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1. 10-chloro-2,3,7,11b-tetrahydro-3-methyl-11b-(2-chlorophenyl)oxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one
2. Cs 386
3. Cs-386
1. Melex
2. 31868-18-5
3. Cs-386
4. Chebi:31842
5. S5969b6237
6. 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one
7. 10-chloro-11b-(o-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one
8. Mexazolamum
9. Mexazolam [inn:jan]
10. Mexazolamum [inn-latin]
11. Cs 386
12. 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,7,11b-tetrahydrobenzo[f]oxazolo[3,2-d][1,4]diazepin-6(5h)-one
13. Brn 1091849
14. Sedoxil
15. Unii-s5969b6237
16. Melex (tn)
17. Mexazolam (jan/inn)
18. Mexazolam [inn]
19. Mexazolam [jan]
20. Mexazolam [mi]
21. Mexazolam [mart.]
22. Mexazolam [who-dd]
23. Dsstox_cid_31504
24. Dsstox_rid_97389
25. Dsstox_gsid_57715
26. 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
27. Schembl218453
28. Chembl1743261
29. Dtxsid9057715
30. Tox21_113740
31. Db15489
32. Ncgc00253606-01
33. Oxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl-
34. Cas-31868-18-5
35. D01316
36. Q6148446
| Molecular Weight | 363.2 g/mol |
|---|---|
| Molecular Formula | C18H16Cl2N2O2 |
| XLogP3 | 3.7 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 362.0588831 g/mol |
| Monoisotopic Mass | 362.0588831 g/mol |
| Topological Polar Surface Area | 41.6 Ų |
| Heavy Atom Count | 24 |
| Formal Charge | 0 |
| Complexity | 505 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 2 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Mexazolam is indicated for the treatment of anxiety with or without psychoneurotic conditions.
N - Nervous system
N05 - Psycholeptics
N05B - Anxiolytics
N05BA - Benzodiazepine derivatives
N05BA25 - Mexazolam
Absorption
The active metabolite chloronordiazepam has a Tmax of 1-2h.
Route of Elimination
Mexazolam is mainly eliminated in the bile and feces, with <10% eliminated as metabolites in the urine. >50% of a dose of mexazolam is eliminated as the metabolite chloroxazepam.
Mexazolam is rapidly metabolized to the active metabolites chloronordiazepam and chloroxazepam.
Mexazolam follows a 2 compartment model with a first half life of 1.4h and a second half life of 76h.
Mexazolam is a benzodiazepine that binds to benzodiazepine-type receptors, inhibiting gamma-aminobutyric acid.
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About the Company : Established in 1984, R L Fine Chem Pvt. Ltd. is one of the fastest growing API companies, with a leadership position in several APIs such as antihistamines, antidepressants and mus...
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ABOUT THIS PAGE
A Mexazolam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mexazolam, including repackagers and relabelers. The FDA regulates Mexazolam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mexazolam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Mexazolam manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Mexazolam supplier is an individual or a company that provides Mexazolam active pharmaceutical ingredient (API) or Mexazolam finished formulations upon request. The Mexazolam suppliers may include Mexazolam API manufacturers, exporters, distributors and traders.
click here to find a list of Mexazolam suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
Mexazolam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Mexazolam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mexazolam GMP manufacturer or Mexazolam GMP API supplier for your needs.
A Mexazolam CoA (Certificate of Analysis) is a formal document that attests to Mexazolam's compliance with Mexazolam specifications and serves as a tool for batch-level quality control.
Mexazolam CoA mostly includes findings from lab analyses of a specific batch. For each Mexazolam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Mexazolam may be tested according to a variety of international standards, such as European Pharmacopoeia (Mexazolam EP), Mexazolam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mexazolam USP).
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