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ACTIVE PHARMA INGREDIENTS

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JDMF

JDMFs Filed

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KDMF

KDMF

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VMF

NDC API

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Europe

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Chemistry

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Also known as: 14008-44-7, Vogalene, Exp 999, 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide, Exp-999, 4-piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]-
Molecular Formula
C22H27N3O3S2
Molecular Weight
445.6  g/mol
InChI Key
BQDBKDMTIJBJLA-UHFFFAOYSA-N
FDA UNII
238S75V9AV

Metopimazine
1 2D Structure

Metopimazine

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide
2.1.2 InChI
InChI=1S/C22H27N3O3S2/c1-30(27,28)17-7-8-21-19(15-17)25(18-5-2-3-6-20(18)29-21)12-4-11-24-13-9-16(10-14-24)22(23)26/h2-3,5-8,15-16H,4,9-14H2,1H3,(H2,23,26)
2.1.3 InChI Key
BQDBKDMTIJBJLA-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CS(=O)(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2CCCN4CCC(CC4)C(=O)N
2.2 Other Identifiers
2.2.1 UNII
238S75V9AV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1-(3-(2-methylsulfonylphenothiazin-10-yl) Propyl)isonipecotinamide

2. Metopimazine Hydrochloride

3. Vogalene

2.3.2 Depositor-Supplied Synonyms

1. 14008-44-7

2. Vogalene

3. Exp 999

4. 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide

5. Exp-999

6. 4-piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]-

7. 1-(3-(2-(methylsulfonyl)phenothiazin-10-yl)propyl)isonipecotamide

8. 238s75v9av

9. 4-piperidinecarboxamide, 1-(3-(2-(methylsulfonyl)-10h-phenothiazin-10-yl)propyl)-

10. Rp-9965

11. Nortrip

12. 1-[3-[2-(methylsulfonyl)phenothiazin-10-yl]propyl]isonipecotamide

13. 1-(3-(2-(methylsulfonyl)-10h-phenothiazin-10-yl)propyl)-4-piperidinecarboxamide

14. 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]-4-piperidinecarboxamide

15. Metopimazina

16. Metopimazinum

17. Metopimazinum [inn-latin]

18. Metopimazina [inn-spanish]

19. Rp 9965

20. Einecs 237-818-4

21. Brn 4278585

22. Unii-238s75v9av

23. Metopimazine [usan:inn:ban]

24. 1-(3-(2-(methylsulfonyl)-10h-phenothiazin-10-yl)propyl)piperidin-4-carboxamide

25. 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]piperidin-4-carboxamide

26. 2-methylsulfonyl-10-(3-(4-carbamoylpiperidino)propyl)phenothiazine

27. Metopimazine [mi]

28. 10-(3-(4-carbamoylpiperidine)propyl)-2-(methanesulfonyl)phenothiazine

29. Phenothiazine, 10-(3-(4'-carbamoylpiperidino)propyl)-2-methylsulfonyl-

30. Metopimazine (usan/inn)

31. Metopimazine [inn]

32. 1-(3-(2-(methylsulfonyl)phenothiazin-10-yl)propyl)-4-piperidinecarboxamide

33. 4-piperidinecarboxamide, 1-(3-(2-(methanesulfonyl)phenothiazin-10-yl)propyl)-

34. Metopimazine [usan]

35. Schembl49905

36. Metopimazine [mart.]

37. Metopimazine [who-dd]

38. Chembl398615

39. Bdbm82383

40. Gtpl11140

41. Dtxsid80161224

42. Chebi:135726

43. Bdbm179867

44. Zinc537996

45. Cas_26388

46. Ng-101

47. Nsc_26388

48. Akos005065914

49. Isonipecotamide, 1-(3-(2-(methylsulfonyl)phenothiazin-10-yl)propyl)-

50. Bcp9000921

51. Db13591

52. Us9132134, Metopimazine (ng101)

53. Ft-0672379

54. Ft-0672380

55. D05010

56. Q194682

57. J-007351

58. 1-(3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl)-4-piperidinecarboxamide #

2.4 Create Date
2005-03-27
3 Chemical and Physical Properties
Molecular Weight 445.6 g/mol
Molecular Formula C22H27N3O3S2
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count6
Rotatable Bond Count6
Exact Mass445.14938408 g/mol
Monoisotopic Mass445.14938408 g/mol
Topological Polar Surface Area117 Ų
Heavy Atom Count30
Formal Charge0
Complexity703
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Antiemetics

Drugs used to prevent NAUSEA or VOMITING. (See all compounds classified as Antiemetics.)


4.2 ATC Code

A - Alimentary tract and metabolism

A04 - Antiemetics and antinauseants

A04A - Antiemetics and antinauseants

A04AD - Other antiemetics

A04AD05 - Metopimazine


API SUPPLIERS

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01

M2i Group

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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  • EDQM
  • WHO-GMP

Virtual BoothM2i Group, an integrated CDMO, is your French partner for development & manufacturing in fine chemistry.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
m2i group

02

TAPI Technology & API Services

Israel

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

  • fda
  • EDQM
  • WHO-GMP

Virtual BoothTAPI, a leading global supplier of APIs, provides over 350 products and customized CDMO solutions for every stage of development.

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USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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03

RHODIA INC US 08512-7500 Cranbury

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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RHODIA INC US 08512-7500 Cranbury

U.S.A

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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04

Centaur Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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Centaur Pharmaceuticals

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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05

Aesica Pharmaceuticals Limited

United Kingdom

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Biotech Digital Meet
Not Confirmed
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Aesica Pharmaceuticals Limited

United Kingdom

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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06

Lab Service

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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Lab Service

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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07

Global Calcium

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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Global Calcium

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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08

Global Calcium

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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Global Calcium

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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09

AXYNTIS Group

France

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Not Confirmed
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API Reference Price

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[{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q2","strtotime":1623004200,"product":"METOPIMAZINE [ACTIVE PHARMACEUTICAL INGR EDIENTS]","address":"CENTAUR HOUSE, SHANTI NAGAR,VAKOLA, SANTACRUZ (E),","city":"MUMBAI ,MAHARASHTRA","supplier":"CENTAUR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"SHANGHAI","customer":"M\/S.","customerCountry":"CHINA","quantity":"30.00","actualQuantity":"30","unit":"KGS","unitRateFc":"1805","totalValueFC":"53048.7","currency":"USD","unitRateINR":130050,"date":"07-Jun-2021","totalValueINR":"3901500","totalValueInUsd":"53048.7","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"2263886","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"CENTAUR HOUSE, SHANTI NAGAR,VAKOLA, SANTACRUZ (E),, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1636050600,"product":"METOPIMAZINE [ACTIVE PHARMACEUTICAL INGR","address":"CENTAUR HOUSE, SHANTI NAGAR,VAKOLA, SANTACRUZ (E),","city":"MUMBAI ,MAHARASHTRA","supplier":"CENTAUR PHARMACEUTICALS","supplierCountry":"INDIA","foreign_port":"ALGIERS","customer":"M\/S.","customerCountry":"ALGERIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"4500","totalValueFC":"13360.9","currency":"USD","unitRateINR":331666.66666666669,"date":"05-Nov-2021","totalValueINR":"995000","totalValueInUsd":"13360.9","indian_port":"BOMBAY AIR","hs_no":"29419090","bill_no":"5820860","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"ALGERIA","selfForZScoreResived":"Pharma Grade","supplierPort":"BOMBAY AIR","supplierAddress":"CENTAUR HOUSE, SHANTI NAGAR,VAKOLA, SANTACRUZ (E),, MUMBAI ,MAHARASHTRA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1641148200,"product":"METOPIMAZINE","address":"125 & 126 SIPCOT INDUSTRIAL COMPLE X,HOSUR, KRISHNAGIRI DIST, TAMILNAD","city":"HOSUR,TAMIL NADU","supplier":"GLOBAL CALCIUM","supplierCountry":"INDIA","foreign_port":"CASABLANCA, MOHAMED","customer":"TO THE ORDER OF","customerCountry":"MOROCCO","quantity":"150.00","actualQuantity":"150","unit":"KGS","unitRateFc":"1250","totalValueFC":"211240.1","currency":"EUR","unitRateINR":104906.66666666667,"date":"03-Jan-2022","totalValueINR":"15736000","totalValueInUsd":"211240.1","indian_port":"MADRAS AIR","hs_no":"29333920","bill_no":"7212829","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MOROCCO","selfForZScoreResived":"Pharma Grade","supplierPort":"MADRAS AIR","supplierAddress":"125 & 126 SIPCOT INDUSTRIAL COMPLE X,HOSUR, KRISHNAGIRI DIST, TAMILNAD, HOSUR,TAMIL NADU","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q3","strtotime":1663266600,"product":"METOPIMAZINE","address":"125 & 126 SIPCOT INDUSTRIAL COMPLE X,HOSUR, KRISHNAGIRI DIST, TAMILNAD","city":"HOSUR,TAMIL NADU","supplier":"GLOBAL CALCIUM","supplierCountry":"INDIA","foreign_port":"CAIRO","customer":"TO THE ORDER OF","customerCountry":"EGYPT","quantity":"8.00","actualQuantity":"8","unit":"KGS","unitRateFc":"3800","totalValueFC":"29697.6","currency":"USD","unitRateINR":297500,"date":"16-Sep-2022","totalValueINR":"2380000","totalValueInUsd":"29697.6","indian_port":"BANGALORE AIR","hs_no":"29333990","bill_no":"4218544","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"125 & 126 SIPCOT INDUSTRIAL COMPLE X,HOSUR, KRISHNAGIRI DIST, TAMILNAD, HOSUR,TAMIL NADU","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1709577000,"product":"GST NO: 33AAACG2998N1Z5CIN: U02429TZ1979PTC009946(BATCH#G-17B-D-001)METOPIMAZINE","address":"NO.1,2ND FLOOR,OPP CANARA BANK,","city":"BANGALORE","supplier":"GLOBAL CALCIUM","supplierCountry":"INDIA","foreign_port":"SHANGHAI - PU DONG","customer":"TO THE ORDER OF","customerCountry":"CHINA","quantity":"20.00","actualQuantity":"20","unit":"KGS","unitRateFc":"2200","totalValueFC":"43459.4","currency":"USD","unitRateINR":180434.17849999998,"date":"05-Mar-2024","totalValueINR":"3608683.57","totalValueInUsd":"43459.4","indian_port":"Bangalore Air","hs_no":"29333990","bill_no":"8069581","productDescription":"API","marketType":"REGULATED MARKET","country":"CHINA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"NO.1,2ND FLOOR,OPP CANARA BANK,, BANGALORE","customerAddress":""}]
07-Jun-2021
05-Mar-2024
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ABOUT THIS PAGE

Looking for 14008-44-7 / Metopimazine API manufacturers, exporters & distributors?

Metopimazine manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Metopimazine API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Metopimazine manufacturer or Metopimazine supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Metopimazine manufacturer or Metopimazine supplier.

PharmaCompass also assists you with knowing the Metopimazine API Price utilized in the formulation of products. Metopimazine API Price is not always fixed or binding as the Metopimazine Price is obtained through a variety of data sources. The Metopimazine Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Metopimazine

Synonyms

14008-44-7, Vogalene, Exp 999, 1-[3-(2-methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide, Exp-999, 4-piperidinecarboxamide, 1-[3-[2-(methylsulfonyl)-10h-phenothiazin-10-yl]propyl]-

Cas Number

14008-44-7

Unique Ingredient Identifier (UNII)

238S75V9AV

Metopimazine Manufacturers

A Metopimazine manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Metopimazine, including repackagers and relabelers. The FDA regulates Metopimazine manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Metopimazine API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Metopimazine manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Metopimazine Suppliers

A Metopimazine supplier is an individual or a company that provides Metopimazine active pharmaceutical ingredient (API) or Metopimazine finished formulations upon request. The Metopimazine suppliers may include Metopimazine API manufacturers, exporters, distributors and traders.

click here to find a list of Metopimazine suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Metopimazine USDMF

A Metopimazine DMF (Drug Master File) is a document detailing the whole manufacturing process of Metopimazine active pharmaceutical ingredient (API) in detail. Different forms of Metopimazine DMFs exist exist since differing nations have different regulations, such as Metopimazine USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Metopimazine DMF submitted to regulatory agencies in the US is known as a USDMF. Metopimazine USDMF includes data on Metopimazine's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Metopimazine USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Metopimazine suppliers with USDMF on PharmaCompass.

Metopimazine WC

A Metopimazine written confirmation (Metopimazine WC) is an official document issued by a regulatory agency to a Metopimazine manufacturer, verifying that the manufacturing facility of a Metopimazine active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Metopimazine APIs or Metopimazine finished pharmaceutical products to another nation, regulatory agencies frequently require a Metopimazine WC (written confirmation) as part of the regulatory process.

click here to find a list of Metopimazine suppliers with Written Confirmation (WC) on PharmaCompass.

Metopimazine NDC

National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Metopimazine as an active pharmaceutical ingredient (API).

Finished drug products

The FDA updates the NDC directory daily. The NDC numbers for Metopimazine API and other APIs are published in this directory by the FDA.

Unfinished drugs

The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

Pharmaceutical companies that manufacture Metopimazine as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

Compounded drug products

The NDC directory also contains data on finished compounded human drug products that contain Metopimazine and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Metopimazine NDC to their finished compounded human drug products, they may choose to do so.

click here to find a list of Metopimazine suppliers with NDC on PharmaCompass.

Metopimazine GMP

Metopimazine Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Metopimazine GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Metopimazine GMP manufacturer or Metopimazine GMP API supplier for your needs.

Metopimazine CoA

A Metopimazine CoA (Certificate of Analysis) is a formal document that attests to Metopimazine's compliance with Metopimazine specifications and serves as a tool for batch-level quality control.

Metopimazine CoA mostly includes findings from lab analyses of a specific batch. For each Metopimazine CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Metopimazine may be tested according to a variety of international standards, such as European Pharmacopoeia (Metopimazine EP), Metopimazine JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Metopimazine USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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