Granules India Limited has high volume world-class facilities for APIs, PFIs, & FDFs, serving customers in over 80 countries.

Contact Supplier

Jai Radhe Sales is your partner for all your sourcing needs.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

1 API Suppliers, 1 USDMF

1 API Suppliers
1 USDMF

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: Simvastatin ammonium salt, 139893-43-9, Simvastatin hydroxy acid ammonium salt, (3s,5s)-simvastatin hydroxy acid ammonium salt, 1-naphthaleneheptanoic acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-, ammonium salt (1:1), (betar,deltar,1s,2s,6r,8s,8ar)-, (3r,5r)-7-[(1s,2s,6r,8s,8ar)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid ammonium salt (tenivastatin ammonium salt)

Molecular Formula

C₂₅H₄₃NO₆

Molecular Weight

453.6 g/mol

InChI Key

FFPDWNBTEIXJJF-OKDJMAGBSA-N

1 2D Structure

Mls006010119

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid;azane

2.1.2 InChI

InChI=1S/C25H40O6.H3N/c1-6-25(4,5)24(30)31-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-18(26)13-19(27)14-22(28)29;/h7-8,11,15-16,18-21,23,26-27H,6,9-10,12-14H2,1-5H3,(H,28,29);1H3/t15-,16-,18+,19+,20-,21-,23-;/m0./s1

2.1.3 InChI Key

FFPDWNBTEIXJJF-OKDJMAGBSA-N

2.1.4 Canonical SMILES

CCC(C)(C)C(=O)OC1CC(C=C2C1C(C(C=C2)C)CCC(CC(CC(=O)O)O)O)C.N

2.1.5 Isomeric SMILES

CCC(C)(C)C(=O)O[C@H]1C[C@H](C=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@H](C[C@H](CC(=O)O)O)O)C.N

2.2 Synonyms

2.2.1 Depositor-Supplied Synonyms

1. Simvastatin Ammonium Salt

2. 139893-43-9

3. Simvastatin Hydroxy Acid Ammonium Salt

4. (3s,5s)-simvastatin Hydroxy Acid Ammonium Salt

5. 1-naphthaleneheptanoic Acid, 8-(2,2-dimethyl-1-oxobutoxy)-1,2,6,7,8,8a-hexahydro-beta,delta-dihydroxy-2,6-dimethyl-, Ammonium Salt (1:1), (betar,deltar,1s,2s,6r,8s,8ar)-

6. (3r,5r)-7-[(1s,2s,6r,8s,8ar)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid Ammonium Salt (tenivastatin Ammonium Salt)

7. Tenivastatin Ammonium Salt

8. Mls006010119

9. Akos025149640

10. Smr004701253

11. Q27266499

12. (3r,5r)-7-((1s,2s,6r,8s,8ar)-8-(2,2-dimethylbutanoyloxy)-2,6-dimethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl)-3,5-dihydroxyheptanoic Acid, Ammonia Salt

2.3 Create Date

2007-02-08

3 Chemical and Physical Properties

Molecular Formula	C₂₅H₄₃NO₆
Molecular Weight	453.6 g/mol
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	11
Exact Mass	453.30903809 g/mol
Monoisotopic Mass	453.30903809 g/mol
Topological Polar Surface Area	105 Å²
Heavy Atom Count	32
Formal Charge	0
Complexity	694
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2