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Synopsis

Synopsis

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Chemistry

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Also known as: Gentamicin c2b, 52093-21-7, Sagamicin, Santemycin, Micronomicin [inn], Xk-62-2
Molecular Formula
C20H41N5O7
Molecular Weight
463.6  g/mol
InChI Key
DNYGXMICFMACRA-XHEDQWPISA-N
FDA UNII
S9AZ0R40QV

Micronomicin
Micronomicin is an aminoglycoside antibiotic isolated from Micromonospora sagamiensis var. nonreducans. Micronomicin is an analog of gentamicin and has broad-spectrum activity against both gram-positive and gram-negative bacteria.
1 2D Structure

Micronomicin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(methylaminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
2.1.2 InChI
InChI=1S/C20H41N5O7/c1-20(28)8-29-19(14(27)17(20)25-3)32-16-12(23)6-11(22)15(13(16)26)31-18-10(21)5-4-9(30-18)7-24-2/h9-19,24-28H,4-8,21-23H2,1-3H3/t9-,10+,11-,12+,13-,14+,15+,16-,17+,18+,19+,20-/m0/s1
2.1.3 InChI Key
DNYGXMICFMACRA-XHEDQWPISA-N
2.1.4 Canonical SMILES
CC1(COC(C(C1NC)O)OC2C(CC(C(C2O)OC3C(CCC(O3)CNC)N)N)N)O
2.1.5 Isomeric SMILES
C[C@@]1(CO[C@@H]([C@@H]([C@H]1NC)O)O[C@H]2[C@@H](C[C@@H]([C@H]([C@@H]2O)O[C@@H]3[C@@H](CC[C@H](O3)CNC)N)N)N)O
2.2 Other Identifiers
2.2.1 UNII
S9AZ0R40QV
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 6'-n-methylgentamicin C

2. De 020

3. De-020

4. Gentamicin C2b

5. Kw 1062

6. Kw-1062

7. Sagamicin

8. Xk-62-2

2.3.2 Depositor-Supplied Synonyms

1. Gentamicin C2b

2. 52093-21-7

3. Sagamicin

4. Santemycin

5. Micronomicin [inn]

6. Xk-62-2

7. 6'-n-methylgentamicin C1a

8. S9az0r40qv

9. Chebi:81283

10. Kw-1062

11. (2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(methylaminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol

12. D-streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-d-erythro-hexopyranosyl-(1-4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-beta-l-arabinopyranosyl-(1-6))-2-deoxy

13. Micromicin

14. Micromycin

15. Micronomicina

16. Micronomicine

17. Micronomicinum

18. Sagamicin (obs.)

19. Gentamicin C(sub 2b)

20. Antibiotic Kw 1062

21. Antibiotic Xk 62-2

22. Ncgc00183277-01

23. Unii-s9az0r40qv

24. Micronomicine [inn-french]

25. Micronomicinum [inn-latin]

26. Micronomicina [inn-spanish]

27. 6'-n-methylgentamicin C(sub 1a)

28. De 020

29. Micronomicin (dcf)

30. Kw 1062

31. Xk 62-2

32. Micronomicin [mi]

33. Micronomicin [who-dd]

34. Schembl147893

35. Chembl373081

36. Gtpl12162

37. Dtxsid401023736

38. Hy-b1915

39. Zinc8214612

40. Akos016010141

41. Db13274

42. Cs-0013973

43. C17706

44. D08219

45. Q6839784

46. D-streptamine, O-2-amino-6-(methylamino)-2,3,4,6-tetradeoxy-alpha-d-erythro-hexopyranosyl-(1-4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-beta-l-arabinopyranosyl-(1-6))-2-deoxy-

47. O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-.alpha.-d-erythro-hexopyranosyl-(1->4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-.beta.-l-arabinopyranosyl-(1->6)-2-deoxy-d-streptamine

48. O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-a-d-erythro-hexopyranosyl-(1->4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-.beta.-l-arabinopyranosyl-(1->6))-2-deoxy-d-streptamine

49. O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-a-d-erythro-hexopyranosyl-(1-4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-beta-l-arabinopyranosyl-(1-6))-2-deoxy-d-streptamine

2.4 Create Date
2005-08-09
3 Chemical and Physical Properties
Molecular Weight 463.6 g/mol
Molecular Formula C20H41N5O7
XLogP3-4.5
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count12
Rotatable Bond Count7
Exact Mass463.30059866 g/mol
Monoisotopic Mass463.30059866 g/mol
Topological Polar Surface Area200 Ų
Heavy Atom Count32
Formal Charge0
Complexity607
Isotope Atom Count0
Defined Atom Stereocenter Count12
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


4.2 ATC Code

S - Sensory organs

S01 - Ophthalmologicals

S01A - Antiinfectives

S01AA - Antibiotics

S01AA22 - Micronomicin


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ABOUT THIS PAGE

Micronomicin Manufacturers

A Micronomicin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Micronomicin, including repackagers and relabelers. The FDA regulates Micronomicin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Micronomicin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Micronomicin Suppliers

A Micronomicin supplier is an individual or a company that provides Micronomicin active pharmaceutical ingredient (API) or Micronomicin finished formulations upon request. The Micronomicin suppliers may include Micronomicin API manufacturers, exporters, distributors and traders.

Micronomicin GMP

Micronomicin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Micronomicin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Micronomicin GMP manufacturer or Micronomicin GMP API supplier for your needs.

Micronomicin CoA

A Micronomicin CoA (Certificate of Analysis) is a formal document that attests to Micronomicin's compliance with Micronomicin specifications and serves as a tool for batch-level quality control.

Micronomicin CoA mostly includes findings from lab analyses of a specific batch. For each Micronomicin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Micronomicin may be tested according to a variety of international standards, such as European Pharmacopoeia (Micronomicin EP), Micronomicin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Micronomicin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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