Find Molindone manufacturers, exporters & distributors on PharmaCompass

Molindone

DRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

ACTIVE PHARMA INGREDIENTS

4 API Suppliers, 4 USDMF, 2 NDC API, 1 Listed Suppliers

4 API Suppliers
4 USDMF
2 NDC API
1 Listed Suppliers

FINISHED DOSAGE FORMULATIONS

15 FDF Dossiers, 12 FDA Orange Book, 3 Listed Dossiers

15 FDF Dossiers
12 FDA Orange Book
3 Listed Dossiers

RELATED EXCIPIENT COMPANIES

1 SPI Pharma, 1 DKSH, 3 Faran Shimi Pharmaceutical, 1 Boai NKY Pharmaceuticals Ltd, 10 Gangwal Healthcare, 1 Nanjing Well Pharmaceutical, 4 Anhui Sunhere Pharmaceutical Excipients Co.,Ltd, 9 BASF, 5 DFE Pharma, 5 Gangwal Chemicals, 1 Ideal Cures Pvt Ltd, 1 Ingredion Pharma Solutions, 17 Kerry, 10 Microlex e.U, 1 Novo Excipients, 3 Pharmatrans-Sanaq, 3 Pluviaendo, 3 Prachin Chemical, 9 Roquette, 2 Shanghai Shenmei Pharmaceutical Technology Co., Ltd, 10 Sigachi Industries, 3 Vasa Pharmachem

EXCIPIENTS BY APPLICATIONS

46 Fillers, Diluents & Binders, 23 Direct Compression, 15 Disintegrants & Superdisintegrants, 14 Granulation, 13 Thickeners and Stabilizers, 12 Lubricants & Glidants, 12 Co-Processed Excipients, 7 Controlled & Modified Release, 6 Solubilizers, 3 Emulsifying Agents, 3 Coating Systems & Additives, 3 Parenteral, 2 Taste Masking, 2 Chewable & Orodispersible Aids, 2 Film Formers & Plasticizers, 1 API Stability Enhancers, 1 Rheology Modifiers

excipientsByApplications
46 Fillers, Diluents & Binders
23 Direct Compression
15 Disintegrants & Superdisintegrants
14 Granulation
13 Thickeners and Stabilizers
12 Lubricants & Glidants
12 Co-Processed Excipients
7 Controlled & Modified Release
6 Solubilizers
3 Emulsifying Agents
3 Coating Systems & Additives
3 Parenteral
2 Taste Masking
2 Chewable & Orodispersible Aids
2 Film Formers & Plasticizers
1 API Stability Enhancers
1 Rheology Modifiers

GLOBAL SALES INFORMATION

1 US Medicaid Prescriptions

globalSalesInformation
1 US Medicaid Prescriptions

REF. STANDARDS & IMPURITIES

1 USP , 2 Others

otherSolutions
1 USP
2 Others

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

158,013

Annual Reports (USD Million)

Finished Drug Prices

103 RELATED EXCIPIENT COMPANIES

165EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 15622-65-8, Moban, Molindone hcl, Molindone (hydrochloride), En-1733a, Lidone

Molecular Formula

C₁₆H₂₅ClN₂O₂

Molecular Weight

312.83 g/mol

InChI Key

GQWNECFJGBQMBO-UHFFFAOYSA-N

FDA UNII

1DWS68PNE6

An indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of CLOZAPINE. (From AMA Drug Evaluations Annual, 1994, p283)

1 2D Structure

Molindone

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one;hydrochloride

2.1.2 InChI

InChI=1S/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H

2.1.3 InChI Key

GQWNECFJGBQMBO-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CCC1=C(NC2=C1C(=O)C(CC2)CN3CCOCC3)C.Cl

2.2 Other Identifiers

2.2.1 UNII

1DWS68PNE6

2.3 Synonyms

2.3.1 MeSH Synonyms

1. Hydrochloride, Molindone

2. Moban

3. Molindone

4. Molindone Monohydrochloride

5. Monohydrochloride, Molindone

2.3.2 Depositor-Supplied Synonyms

1. 15622-65-8

2. Moban

3. Molindone Hcl

4. Molindone (hydrochloride)

5. En-1733a

6. Lidone

7. 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4h-indol-4-one Hydrochloride

8. 1dws68pne6

9. 4h-indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, Monohydrochloride

10. Indol-4(5h)-one, 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-, Monohydrochloride

11. 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)indol-4(5h)-one Monohydrochloride

12. Dsstox_cid_25417

13. Dsstox_rid_80866

14. Dsstox_gsid_45417

15. Smr000499578

16. Unii-1dws68pne6

17. Molindone Hydrochloride [usan]

18. 3-ethyl-2-methyl-5-(4-morpholin-4-iumylmethyl)-1,5,6,7-tetrahydroindol-4-one Chloride; 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)indol-4(5h)-one Monohydrochloride; 3-ethyl-6,7-dihydro-2-methyl-5-morpholinomethylindol-4(5h)-one Hydrochloride;3-ethyl

19. En 1733a

20. Molindone Hydrochloride [usan:usp]

21. En 1733 A

22. Mfcd01718304

23. Molindonehydrochloride

24. Moban (tn)

25. Ncgc00016717-01

26. Cas-15622-65-8

27. Schembl41018

28. Mls001076677

29. Mls001333061

30. Mls001333062

31. Mls002222311

32. Molindone Hydrochloride (usp)

33. Chebi:6966

34. Chembl1200419

35. Dtxsid5045417

36. Hms1571o11

37. Hms3750c03

38. Bcp09555

39. Hy-b1017

40. Tox21_110579

41. Tox21_500665

42. S5481

43. 3-ethyl-6,7-dihydro-2-methyl-5-morpholinomethylindol-4(5h)-one Hydrochloride

44. Akos025401596

45. Tox21_110579_1

46. Ccg-213599

47. Cs-4531

48. Lp00665

49. Molindone Hydrochloride [mart.]

50. Molindone Hydrochloride [vandf]

51. Nc00658

52. 3-ethyl-2-methyl-5-(morpholin-4-ylmethyl)-1,5,6,7-tetrahydroindol-4-one;hydrochloride

53. Molindone Hydrochloride [usp-rs]

54. Molindone Hydrochloride [who-dd]

55. Ncgc00094027-01

56. Ncgc00162218-05

57. Ncgc00261350-01

58. Ac-22611

59. As-13875

60. Eu-0100665

61. Ft-0672453

62. M2252

63. Molindone Hydrochloride [orange Book]

64. En300-51039

65. Molindone Hydrochloride [usp Impurity]

66. D00796

67. Molindone Hydrochloride [usp Monograph]

68. T71854

69. Molindone Hydrochloride, >=98% (hplc), Solid

70. A849952

71. Sr-01000765437

72. J-009287

73. Sr-01000765437-3

74. Q27252301

75. Molindone Hydrochloride, United States Pharmacopeia (usp) Reference Standard

76. 3-ethyl-2-methyl-5-(morpholinomethyl)-6,7-dihydro-1h-indol-4(5h)-one Hydrochloride

77. 3-ethyl-2-methyl-5-morpholin-4-ylmethyl-1,5,6,7-tetrahydro-indol-4-one Hydrochloride

78. 3-ethyl-6,7-dihydro-2-methyl-5-(morpholinomethyl)-1h-indol-4(5h)-one Hydrochloride

79. 4h-indol-4-one, 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-, Hydrochloride (1:1)

80. 4h-indol-4-one,3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-,hydrochloride(1:1)

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₁₆H₂₅ClN₂O₂
Molecular Weight	312.83 g/mol
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	3
Exact Mass	312.1604557 g/mol
Monoisotopic Mass	312.1604557 g/mol
Topological Polar Surface Area	45.3 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	354
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	1
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	2

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Antipsychotic Agents

Agents that control agitated psychotic behavior, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect. They are used in SCHIZOPHRENIA; senile dementia; transient psychosis following surgery; or MYOCARDIAL INFARCTION; etc. These drugs are often referred to as neuroleptics alluding to the tendency to produce neurological side effects, but not all antipsychotics are likely to produce such effects. Many of these drugs may also be effective against nausea, emesis, and pruritus. (See all compounds classified as Antipsychotic Agents.)

4.2 FDA Pharmacological Classification

4.2.1 Pharmacological Classes

Typical Antipsychotic [EPC]

API SUPPLIERS