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Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 1154028-82-6, Bay 85-3934, Molidustat (bay85-3934), Molidustat [inn], Molidustat [usan], Bay-85-3934
Molecular Formula
C13H14N8O2
Molecular Weight
314.30  g/mol
InChI Key
IJMBOKOTALXLKS-UHFFFAOYSA-N
FDA UNII
9JH486CZ13

Molidustat
Molidustat is under investigation in clinical trial NCT03350321 (A Study of Molidustat for Correction of Renal Anemia in Non-dialysis Subjects).
1 2D Structure

Molidustat

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(triazol-1-yl)-1H-pyrazol-3-one
2.1.2 InChI
InChI=1S/C13H14N8O2/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2,7-9,17H,3-6H2
2.1.3 InChI Key
IJMBOKOTALXLKS-UHFFFAOYSA-N
2.1.4 Canonical SMILES
C1COCCN1C2=NC=NC(=C2)N3C(=O)C(=CN3)N4C=CN=N4
2.2 Other Identifiers
2.2.1 UNII
9JH486CZ13
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2-(6-(morpholin-4-yl)pyrimidin-4-yl)-4-(1h-1,2,3-triazol-1-yl)-1,2-dihydro-3h-pyrazol-3-one

2. Bay 85-3934

2.3.2 Depositor-Supplied Synonyms

1. 1154028-82-6

2. Bay 85-3934

3. Molidustat (bay85-3934)

4. Molidustat [inn]

5. Molidustat [usan]

6. Bay-85-3934

7. Molidustat(bay 85-3934)

8. 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(triazol-1-yl)-1h-pyrazol-3-one

9. Bay85-3934

10. 9jh486cz13

11. 2-[6-(4-morpholinyl)-4-pyrimidinyl]-4-(1h-1,2,3-triazol-1-yl)-1,2-dihydro-3h-pyrazol-3-one

12. 3h-pyrazol-3-one, 1,2-dihydro-2-[6-(4-morpholinyl)-4-pyrimidinyl]-4-(1h-1,2,3-triazol-1-yl)-

13. 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)pyrazol-3-ol

14. 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1,2,3-triazol-1-yl)-1~{h}-pyrazol-3-one

15. 2-(6-(morpholin-4-yl)pyrimidin-4-yl)-4-(1h-1,2,3-triazol-1-yl)-1,2-dihydro-3h-pyrazol-3-one

16. Unii-9jh486cz13

17. Molidustat(bay85-3934)

18. 3h-pyrazol-3-one, 1,2-dihydro-2-(6-(4-morpholinyl)-4-pyrimidinyl)-4-(1h-1,2,3-triazol-1-yl)-

19. Qeq

20. Molidustat [who-dd]

21. Gtpl8456

22. Schembl2569970

23. Schembl6114312

24. Chembl3646118

25. Dtxsid80151089

26. Ex-a562

27. Molidustat (bay 85-3934)

28. Bdbm118339

29. Bcp14477

30. Who 9655

31. Mfcd28411428

32. Akos026750584

33. Zinc167006010

34. Bay-853934

35. Ccg-267626

36. Sb17156

37. Ncgc00388364-04

38. Ac-35448

39. As-74456

40. Hy-12654

41. Db-092822

42. S8138

43. A14404

44. Bay 85-3934;bay-85-3934

45. Us8653111, 72

46. Q27087553

47. 1-(6-morpholinopyrimidin-4-yl)-4-(1h-1,2,3-triazol-1-yl)-1h-pyrazol-5-ol

48. 2-(6-morpholinopyrimidin-4-yl)-4-(1h-1,2,3-triazol-1-yl)-1h-pyrazol-3(2h)-one

49. Molidustat;bay 85-3934;bay-85-3934; Bay 853934; Bay-853934; Bay853934

50. 2-(6-morpholin-4-ylpyrimidin-4-yl)-4-(1h-1,2,3-triazol-1-yl)-1,2-dihydro-3h-pyrazol-3-one

51. 2-[6-(morpholin-4-yl)pyrimidin-4-yl]-4-(1h-1,2,3-triazol-1-yl)-2,3-dihydro-1h-pyrazol-3-one

52. A1h

2.4 Create Date
2012-08-20
3 Chemical and Physical Properties
Molecular Weight 314.30 g/mol
Molecular Formula C13H14N8O2
XLogP3-0.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count3
Exact Mass314.12397172 g/mol
Monoisotopic Mass314.12397172 g/mol
Topological Polar Surface Area101 Ų
Heavy Atom Count23
Formal Charge0
Complexity481
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

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ABOUT THIS PAGE

Molidustat Manufacturers

A Molidustat manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Molidustat, including repackagers and relabelers. The FDA regulates Molidustat manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Molidustat API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Molidustat manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Molidustat Suppliers

A Molidustat supplier is an individual or a company that provides Molidustat active pharmaceutical ingredient (API) or Molidustat finished formulations upon request. The Molidustat suppliers may include Molidustat API manufacturers, exporters, distributors and traders.

click here to find a list of Molidustat suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Molidustat USDMF

A Molidustat DMF (Drug Master File) is a document detailing the whole manufacturing process of Molidustat active pharmaceutical ingredient (API) in detail. Different forms of Molidustat DMFs exist exist since differing nations have different regulations, such as Molidustat USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Molidustat DMF submitted to regulatory agencies in the US is known as a USDMF. Molidustat USDMF includes data on Molidustat's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Molidustat USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Molidustat suppliers with USDMF on PharmaCompass.

Molidustat GMP

Molidustat Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Molidustat GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Molidustat GMP manufacturer or Molidustat GMP API supplier for your needs.

Molidustat CoA

A Molidustat CoA (Certificate of Analysis) is a formal document that attests to Molidustat's compliance with Molidustat specifications and serves as a tool for batch-level quality control.

Molidustat CoA mostly includes findings from lab analyses of a specific batch. For each Molidustat CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Molidustat may be tested according to a variety of international standards, such as European Pharmacopoeia (Molidustat EP), Molidustat JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Molidustat USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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