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1. Fk 463
2. Fk-463
3. Fk463
4. Micafungin
5. Mycamine
1. 208538-73-2
2. Funguard
3. Mycamine
4. Fk463 Sodium
5. Fk-463
6. Micafungin Na
7. Micafungin Sodium Salt
8. Fk 463
9. Micafungin Sodium [usan]
10. Is1up79r56
11. Chebi:80105
12. Fk463
13. Sodium;[5-[(1s,2s)-2-[(3s,6s,9s,11r,15s,18s,20r,21r,24s,25s,26s)-3-[(1r)-3-amino-1-hydroxy-3-oxopropyl]-11,20,21,25-tetrahydroxy-15-[(1r)-1-hydroxyethyl]-26-methyl-2,5,8,14,17,23-hexaoxo-18-[[4-[5-(4-pentoxyphenyl)-1,2-oxazol-3-yl]benzoyl]amino]-1,4,7,13,16,22-hexazatricyclo[22.3.0.09,13]heptacosan-6-yl]-1,2-dihydroxyethyl]-2-hydroxyphenyl] Sulfate
14. Mycamine Sodium
15. Funguard (tn)
16. Mycamine (tn)
17. Mcfg
18. Micafungin Sodium- Bio-x
19. Unii-is1up79r56
20. Micafungin Na [vandf]
21. Micafungin Sodium (jan/usan)
22. Micafungin Sodium [jan]
23. Chembl1237070
24. Ex-a4114a
25. Micafungin Sodium [mart.]
26. Micafungin Sodium [who-dd]
27. Micafungin Sodium Salt [mi]
28. Mfcd08067752
29. S4287
30. Ccg-270668
31. Micafungin Sodium [orange Book]
32. Ac-30600
33. Bm164667
34. D02465
35. Q27149252
36. Pneumocandin A0, 1-((4r,5r)-4,5-dihydroxy-n2-(4-(5-(5-(pentyloxy)phenyl)-3-isoxazolyl)benzoyl)-l-ornithine)-4-((4s)-4-hydroxy-4-(4-hydroxy-3-(sulfooxy)phenyl)-l-threonine)-, Monosodium Salt
37. Pneumocandin A0, 1-(4r,5r)-4,5-ihydroxy-2-4-5-4-(pentyloxy)henyl]-3-soxazolyl]enzoyl]--rnithine]-4-(4s)-4-ydroxy-4-4-ydroxy-3-(sulfooxy)henyl]
Molecular Weight | 1292.3 g/mol |
---|---|
Molecular Formula | C56H70N9NaO23S |
Hydrogen Bond Donor Count | 15 |
Hydrogen Bond Acceptor Count | 24 |
Rotatable Bond Count | 18 |
Exact Mass | 1291.42029497 g/mol |
Monoisotopic Mass | 1291.42029497 g/mol |
Topological Polar Surface Area | 521 Ų |
Heavy Atom Count | 90 |
Formal Charge | 0 |
Complexity | 2580 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 15 |
Undefined Atom Stereocenter Count | 0 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 2 |
1 of 2 | |
---|---|
Drug Name | Mycamine |
PubMed Health | Micafungin (Injection) |
Drug Classes | Antifungal |
Drug Label | Mycamine is a sterile, lyophilized product for intravenous (IV) infusion that contains micafungin sodium. Micafungin sodium is a semisynthetic lipopeptide (echinocandin) synthesized by a chemical modification of a fermentation product of Coleophoma e... |
Active Ingredient | Micafungin sodium |
Dosage Form | Injectable |
Route | injection; Iv (infusion) |
Strength | 100mg/vial; 50mg; 50mg/vial |
Market Status | Prescription |
Company | Astellas; Fujisawa Hlthcare |
2 of 2 | |
---|---|
Drug Name | Mycamine |
PubMed Health | Micafungin (Injection) |
Drug Classes | Antifungal |
Drug Label | Mycamine is a sterile, lyophilized product for intravenous (IV) infusion that contains micafungin sodium. Micafungin sodium is a semisynthetic lipopeptide (echinocandin) synthesized by a chemical modification of a fermentation product of Coleophoma e... |
Active Ingredient | Micafungin sodium |
Dosage Form | Injectable |
Route | injection; Iv (infusion) |
Strength | 100mg/vial; 50mg; 50mg/vial |
Market Status | Prescription |
Company | Astellas; Fujisawa Hlthcare |
Mycamine is indicated for:
* Adults, adolescents 16 years of age and elderly:
- treatment of invasive candidiasis;
- treatment of oesophageal candidiasis in patients for whom intravenous therapy is appropriate;
- prophylaxis of Candida infection in patients undergoing allogeneic haematopoietic stem-cell transplantation or patients who are expected to have neutropenia (absolute neutrophil count < 500 cells/l) for 10 or more days.
* Children (including neonates) and adolescents < 16 years of age:
- treatment of invasive candidiasis.
- prophylaxis of Candida infection in patients undergoing allogeneic haematopoietic stem-cell transplantation or patients who are expected to have neutropenia (absolute neutrophil count < 500 cells/l) for 10 or more days.
The decision to use Mycamine should take into account a potential risk for the development of liver tumours. Mycamine should therefore only be used if other antifungals are not appropriate.
Antifungal Agents
Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues. (See all compounds classified as Antifungal Agents.)
J02AX05
API Imports and Exports
Importing Country | Total Quantity (KGS) |
Average Price (USD/KGS) |
Number of Transactions |
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DRUG PRODUCT COMPOSITIONS
15 Feb 2024
// PRESS RELEASE
https://www.towayakuhin.co.jp/english/assets/info/pdf/release240215.pdf
28 Aug 2023
// GLOBENEWSWIRE
https://www.globenewswire.com/news-release/2023/08/28/2732288/0/en/Sandoz-completes-acquisition-of-leading-antifungal-agent-Mycamine-from-Astellas-reinforcing-leading-global-anti-infectives-portfolio.html
22 Feb 2023
// FDA
https://www.pharmacompass.com/pdf/news/enforcement-report-week-of-february-22-2023-51785.pdf
25 Jan 2023
// Paul Schloesser ENDPTS
https://endpts.com/sandoz-signs-deal-for-antifungal-from-astellas-in-buff-up-of-anti-infectives-portfolio/
25 Oct 2022
// ECONOMIC TIMES
https://economictimes.indiatimes.com/industry/healthcare/biotech/pharmaceuticals/usfda-approves-zydus-lifesciences-to-market-generic-micafungin-injection/articleshow/95095248.cms
24 Oct 2022
// FDA
https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=215241
Global Sales Information
Company :
Micafungin Sodium
Drug Cost (USD) : 8,180,528
Year : 2022
Prescribers : 2624
Prescriptions : 9945
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 616,055
Year : 2022
Prescribers : 185
Prescriptions : 500
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 7,233,950
Year : 2021
Prescribers : 2154
Prescriptions : 7901
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 1,693,185
Year : 2021
Prescribers : 535
Prescriptions : 1722
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 6,512,200
Year : 2020
Prescribers : 1550
Prescriptions : 5509
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 2,551,847
Year : 2020
Prescribers : 802
Prescriptions : 2521
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 8,724,569
Year : 2019
Prescribers : 1833
Prescriptions : 7309
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 7,839,431
Year : 2018
Prescribers : 1723
Prescriptions : 6639
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 6,671,486
Year : 2017
Prescribers : 1503
Prescriptions : 5606
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Company :
Micafungin Sodium
Drug Cost (USD) : 5,489,000
Year : 2016
Prescribers : 1296
Prescriptions : 4702
Portfolio PDF
Product Web Link
Virtual Booth
Digital Content
Website
Corporate PDF
Dosage Form : Dry Sub
Dosage Strength : 100mg
Price Per Pack (Euro) : 424.35
Published in :
Country : Switzerland
RX/OTC/DISCN : Class A
Dosage Form : Dry Sub
Dosage Strength : 50mg
Price Per Pack (Euro) : 253.58
Published in :
Country : Switzerland
RX/OTC/DISCN : Class A
Dosage Form : Micafungin 100Mg 10Ml 1 Units Pa...
Dosage Strength : 1 vial EV 100 mg 10 ml
Price Per Pack (Euro) : 603.25
Published in :
Country : Italy
RX/OTC/DISCN : Class H
Dosage Form : Micafungin 50Mg 10Ml 1 Units Par...
Dosage Strength : 1 vial EV 50 mg 10 ml
Price Per Pack (Euro) : 301.63
Published in :
Country : Italy
RX/OTC/DISCN : Class H
Dosage Form : Powder for infusion fluid, resol...
Dosage Strength : 100 mg
Price Per Pack (Euro) : 560.33
Published in :
Country : Norway
RX/OTC/DISCN :
Dosage Form : Powder for infusion fluid, resol...
Dosage Strength : 50 mg
Price Per Pack (Euro) : 352.73
Published in :
Country : Norway
RX/OTC/DISCN :
Main Therapeutic Indication : Infectious Diseases
Currency : USD
2020 Revenue in Millions : 257
2019 Revenue in Millions : 322
Growth (%) : -20
Main Therapeutic Indication : Infectious Diseases
Currency : USD
2021 Revenue in Millions : 15
2020 Revenue in Millions : 255
Growth (%) : -94
Main Therapeutic Indication : Infectious Diseases
Currency : USD
2022 Revenue in Millions : 107
2021 Revenue in Millions : 116
Growth (%) : -8
Main Therapeutic Indication : Infectious Diseases
Currency : USD
2022 Revenue in Millions : 9
2021 Revenue in Millions : 14
Growth (%) : -32
Main Therapeutic Indication : Anti-Fungal
Currency : USD
2018 Revenue in Millions : 325
2017 Revenue in Millions : 307
Growth (%) : 6%
Main Therapeutic Indication : Anti-fungal
Currency : USD
2016 Revenue in Millions : 363
2015 Revenue in Millions : 369
Growth (%) : -2
Main Therapeutic Indication : Infectious Diseases
Currency : USD
2019 Revenue in Millions : 326
2018 Revenue in Millions : 336
Growth (%) : -3
Main Therapeutic Indication : Anti-fungal
Currency : USD
2017 Revenue in Millions : 327
2016 Revenue in Millions : 387
Growth (%) : -15
Market Place
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Patents & EXCLUSIVITIES
ABOUT THIS PAGE
A Micafungin Sodium manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Micafungin Sodium, including repackagers and relabelers. The FDA regulates Micafungin Sodium manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Micafungin Sodium API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
click here to find a list of Micafungin Sodium manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.
A Micafungin Sodium supplier is an individual or a company that provides Micafungin Sodium active pharmaceutical ingredient (API) or Micafungin Sodium finished formulations upon request. The Micafungin Sodium suppliers may include Micafungin Sodium API manufacturers, exporters, distributors and traders.
click here to find a list of Micafungin Sodium suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.
A Micafungin Sodium DMF (Drug Master File) is a document detailing the whole manufacturing process of Micafungin Sodium active pharmaceutical ingredient (API) in detail. Different forms of Micafungin Sodium DMFs exist exist since differing nations have different regulations, such as Micafungin Sodium USDMF, ASMF (EDMF), JDMF, CDMF, etc.
A Micafungin Sodium DMF submitted to regulatory agencies in the US is known as a USDMF. Micafungin Sodium USDMF includes data on Micafungin Sodium's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Micafungin Sodium USDMF is kept confidential to protect the manufacturer’s intellectual property.
click here to find a list of Micafungin Sodium suppliers with USDMF on PharmaCompass.
The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.
The Micafungin Sodium Drug Master File in Japan (Micafungin Sodium JDMF) empowers Micafungin Sodium API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).
PMDA reviews the Micafungin Sodium JDMF during the approval evaluation for pharmaceutical products. At the time of Micafungin Sodium JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.
click here to find a list of Micafungin Sodium suppliers with JDMF on PharmaCompass.
In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.
Pharmaceutical companies submit a Micafungin Sodium Drug Master File in Korea (Micafungin Sodium KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Micafungin Sodium. The MFDS reviews the Micafungin Sodium KDMF as part of the drug registration process and uses the information provided in the Micafungin Sodium KDMF to evaluate the safety and efficacy of the drug.
After submitting a Micafungin Sodium KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Micafungin Sodium API can apply through the Korea Drug Master File (KDMF).
click here to find a list of Micafungin Sodium suppliers with KDMF on PharmaCompass.
A Micafungin Sodium written confirmation (Micafungin Sodium WC) is an official document issued by a regulatory agency to a Micafungin Sodium manufacturer, verifying that the manufacturing facility of a Micafungin Sodium active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Micafungin Sodium APIs or Micafungin Sodium finished pharmaceutical products to another nation, regulatory agencies frequently require a Micafungin Sodium WC (written confirmation) as part of the regulatory process.
click here to find a list of Micafungin Sodium suppliers with Written Confirmation (WC) on PharmaCompass.
National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Micafungin Sodium as an active pharmaceutical ingredient (API).
The FDA updates the NDC directory daily. The NDC numbers for Micafungin Sodium API and other APIs are published in this directory by the FDA.
The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.
Pharmaceutical companies that manufacture Micafungin Sodium as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.
The NDC directory also contains data on finished compounded human drug products that contain Micafungin Sodium and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Micafungin Sodium NDC to their finished compounded human drug products, they may choose to do so.
click here to find a list of Micafungin Sodium suppliers with NDC on PharmaCompass.
Micafungin Sodium Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Micafungin Sodium GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Micafungin Sodium GMP manufacturer or Micafungin Sodium GMP API supplier for your needs.
A Micafungin Sodium CoA (Certificate of Analysis) is a formal document that attests to Micafungin Sodium's compliance with Micafungin Sodium specifications and serves as a tool for batch-level quality control.
Micafungin Sodium CoA mostly includes findings from lab analyses of a specific batch. For each Micafungin Sodium CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Micafungin Sodium may be tested according to a variety of international standards, such as European Pharmacopoeia (Micafungin Sodium EP), Micafungin Sodium JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Micafungin Sodium USP).
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