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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 1247-42-3, Betapar, Betanisona, Sch 4358, Bitanisone, Betapar(meprednisone)
Molecular Formula
C22H28O5
Molecular Weight
372.5  g/mol
InChI Key
PIDANAQULIKBQS-RNUIGHNZSA-N
FDA UNII
67U96J8P35

Meprednisone
1 2D Structure

Meprednisone

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(8S,9S,10R,13S,14S,16S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
2.1.2 InChI
InChI=1S/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-20(13,2)19(15)17(25)10-21(16,3)22(12,27)18(26)11-23/h6-7,9,12,15-16,19,23,27H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,19+,20-,21-,22-/m0/s1
2.1.3 InChI Key
PIDANAQULIKBQS-RNUIGHNZSA-N
2.1.4 Canonical SMILES
CC1CC2C3CCC4=CC(=O)C=CC4(C3C(=O)CC2(C1(C(=O)CO)O)C)C
2.1.5 Isomeric SMILES
C[C@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@H]3C(=O)C[C@@]2([C@]1(C(=O)CO)O)C)C
2.2 Other Identifiers
2.2.1 UNII
67U96J8P35
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 16-methylprednisone

2. Betapar

2.3.2 Depositor-Supplied Synonyms

1. 1247-42-3

2. Betapar

3. Betanisona

4. Sch 4358

5. Bitanisone

6. Betapar(meprednisone)

7. Nsc 527579

8. Lepicortin-beta

9. Deltisona B

10. Deltacortene Beta

11. Sch-4358

12. Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-16-methyl-, (16beta)-

13. 67u96j8p35

14. Nsc-527579

15. Dsstox_cid_3260

16. Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-16-methyl-, (16b)-

17. Dsstox_rid_76945

18. Dsstox_gsid_23260

19. (8s,9s,10r,13s,14s,16s,17r)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

20. (8s,9s,10r,13s,14s,16s,17r)-17-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-7,8,9,10,12,13,14,15,16,17-decahydro-3h-cyclopenta[a]phenanthrene-3,11(6h)-dione

21. Meprednisona

22. Meprednisonum

23. Cas-1247-42-3

24. 16beta-methylprednisone

25. 16-beta-metilprednisone

26. 16-beta-methylprednisone

27. Meprednisonum [inn-latin]

28. Meprednisona [inn-spanish]

29. Meprednisone [usan:usp:inn]

30. Unii-67u96j8p35

31. Ncgc00182851-01

32. Einecs 214-996-1

33. Betapar (meprednisone)

34. Meprednisone (usp/inn)

35. Meprednisone [mi]

36. Meprednisone [inn]

37. Meprednisone [usan]

38. Schembl9512

39. Meprednisone [mart.]

40. 1,4-pregnadien-16-beta-methyl-17,21-diol-3,11,20-trione

41. Meprednisone [usp-rs]

42. Meprednisone [who-dd]

43. Chembl1201148

44. Dtxsid8023260

45. Chebi:135573

46. Meprednisone [orange Book]

47. Meprednisone [usp Impurity]

48. 17,21-dihydroxy-16beta-methylpregna-1,4-diene-3,11,20-trione

49. Hy-b0243

50. Zinc4216862

51. Tox21_113612

52. S1689

53. Akos025149904

54. Tox21_113612_1

55. Ccg-268328

56. Db09383

57. Pregna-1,4-diene-3,11,20-trione, 17,21-dihydroxy-16-methyl-, (16.beta.)-

58. Ncgc00182851-02

59. As-72185

60. Meprednisone 100 Microg/ml In Acetonitrile

61. D06673

62. Ab01274711-01

63. Ab01274711_02

64. 247m423

65. A805287

66. Sr-01000945264

67. J-005162

68. Q6817833

69. Sr-01000945264-1

70. Z1869763209

71. 17,21-dihydroxy-16.beta.-methylpregna-1,4-diene-3,11,20-trione

72. (16beta)-17,21-dihydroxy-16-methylpregna-1,4-diene-3,11,20-trione

73. (1r,2s,3as,3bs,9ar,9bs,11as)-1-hydroxy-1-(2-hydroxyacetyl)-2,9a,11a-trimethyl-1h,2h,3h,3ah,3bh,4h,5h,7h,9ah,9bh,10h,11h,11ah-cyclopenta[a]phenanthrene-7,10-dione

74. (1s,2r,10s,11s,13s,14r,15s)-14-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione

75. (8s,9s,10r,13s,14s,16s,17r)-10,13,16-trimethyl-17-oxidanyl-17-(2-oxidanylethanoyl)-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

76. (8s,9s,10r,13s,14s,16s,17r)-17-hydroxy-17-(2-hydroxy-1-oxoethyl)-10,13,16-trimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

2.4 Create Date
2005-11-20
3 Chemical and Physical Properties
Molecular Weight 372.5 g/mol
Molecular Formula C22H28O5
XLogP31.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass372.19367399 g/mol
Monoisotopic Mass372.19367399 g/mol
Topological Polar Surface Area91.7 Ų
Heavy Atom Count27
Formal Charge0
Complexity795
Isotope Atom Count0
Defined Atom Stereocenter Count7
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 ATC Code

H - Systemic hormonal preparations, excl. sex hormones and insulins

H02 - Corticosteroids for systemic use

H02A - Corticosteroids for systemic use, plain

H02AB - Glucocorticoids

H02AB15 - Meprednisone


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ABOUT THIS PAGE

Methylprednisone Manufacturers

A Methylprednisone manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Methylprednisone, including repackagers and relabelers. The FDA regulates Methylprednisone manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Methylprednisone API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Methylprednisone manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Methylprednisone Suppliers

A Methylprednisone supplier is an individual or a company that provides Methylprednisone active pharmaceutical ingredient (API) or Methylprednisone finished formulations upon request. The Methylprednisone suppliers may include Methylprednisone API manufacturers, exporters, distributors and traders.

click here to find a list of Methylprednisone suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Methylprednisone GMP

Methylprednisone Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Methylprednisone GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Methylprednisone GMP manufacturer or Methylprednisone GMP API supplier for your needs.

Methylprednisone CoA

A Methylprednisone CoA (Certificate of Analysis) is a formal document that attests to Methylprednisone's compliance with Methylprednisone specifications and serves as a tool for batch-level quality control.

Methylprednisone CoA mostly includes findings from lab analyses of a specific batch. For each Methylprednisone CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Methylprednisone may be tested according to a variety of international standards, such as European Pharmacopoeia (Methylprednisone EP), Methylprednisone JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Methylprednisone USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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