Mitoglitazone

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Also known as: 146062-49-9, Msdc-0160, Cay10415, 5-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione, Msdc 0160, Cay 10415

Molecular Formula

C₁₉H₁₈N₂O₄S

Molecular Weight

370.4 g/mol

InChI Key

IRNJSRAGRIZIHD-UHFFFAOYSA-N

FDA UNII

29I7RP18RG

Mitoglitazone has been used in trials studying the treatment of Type 2 Diabetes and Alzheimer's Disease.

1 2D Structure

Mitoglitazone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

5-[[4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

2.1.2 InChI

InChI=1S/C19H18N2O4S/c1-2-12-5-8-15(20-10-12)16(22)11-25-14-6-3-13(4-7-14)9-17-18(23)21-19(24)26-17/h3-8,10,17H,2,9,11H2,1H3,(H,21,23,24)

2.1.3 InChI Key

IRNJSRAGRIZIHD-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCC1=CN=C(C=C1)C(=O)COC2=CC=C(C=C2)CC3C(=O)NC(=O)S3

2.2 Other Identifiers

2.2.1 UNII

29I7RP18RG

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Msdc-0160

2.3.2 Depositor-Supplied Synonyms

1. 146062-49-9

2. Msdc-0160

3. Cay10415

4. 5-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione

5. Msdc 0160

6. Cay 10415

7. Cay-10415

8. Msd-9

9. 29i7rp18rg

10. Msdc0160

11. U-91325

12. 5-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)-benzyl)thiazolidine-2,4-dione

13. Pnu-91325

14. J730.386f

15. 2,4-thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-

16. 5-[[4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

17. Unii-29i7rp18rg

18. 2,4-thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)-2-oxoethoxy)phenyl)methyl)-

19. 5-({4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]phenyl}methyl)-1,3-thiazolidine-2,4-dione

20. Schembl622605

21. Us9562012, Mitoglitazone

22. Chembl146624

23. Schembl18538169

24. Chebi:94409

25. Gtpl11303

26. Mitoglitazone, >=98% (hplc)

27. Bdbm228129

28. Dtxsid301317736

29. Bcp16099

30. Ex-a1483

31. Wfa06249

32. Mfcd00916084

33. S7453

34. Akos026750561

35. Cs-6405

36. Db11721

37. Sb17325

38. Cay10415(msdc-0160)

39. Msdc-0160(cay10415)

40. Ac-32632

41. As-73799

42. Hy-100550

43. A899267

44. J-008189

45. Brd-a61858259-001-01-0

46. Q27166263

47. 5-[4-[2-(5-ethyl-2-pyridyl)-2-oxoethoxy]benzyl]-2,4-thiazolidinedione

48. 5-(4-(2-(5-ethyl-2-pyridinyl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione

49. 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione

50. 5-{4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione

51. 5- [[4- [2- (5- Ethyl- 2- Pyridinyl)- 2-oxoethoxy]phenyl]methyl]- 2, 4-thiazolidinedione

52. 5-[[4-[2-(5-ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione;msdc-0160

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₁₉H₁₈N₂O₄S
Molecular Weight	370.4 g/mol
XLogP3	3.5
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	7
Exact Mass	370.09872823 g/mol
Monoisotopic Mass	370.09872823 g/mol
Topological Polar Surface Area	111 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	534
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1