Find Mizolastine manufacturers, exporters & distributors on PharmaCompass

Mizolastine

Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 EU WC, 1 Listed Suppliers, $ API Reference Price

1 API Suppliers
1 EU WC
1 Listed Suppliers
$ API Reference Price

INTERMEDIATES

2 Intermediates Suppliers

2 Intermediates Suppliers

FINISHED DOSAGE FORMULATIONS

5 FDF Dossiers, 4 Europe, 1 South Africa

5 FDF Dossiers
4 Europe
1 South Africa

GLOBAL SALES INFORMATION

4 Finished Drug Prices

globalSalesInformation
4 Finished Drug Prices

MARKET PLACE

1 APIs, 1 Intermediates

marketPlace
1 APIs
1 Intermediates

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 108612-45-9, Mizollen, Zolistan, Sl 85.0324, Mistamine, 2-((1-(1-(p-fluorobenzyl)-2-benzimidazolyl)-4-piperidyl)methylamino)-4(3h)-pyrimidinone

Molecular Formula

C₂₄H₂₅FN₆O

Molecular Weight

432.5 g/mol

InChI Key

PVLJETXTTWAYEW-UHFFFAOYSA-N

FDA UNII

244O1F90NA

Mizolastine is under investigation in clinical trial NCT01928316 (A Bioequivalence Study of Domestic (Made in China) and Imported Mizolastine Tablets in Healthy Volunteers).

1 2D Structure

Mizolastine

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1H-pyrimidin-6-one

2.1.2 InChI

InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)

2.1.3 InChI Key

PVLJETXTTWAYEW-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CN(C1CCN(CC1)C2=NC3=CC=CC=C3N2CC4=CC=C(C=C4)F)C5=NC=CC(=O)N5

2.2 Other Identifiers

2.2.1 UNII

244O1F90NA

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Mistalin

2. Mistamine

3. Mizolen

4. Mizollen

5. Sl 85.0324

6. Sl-85.0324

7. Zolim

8. Zolistan

2.3.2 Depositor-Supplied Synonyms

1. 108612-45-9

2. Mizollen

3. Zolistan

4. Sl 85.0324

5. Mistamine

6. 2-((1-(1-(p-fluorobenzyl)-2-benzimidazolyl)-4-piperidyl)methylamino)-4(3h)-pyrimidinone

7. Mizolastine (mizollen)

8. Mkc-431

9. Chembl94454

10. 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methylamino]-1h-pyrimidin-6-one

11. Mistalin

12. 244o1f90na

13. Mizolastine [inn]

14. Ncgc00181013-01

15. Mizolastina

16. Mizolastinum

17. Mizolen

18. Zolim

19. Dsstox_cid_26801

20. Dsstox_rid_81916

21. Dsstox_gsid_46801

22. 2-((1-(1-(4-fluorobenzyl)-1h-benzo[d]imidazol-2-yl)piperidin-4-yl)(methyl)amino)pyrimidin-4(3h)-one

23. 2-[[1-[1-[(4-fluorophenyl)methyl]benzoimidazol-2-yl]-4-piperidyl]-methyl-amino]-3h-pyrimidin-4-one

24. Mizolastinum [inn-latin]

25. Mizolastina [inn-spanish]

26. Zolistam

27. 2-{1-[1-(4-fluorobenzyl)-1h-benzimidazol-2-yl]-4-piperidyl(methyl)amino}pyrimidin-4(1h)-one

28. Sl-85.0324

29. Mizollen (tn)

30. 2-((1-(1-(4-fluorobenzyl)-1h-benzo[d]imidazol-2-yl)-piperidin-4-yl)(methyl)amino)pyrimidin-4(1h)-one

31. Cas-108612-45-9

32. Mizolastine (jan/inn)

33. Mizolastine [inn:ban]

34. Unii-244o1f90na

35. Ccris 8410

36. Sl 850324

37. Mizolastine [mi]

38. Mizolastine [jan]

39. Schembl5061

40. Mizolastine [mart.]

41. Mizolastine [who-dd]

42. Mls006010068

43. Mkc431

44. Dtxsid5046801

45. Bdbm22877

46. Chebi:31857

47. Gtpl10102

48. Hms3713n04

49. Hy-b0164

50. Tox21_112663

51. Ac-634

52. Mfcd23140913

53. Zinc13831810

54. Akos005145756

55. Akos016003409

56. Tox21_112663_1

57. Ccg-220621

58. Cs-1997

59. Db12523

60. Ks-1139

61. Ncgc00344565-01

62. Ncgc00344565-04

63. 4(1h)-pyrimidinone, 2-((1-(1-((4-fluorophenyl)methyl)-1h-benzimidazol-2-yl)-4-piperidinyl)methylamino)-

64. Sl850324

65. Smr003965484

66. Sl-850324

67. Ft-0628955

68. M2756

69. D01117

70. T71584

71. Ab01566892_01

72. 612m459

73. A801901

74. Q417830

75. J-507624

76. Brd-k21884483-001-01-1

77. (4-ethoxy-2-oxo-2,5-dihydro-pyrrol-1-yl)-aceticacid

78. 2-({1-[1-(4-fluoro-benzyl)-1h-benzoimidazol-2-yl]-piperidin-4-yl}-methyl-amino)-3h-pyrimidin-4-one

79. 2-({1-[1-(4-fluorobenzyl)-1h-benzimidazol-2-yl]-piperidin-4-yl}-methylamino)-4(1h) Pyrimidinone

80. 2-[[1-[1-[(4-fluorophenyl)methyl]-2-benzimidazolyl]-4-piperidinyl]-methylamino]-1h-pyrimidin-6-one

81. 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]- Methylamino]-1h-pyrimidin-6-one

82. 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methyl-amino]-1h-pyrimidin-6-one

2.4 Create Date

2005-06-24

3 Chemical and Physical Properties

Molecular Formula	C₂₄H₂₅FN₆O
Molecular Weight	432.5 g/mol
XLogP3	3.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	5
Exact Mass	432.20738760 g/mol
Monoisotopic Mass	432.20738760 g/mol
Topological Polar Surface Area	65.8 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	728
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Histamine H1 Antagonists, Non-Sedating

A class of non-sedating drugs that bind to but do not activate histamine receptors (DRUG INVERSE AGONISM), thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment. (See all compounds classified as Histamine H1 Antagonists, Non-Sedating.)

4.2 ATC Code

R06AX25

S76 | LUXPHARMA | Pharmaceuticals Marketed in Luxembourg | Pharmaceuticals marketed in Luxembourg, as published by d'Gesondheetskeess (CNS, la caisse nationale de sante, www.cns.lu), mapped by name to structures using CompTox by R. Singh et al. (in prep.). List downloaded from https://cns.public.lu/en/legislations/textes-coordonnes/liste-med-comm.html. Dataset DOI:10.5281/zenodo.4587355

R - Respiratory system

R06 - Antihistamines for systemic use

R06A - Antihistamines for systemic use

R06AX - Other antihistamines for systemic use

R06AX25 - Mizolastine

API SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

EU WC

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Listed Suppliers

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

API Reference Price

[{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q3","strtotime":1630261800,"product":"PHARMACEUTICAL RAW MATERIALS MIZOLASTINE","address":"5TH FLOOR,LAXMI NARAYAN COMPLEX,10\/1 PALACE ROAD,","city":"BANGALORE","supplier":"BAL PHARMA","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"BANK ASIA LIMITED","customerCountry":"BANGLADESH","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"2006.2","totalValueFC":"5846.8","currency":"USD","unitRateINR":144548.66666666666,"date":"30-Aug-2021","totalValueINR":"433646","totalValueInUsd":"5846.8","indian_port":"BANGALORE AIR","hs_no":"29339990","bill_no":"4228336","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"BANGALORE AIR","supplierAddress":"5TH FLOOR,LAXMI NARAYAN COMPLEX,10\/1 PALACE ROAD,, BANGALORE","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2021","qtr":"Q4","strtotime":1634754600,"product":"MIZOLASTINE [I.H]","address":"PLOT NO. 705, ADITYA TRADE CENTREAMEERPET","city":"HYDERABAD ANDHRA PRADESH","supplier":"SHODHANA LABORATORIES PVT. LTD","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"BANK ASIA LIMITED","customerCountry":"BANGLADESH","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"1500","totalValueFC":"4365.1","currency":"USD","unitRateINR":109000,"date":"21-Oct-2021","totalValueINR":"327000","totalValueInUsd":"4365.1","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"5436278","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"PLOT NO. 705, ADITYA TRADE CENTREAMEERPET, HYDERABAD ANDHRA PRADESH","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q2","strtotime":1656441000,"product":"MIZOLASTINE [IH]","address":"KRISHE SAPPHIRE, 6TH FLOOR, 6B,MAD HAPUR VILLAGE SERILINGAMPALLI","city":"HYDERABAD,TELANGANA","supplier":"SHODHANA LABORATORIES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"ALEXANDRIA, EL NHOUZ","customer":"MEDIZEN PHARMACEUTICAL INDUSTRIES","customerCountry":"EGYPT","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"950","totalValueFC":"4473.5","currency":"USD","unitRateINR":69800,"date":"29-Jun-2022","totalValueINR":"349000","totalValueInUsd":"4473.5","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"2463750","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"KRISHE SAPPHIRE, 6TH FLOOR, 6B,MAD HAPUR VILLAGE SERILINGAMPALLI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1667154600,"product":"MIZOLASTINE [IH]","address":"KRISHE SAPPHIRE, 6TH FLOOR, 6B,MAD HAPUR VILLAGE SERILINGAMPALLI","city":"HYDERABAD,TELANGANA","supplier":"SHODHANA LABORATORIES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"MEGHNA BANK LTD.","customerCountry":"BANGLADESH","quantity":"100.00","actualQuantity":"100","unit":"KGS","unitRateFc":"1090","totalValueFC":"108599.2","currency":"USD","unitRateINR":89360,"date":"31-Oct-2022","totalValueINR":"8936000","totalValueInUsd":"108599.2","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"5141347","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"KRISHE SAPPHIRE, 6TH FLOOR, 6B,MAD HAPUR VILLAGE SERILINGAMPALLI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2022","qtr":"Q4","strtotime":1669573800,"product":"MIZOLASTINE [IH]","address":"KRISHE SAPPHIRE, 6TH FLOOR, 6B,MAD HAPUR VILLAGE SERILINGAMPALLI","city":"HYDERABAD,TELANGANA","supplier":"SHODHANA LABORATORIES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"ALEXANDRIA, EL NHOUZ","customer":"MEDIZEN PHARMACEUTICAL INDUSTRIES","customerCountry":"EGYPT","quantity":"17.00","actualQuantity":"17","unit":"KGS","unitRateFc":"915","totalValueFC":"15304","currency":"USD","unitRateINR":73470.588235294112,"date":"28-Nov-2022","totalValueINR":"1249000","totalValueInUsd":"15304","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"5763780","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"EGYPT","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"KRISHE SAPPHIRE, 6TH FLOOR, 6B,MAD HAPUR VILLAGE SERILINGAMPALLI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q2","strtotime":1682447400,"product":"MIZOLASTINE[IH]","address":"KRISHE SAPPHIRE, 6TH FLOOR, 6B,MAD HAPUR VILLAGE SERILINGAMPALLI","city":"HYDERABAD,TELANGANA","supplier":"SHODHANA LABORATORIES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"AL ARAFAH ISLAMI ","customerCountry":"BANGLADESH","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"1500","totalValueFC":"4417.1","currency":"USD","unitRateINR":120666.66666666667,"date":"26-Apr-2023","totalValueINR":"362000","totalValueInUsd":"4417.1","indian_port":"HYDERABAD AIR","hs_no":"29335990","bill_no":"9566731","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"HYDERABAD AIR","supplierAddress":"KRISHE SAPPHIRE, 6TH FLOOR, 6B,MAD HAPUR VILLAGE SERILINGAMPALLI, HYDERABAD,TELANGANA","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1701887400,"product":"PHARMACEUTICAL RAW MATERIALS \/API (ACTIVE PHARMA INGREDIENT) MIZOLASTINE","address":"5TH FLOOR,LAXMI NARAYAN COMPLEX,","city":"BANGALORE","supplier":"BAL PHARMA","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"M\/S","customerCountry":"BANGLADESH","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"2000","totalValueFC":"9850.7","currency":"USD","unitRateINR":164000,"date":"07-Dec-2023","totalValueINR":"820000","totalValueInUsd":"9850.7","indian_port":"Bangalore Air","hs_no":"29339990","bill_no":"5876759","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"Bangalore Air","supplierAddress":"5TH FLOOR,LAXMI NARAYAN COMPLEX,, BANGALORE","customerAddress":""},{"dataSource":"API Export","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722018600,"product":"MIZOLASTINE[IH]","address":"PLOT NO. 705, ADITYA TRADE CENTRE","city":"HYDERABAD ANDHRA PRADESH","supplier":"SHODHANA LABORATORIES PRIVATE LIMITED","supplierCountry":"INDIA","foreign_port":"DHAKA","customer":"AL-ARAFAH ISLAMI BANK PLC","customerCountry":"BANGLADESH","quantity":"5.50","actualQuantity":"5.5","unit":"KGS","unitRateFc":"1025","totalValueFC":"5506.9","currency":"USD","unitRateINR":83695.745454545453,"date":"27-Jul-2024","totalValueINR":"460326.6","totalValueInUsd":"5506.9","indian_port":"Hyderabad Air","hs_no":"29335990","bill_no":"2744384","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"BANGLADESH","selfForZScoreResived":"Pharma Grade","supplierPort":"Hyderabad Air","supplierAddress":"PLOT NO. 705, ADITYA TRADE CENTRE, HYDERABAD ANDHRA PRADESH","customerAddress":""}]