6R)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
2.1.2 InChI
InChI=1S/C17H20N2O6S.Na/c1-17(2)12(16(22)23)19-14(21)11(15(19)26-17)18-13(20)10-8(24-3)6-5-7-9(10)25-4;/h5-7,11-12,15H,1-4H3,(H,18,20)(H,22,23);/q;+1/p-1/t11-,12+,15-;/m1./s1
2.1.3 InChI Key
MGFZNWDWOKASQZ-UMLIZJHQSA-M
2.1.4 Canonical SMILES
CC1(C(N2C(S1)C(C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)[O-])C.[Na+]
2.1.5 Isomeric SMILES
CC1([C@@H](N2[C@H](S1)[C@@H](C2=O)NC(=O)C3=C(C=CC=C3OC)OC)C(=O)[O-])C.[Na+]
2.2 Other Identifiers
2.2.1 UNII
NBQ410S76Y
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Dimethoxyphenyl Penicillin

2. Methicillin

3. Methicillin Hydrate, Monosodium Salt

4. Methicillin Monohydrate, Monosodium Salt

5. Meticillin

6. Metin

7. Penicillin, Dimethoxyphenyl

8. Staphcillin

2.3.2 Depositor-Supplied Synonyms

1. Sodium Methicillin

2. Meticillin Sodium

3. 132-92-3

4. Methicillin Sodium Salt

5. Dimocillin Sodium

6. Staphcillin

7. Celbenin

8. Methicillin Sodium Anhydrous

9. Meticillin Sodium Salt

10. Methicillin (sodium Salt)

11. Nbq410s76y

12. Belfacillin

13. Synticillin

14. Penaureus

15. Staficyn

16. Chebi:52065

17. Estafcilina

18. Celpilline

19. Cinopenil

20. Flabelline

21. Lucopenin

22. Penysol

23. Dimocillin-r-2

24. Chembl1164

25. Smr000539526

26. Sodium Dimethoxyphenylpencillin

27. Sq-16123

28. Einecs 205-083-9

29. 2,6-dimethoxyphenyl Penicillin Sodium

30. Unii-nbq410s76y

31. Sq 16123

32. Sodium 6beta-(2,6-dimethoxybenzamido)penicillanate

33. Sodium (2,6-dimethoxyphenyl)penicillin

34. Sodium 6beta-(2,6-dimethoxybenzamido)-2,2-dimethylpenam-3alpha-carboxylate

35. Sodium (2s,5r,6r)-6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

36. Schembl34135

37. Mls001304185

38. Mls002695968

39. Spectrum1500395

40. Methicillin Sodium Salt, 90%

41. Methicillin Sodium [mi]

42. Hms500e22

43. Dtxsid30872398

44. Hms1920l15

45. Hms2091d10

46. Hms3715g20

47. Meticillin Sodium [who-dd]

48. Hy-b0974

49. Ccg-39483

50. Mfcd07787409

51. Akos015900096

52. Cs-4464

53. 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic Acid, 6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-, Monosodium Salt

54. Q27123143

55. 4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid,6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-,sodium Salt(1:1),(2s,5r,6r)-

56. Sodium (2s,5r,6r)-6-(2,6-dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

2.4 Create Date
2008-02-05
3 Chemical and Physical Properties
Molecular Weight 402.4 g/mol
Molecular Formula C17H19N2NaO6S
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count7
Rotatable Bond Count5
Exact Mass402.08615179 g/mol
Monoisotopic Mass402.08615179 g/mol
Topological Polar Surface Area133 Ų
Heavy Atom Count27
Formal Charge0
Complexity606
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


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ABOUT THIS PAGE

Methicillin Manufacturers

A Methicillin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Methicillin, including repackagers and relabelers. The FDA regulates Methicillin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Methicillin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Methicillin Suppliers

A Methicillin supplier is an individual or a company that provides Methicillin active pharmaceutical ingredient (API) or Methicillin finished formulations upon request. The Methicillin suppliers may include Methicillin API manufacturers, exporters, distributors and traders.

click here to find a list of Methicillin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Methicillin USDMF

A Methicillin DMF (Drug Master File) is a document detailing the whole manufacturing process of Methicillin active pharmaceutical ingredient (API) in detail. Different forms of Methicillin DMFs exist exist since differing nations have different regulations, such as Methicillin USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Methicillin DMF submitted to regulatory agencies in the US is known as a USDMF. Methicillin USDMF includes data on Methicillin's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Methicillin USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Methicillin suppliers with USDMF on PharmaCompass.

Methicillin GMP

Methicillin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Methicillin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Methicillin GMP manufacturer or Methicillin GMP API supplier for your needs.

Methicillin CoA

A Methicillin CoA (Certificate of Analysis) is a formal document that attests to Methicillin's compliance with Methicillin specifications and serves as a tool for batch-level quality control.

Methicillin CoA mostly includes findings from lab analyses of a specific batch. For each Methicillin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Methicillin may be tested according to a variety of international standards, such as European Pharmacopoeia (Methicillin EP), Methicillin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Methicillin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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