List of API Suppliers of Mexazolam API listed on PharmaCompass.com

PharmaCompass

Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

0

USDMF

US DMFs Filed

0

CEP/COS

CEP/COS Certifications

0

JDMF

JDMFs Filed

0

EU WC

EU WC

0

KDMF

KDMF

0

NDC API

NDC API

0

VMF

NDC API

API REF. PRICE (USD/KG)

MARKET PLACE

0

API

0

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

0

FDF Dossiers

FDF Dossiers

0

FDA Orange Book

FDA (Orange Book)

0

Europe

Europe

0

Canada

Canada

0

Australia

Australia

0

South Africa

South Africa

0

Listed Dossiers

Listed Dossiers

0 DRUGS IN DEVELOPMENT

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

0

EDQM

0

USP

0

JP

0

Others

PATENTS & EXCLUSIVITIES

0

US Patents

0

US Exclusivities

0

Health Canada Patents

DIGITAL CONTENT

0

Data Compilation #PharmaFlow

0

Stock Recap #PipelineProspector

0

Weekly News Recap #Phispers

0

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

NA

Annual Reports

NA

Finished Drug Prices

NA

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown
read-moreClick the button for full data set
Also known as: Melex, 31868-18-5, Cs-386, Chebi:31842, S5969b6237, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one
Molecular Formula
C18H16Cl2N2O2
Molecular Weight
363.2  g/mol
InChI Key
ANUCDXCTICZJRH-UHFFFAOYSA-N
FDA UNII
S5969B6237

Mexazolam
Mexazolam (CS-386) is a benzodiazepine indicated for the treatment of anxiety with or without psychoneurotic conditions. Mexazolam's structure is similar to that of other benzodiazepines such as [oxazolam] and [cloxazolam]. The use of benzodiazepines in the treatment of anxiety is generally a second line measure.
1 2D Structure

Mexazolam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one
2.1.2 InChI
InChI=1S/C18H16Cl2N2O2/c1-11-10-24-18(13-4-2-3-5-15(13)20)14-8-12(19)6-7-16(14)21-17(23)9-22(11)18/h2-8,11H,9-10H2,1H3,(H,21,23)
2.1.3 InChI Key
ANUCDXCTICZJRH-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CC1COC2(N1CC(=O)NC3=C2C=C(C=C3)Cl)C4=CC=CC=C4Cl
2.2 Other Identifiers
2.2.1 UNII
S5969B6237
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 10-chloro-2,3,7,11b-tetrahydro-3-methyl-11b-(2-chlorophenyl)oxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one

2. Cs 386

3. Cs-386

2.3.2 Depositor-Supplied Synonyms

1. Melex

2. 31868-18-5

3. Cs-386

4. Chebi:31842

5. S5969b6237

6. 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one

7. 10-chloro-11b-(o-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyloxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one

8. Mexazolamum

9. Mexazolam [inn:jan]

10. Mexazolamum [inn-latin]

11. Cs 386

12. 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,7,11b-tetrahydrobenzo[f]oxazolo[3,2-d][1,4]diazepin-6(5h)-one

13. Brn 1091849

14. Sedoxil

15. Unii-s5969b6237

16. Melex (tn)

17. Mexazolam (jan/inn)

18. Mexazolam [inn]

19. Mexazolam [jan]

20. Mexazolam [mi]

21. Mexazolam [mart.]

22. Mexazolam [who-dd]

23. Dsstox_cid_31504

24. Dsstox_rid_97389

25. Dsstox_gsid_57715

26. 10-chloro-11b-(2-chlorophenyl)-3-methyl-2,3,5,7-tetrahydro-[1,3]oxazolo[3,2-d][1,4]benzodiazepin-6-one

27. Schembl218453

28. Chembl1743261

29. Dtxsid9057715

30. Tox21_113740

31. Db15489

32. Ncgc00253606-01

33. Oxazolo(3,2-d)(1,4)benzodiazepin-6(5h)-one, 10-chloro-11b-(2-chlorophenyl)-2,3,7,11b-tetrahydro-3-methyl-

34. Cas-31868-18-5

35. D01316

36. Q6148446

2.4 Create Date
2005-03-25
3 Chemical and Physical Properties
Molecular Weight 363.2 g/mol
Molecular Formula C18H16Cl2N2O2
XLogP33.7
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count3
Rotatable Bond Count1
Exact Mass362.0588831 g/mol
Monoisotopic Mass362.0588831 g/mol
Topological Polar Surface Area41.6 Ų
Heavy Atom Count24
Formal Charge0
Complexity505
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Drug Indication

Mexazolam is indicated for the treatment of anxiety with or without psychoneurotic conditions.


5 Pharmacology and Biochemistry
5.1 ATC Code

N - Nervous system

N05 - Psycholeptics

N05B - Anxiolytics

N05BA - Benzodiazepine derivatives

N05BA25 - Mexazolam


5.2 Absorption, Distribution and Excretion

Absorption

The active metabolite chloronordiazepam has a Tmax of 1-2h.


Route of Elimination

Mexazolam is mainly eliminated in the bile and feces, with <10% eliminated as metabolites in the urine. >50% of a dose of mexazolam is eliminated as the metabolite chloroxazepam.


5.3 Metabolism/Metabolites

Mexazolam is rapidly metabolized to the active metabolites chloronordiazepam and chloroxazepam.


5.4 Biological Half-Life

Mexazolam follows a 2 compartment model with a first half life of 1.4h and a second half life of 76h.


5.5 Mechanism of Action

Mexazolam is a benzodiazepine that binds to benzodiazepine-type receptors, inhibiting gamma-aminobutyric acid.


API Reference Price

read-more
read-more
[{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1634495400,"product":"PHARMACEUTICAL BULK DRUG MEXAZOLAM BATCH","address":"RAY HOUSE, HIG NO. 2000, YELAHANKA NEW TOWN, YELAHANKA, MOTHER DIARY","city":"ROAD, YELAHANKA NEW TOWN, BANGALORE","supplier":"R L FINE CHEM","supplierCountry":"INDIA","foreign_port":"SANTO DOMINGO","customer":"LABORATORIOS FELTREX S.A","customerCountry":"DOMINICAN REPUBLIC","quantity":"0.25","actualQuantity":"0.25","unit":"KGS","unitRateFc":"30000","totalValueFC":"7088.3","currency":"USD","unitRateINR":2124000,"date":"18-Oct-2021","totalValueINR":"531000","totalValueInUsd":"7088.3","indian_port":"BANGALORE AIR","hs_no":"29420090","bill_no":"5367480","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"DOMINICAN REPULIC","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"RAY HOUSE, HIG NO. 2000, YELAHANKA NEW TOWN, YELAHANKA, MOTHER DIARY, ROAD, YELAHANKA NEW TOWN, BANGALORE","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1683052200,"product":"PHARMACEUTICAL BULK DRUG MEXAZOLAM IH","address":"NO.C-10, 1ST CROSS,,KSSIDC INDUSTR IAL AREA, YELAHANKA","city":"BENGALURU,KARNATAKA","supplier":"R L FINE CHEM PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"SAN SALVADOR","customer":"TO THE ORDER","customerCountry":"EL SALVADOR","quantity":"0.50","actualQuantity":"0.5","unit":"KGS","unitRateFc":"25000","totalValueFC":"12213.8","currency":"USD","unitRateINR":2010000,"date":"03-May-2023","totalValueINR":"1005000","totalValueInUsd":"12213.8","indian_port":"BANGALORE AIR","hs_no":"29420090","bill_no":"0","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EL SALVADOR","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"NO.C-10, 1ST CROSS,,KSSIDC INDUSTR IAL AREA, YELAHANKA, BENGALURU,KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1684693800,"product":"PHARMACEUTICAL BULK DRUG MEXAZOLAM IH","address":"NO.C-10, 1ST CROSS,,KSSIDC INDUSTR IAL AREA, YELAHANKA","city":"BENGALURU,KARNATAKA","supplier":"R L FINE CHEM PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"SANTO DOMINGO","customer":"TO THE ORDER","customerCountry":"DOMINICAN REPUBLIC","quantity":"0.00","actualQuantity":"0.5","unit":"GMS","unitRateFc":"6500","totalValueFC":"3062.6","currency":"USD","unitRateINR":504000,"date":"22-May-2023","totalValueINR":"252000","totalValueInUsd":"3062.6","indian_port":"BANGALORE AIR","hs_no":"29420090","bill_no":"0","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"DOMINICAN REPUBLIC","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"NO.C-10, 1ST CROSS,,KSSIDC INDUSTR IAL AREA, YELAHANKA, BENGALURU,KARNATAKA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1708626600,"product":"PHARMACEUTICAL BULK DRUG, MEXAZOLAM \/ IHBATCH NO: PDL\/MXZ\/24\/005","address":"RAY HOUSE, HIG 2000,,MOTHER DIARY","city":"BANGALORE,KARNATAKA","supplier":"R L FINE CHEM","supplierCountry":"INDIA","foreign_port":"GUATEMALA CITY","customer":"LABORATORIOS QUIMICO FARMACEUTICOS","customerCountry":"GUATEMALA","quantity":"0.10","actualQuantity":"0.1","unit":"KGS","unitRateFc":"40000","totalValueFC":"3768.6","currency":"USD","unitRateINR":3126980,"date":"23-Feb-2024","totalValueINR":"312698","totalValueInUsd":"3768.6","indian_port":"Bangalore Air","hs_no":"29420090","bill_no":"7781268","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"GAUTEMALA","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"RAY HOUSE, HIG 2000,,MOTHER DIARY, BANGALORE,KARNATAKA","customerAddress":""}]
18-Oct-2021
23-Feb-2024
KGS
overview
Loading...

Average Price (USD/KGS)

Number of Transactions

Total Quantity (KGS)

Total Value (USD)

Quantity (KGS) & Unit rate (USD/KGS) over time

API Imports and Exports

Importing Country Total Quantity
(KGS)
Average Price
(USD/KGS)
Number of Transactions

Upgrade, download data, analyse, strategize, subscribe with us contact

ABOUT THIS PAGE

Mexazolam Manufacturers | Traders | Suppliers

Mexazolam Manufacturers, Traders, Suppliers 1
75

We have 1 companies offering Mexazolam

Get in contact with the supplier of your choice:

  1. R L Fine Chem
Ask Us for Pharmaceutical Supplier and Partner
Ask Us, Find A Supplier / Partner
No Commissions, No Strings Attached, Get Connected for FREE

What are you looking for?

How can we help you?

The request can't be empty

Please read our Privacy Policy carefully

You must agree to the privacy policy

The name can't be empty
The company can't be empty.
The email can't be empty Please enter a valid email.
The mobile can't be empty