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Chemistry

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Also known as: Miocamycin, Acecamycin, Miokamycin, Ponsinomycin, 3'',9-diacetylmydecamycin, 55881-07-7
Molecular Formula
C45H71NO17
Molecular Weight
898.0  g/mol
InChI Key
GQNZGCARKRHPOH-RQIKCTSVSA-N
FDA UNII
3T48CPS7U2

Miocamycin
Miocamycin is a macrolide type antimicrobial. This drug may be marketed in Japan for clinical use as it is listed in the Japanese pharmacopeia. It has shown to be effective against several gram-positive and gram-negative microbes and may be useful in the treatment of upper and lower respiratory tract infections, and urogenital tract infections or as an alternative to erythromycin treatment.
1 2D Structure

Miocamycin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
[(4R,5S,6S,7R,9R,10R,11E,13E,16R)-10-acetyloxy-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4-acetyloxy-4,6-dimethyl-5-propanoyloxyoxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate
2.1.2 InChI
InChI=1S/C45H71NO17/c1-13-34(50)59-33-23-36(52)55-26(4)18-16-15-17-19-32(58-29(7)48)25(3)22-31(20-21-47)41(42(33)54-12)62-44-39(53)38(46(10)11)40(27(5)57-44)61-37-24-45(9,63-30(8)49)43(28(6)56-37)60-35(51)14-2/h15-17,19,21,25-28,31-33,37-44,53H,13-14,18,20,22-24H2,1-12H3/b16-15+,19-17+/t25-,26-,27-,28+,31+,32+,33-,37+,38-,39-,40-,41+,42+,43+,44+,45-/m1/s1
2.1.3 InChI Key
GQNZGCARKRHPOH-RQIKCTSVSA-N
2.1.4 Canonical SMILES
CCC(=O)OC1CC(=O)OC(CC=CC=CC(C(CC(C(C1OC)OC2C(C(C(C(O2)C)OC3CC(C(C(O3)C)OC(=O)CC)(C)OC(=O)C)N(C)C)O)CC=O)C)OC(=O)C)C
2.1.5 Isomeric SMILES
CCC(=O)O[C@@H]1CC(=O)O[C@@H](C/C=C/C=C/[C@@H]([C@@H](C[C@@H]([C@@H]([C@H]1OC)O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C)O[C@H]3C[C@@]([C@H]([C@@H](O3)C)OC(=O)CC)(C)OC(=O)C)N(C)C)O)CC=O)C)OC(=O)C)C
2.2 Other Identifiers
2.2.1 UNII
3T48CPS7U2
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Maidimeisu

2. Midecamin

3. Midecamycin

4. Midecamycin Diacetate

5. Midekamycin

6. Midekamycin Acetate

7. Mosil

8. Mydecamycin

9. Myoxam

10. Neoisomidecamycin

11. Normicina

12. Sf 837

13. Sf-837

2.3.2 Depositor-Supplied Synonyms

1. Miocamycin

2. Acecamycin

3. Miokamycin

4. Ponsinomycin

5. 3'',9-diacetylmydecamycin

6. 55881-07-7

7. Midecamycin Acetate [jan]

8. Midecamycin Diacetate

9. 9,3''-di-o-acetylmidecamycin

10. Leucomycin V, 3b,9-diacetate 3,4b-dipropanoate

11. 3t48cps7u2

12. Mom

13. [(4r,5s,6s,7r,9r,10r,11e,13e,16r)-10-acetyloxy-6-[(2s,3r,4r,5s,6r)-5-[(2s,4r,5s,6s)-4-acetyloxy-4,6-dimethyl-5-propanoyloxyoxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] Propanoate

14. 9,3''-diacetylmidecamycin

15. Einecs 259-879-6

16. Unii-3t48cps7u2

17. Macroral

18. Miocamen

19. Mosil

20. Miocamycin (tn)

21. Miocamycin [mi]

22. Midecamycin Acetate (jp17)

23. Schembl139293

24. Chembl1091024

25. Dtxsid60905087

26. Leucomycin V, 3(sup B),9-diacetate 3,4(sup B)-dipropanoate

27. Midecamycin Acetate [who-dd]

28. Zinc169677000

29. 1532-rb

30. Leucomycinv,3b,9-diacetate3,4b-dipropanoate

31. D01636

32. Q3858659

33. W-105540

34. Midecamycin Acetate, Antibiotic For Culture Media Use Only

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 898.0 g/mol
Molecular Formula C45H71NO17
XLogP33.8
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count18
Rotatable Bond Count18
Exact Mass897.47219980 g/mol
Monoisotopic Mass897.47219980 g/mol
Topological Polar Surface Area218 Ų
Heavy Atom Count63
Formal Charge0
Complexity1590
Isotope Atom Count0
Defined Atom Stereocenter Count16
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


4.2 ATC Code

J - Antiinfectives for systemic use

J01 - Antibacterials for systemic use

J01F - Macrolides, lincosamides and streptogramins

J01FA - Macrolides

J01FA11 - Miocamycin


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ABOUT THIS PAGE

Miocamycin Manufacturers

A Miocamycin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Miocamycin, including repackagers and relabelers. The FDA regulates Miocamycin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Miocamycin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Miocamycin Suppliers

A Miocamycin supplier is an individual or a company that provides Miocamycin active pharmaceutical ingredient (API) or Miocamycin finished formulations upon request. The Miocamycin suppliers may include Miocamycin API manufacturers, exporters, distributors and traders.

Miocamycin GMP

Miocamycin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Miocamycin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Miocamycin GMP manufacturer or Miocamycin GMP API supplier for your needs.

Miocamycin CoA

A Miocamycin CoA (Certificate of Analysis) is a formal document that attests to Miocamycin's compliance with Miocamycin specifications and serves as a tool for batch-level quality control.

Miocamycin CoA mostly includes findings from lab analyses of a specific batch. For each Miocamycin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Miocamycin may be tested according to a variety of international standards, such as European Pharmacopoeia (Miocamycin EP), Miocamycin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Miocamycin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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