Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. (See all compounds classified as Antidepressive Agents.)

Drugs that selectively block or suppress the plasma membrane transport of SEROTONIN and NORADRENALINE into axon terminals and are used as ANTIDEPRESSIVE AGENTS. (See all compounds classified as Serotonin and Noradrenaline Reuptake Inhibitors.)

Molecular Formula	C₁₅H₂₃ClN₂O
Molecular Weight	282.81 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	5
Exact Mass	282.1498911 g/mol
Monoisotopic Mass	282.1498911 g/mol
Topological Polar Surface Area	46.3 Å²
Heavy Atom Count	19
Formal Charge	0
Complexity	295
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

1 of 2
Drug Name	Fetzima
PubMed Health	Levomilnacipran (By mouth)
Drug Classes	Antidepressant
Active Ingredient	Levomilnacipran hydrochloride
Dosage Form	Capsule, extended release
Route	Oral
Strength	eq 40mg base; eq 80mg base; eq 120mg base; eq 20mg base
Market Status	Prescription
Company	Forest Labs

2 of 2
Drug Name	Fetzima
PubMed Health	Levomilnacipran (By mouth)
Drug Classes	Antidepressant
Active Ingredient	Levomilnacipran hydrochloride
Dosage Form	Capsule, extended release
Route	Oral
Strength	eq 40mg base; eq 80mg base; eq 120mg base; eq 20mg base
Market Status	Prescription
Company	Forest Labs

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ACTIVE PHARMA INGREDIENTS

16 API Suppliers

10 USDMF

4 EU WC

7 NDC API

12 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

25 FDF Dossiers

20 FDA Orange Book

4 Canada

1 Listed Dossiers

DRUG PRODUCT COMPOSITIONS

CAPSULE, EXTENDED RELEASE;ORAL - EQ 120MG BASE

CAPSULE, EXTENDED RELEASE;ORAL - EQ 20MG BASE

CAPSULE, EXTENDED RELEASE;ORAL - EQ 40MG BASE

CAPSULE, EXTENDED RELEASE;ORAL - EQ 80MG BASE

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EXCIPIENTS BY APPLICATIONS

47 Coating Systems & Additives

24 Controlled & Modified Release

13 Fillers, Diluents & Binders

12 Film Formers & Plasticizers

9 Granulation

7 Solubilizers

6 Taste Masking

6 Direct Compression

5 Coloring Agents

5 Empty Capsules

4 Vegetarian Capsules

4 Thickeners and Stabilizers

3 API Stability Enhancers

3 Parenteral

2 Lubricants & Glidants

2 Co-Processed Excipients

2 Disintegrants & Superdisintegrants

1 Surfactant & Foaming Agents

1 Emulsifying Agents

1 Rheology Modifiers

1 Chewable & Orodispersible Aids

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4 Finished Drug Prices

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