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    Chemistry

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    Also known as: 83919-23-7, Asmanex, Nasonex, Elocon, Monovo, Sch 32088
    Molecular Formula
    C27H30Cl2O6
    Molecular Weight
    521.4  g/mol
    InChI Key
    WOFMFGQZHJDGCX-ZULDAHANSA-N
    FDA UNII
    04201GDN4R
    Mometasone Furoate
    A pregnadienediol derivative ANTI-ALLERGIC AGENT and ANTI-INFLAMMATORY AGENT that is used in the management of ASTHMA and ALLERGIC RHINITIS. It is also used as a topical treatment for skin disorders.
    1 2D Structure

    Mometasone Furoate

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    [(8S,9R,10S,11S,13S,14S,16R,17R)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] furan-2-carboxylate
    2.1.2 InChI
    InChI=1S/C27H30Cl2O6/c1-15-11-19-18-7-6-16-12-17(30)8-9-24(16,2)26(18,29)21(31)13-25(19,3)27(15,22(32)14-28)35-23(33)20-5-4-10-34-20/h4-5,8-10,12,15,18-19,21,31H,6-7,11,13-14H2,1-3H3/t15-,18+,19+,21+,24+,25+,26+,27+/m1/s1
    2.1.3 InChI Key
    WOFMFGQZHJDGCX-ZULDAHANSA-N
    2.1.4 Canonical SMILES
    CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C
    2.1.5 Isomeric SMILES
    C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CCl)OC(=O)C5=CC=CO5)C)O)Cl)C
    2.2 Other Identifiers
    2.2.1 UNII
    04201GDN4R
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Asmanex

    2. Asmanex Twisthaler

    3. Elocon

    4. Furoate Monohydrate, Mometasone

    5. Furoate, Mometasone

    6. Mometasone

    7. Mometasone Furoate Monohydrate

    8. Monohydrate, Mometasone Furoate

    9. Nasonex

    10. Rinelon

    11. Sch 32088

    12. Sch-32088

    13. Sch32088

    14. Twisthaler, Asmanex

    2.3.2 Depositor-Supplied Synonyms

    1. 83919-23-7

    2. Asmanex

    3. Nasonex

    4. Elocon

    5. Monovo

    6. Sch 32088

    7. Mometasone 17-furoate

    8. Sinuva

    9. Mometasone Furoate Anhydrous

    10. Sch32088

    11. Sch-32088

    12. Nsc-746171

    13. Chembl1161

    14. Lyr210

    15. (8s,9r,10s,11s,13s,14s,16r,17r)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3h-cyclopenta[a]phenanthren-17-yl Furan-2-carboxylate

    16. [(8s,9r,10s,11s,13s,14s,16r,17r)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] Furan-2-carboxylate

    17. Chebi:47564

    18. Lyr-210

    19. 04201gdn4r

    20. Nsc-760077

    21. (11beta,16alpha)-9,21-dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

    22. Danitin

    23. Ecural

    24. Elomet

    25. Dsstox_cid_3333

    26. Asmanex Twisthaler

    27. Dsstox_rid_76981

    28. Dsstox_gsid_23333

    29. (9beta,10alpha,11alpha,14beta,16alpha,17alpha)-9,21-dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate

    30. 9,21-dichloro-11beta-hydroxy-16alpha-methyl-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate

    31. Elocone

    32. Flumeta

    33. Nosorex

    34. Rimelon

    35. Ovixan

    36. Asmanex Hfa

    37. Mometasone Fuorate

    38. Mof

    39. Unii-04201gdn4r

    40. Mometasone-furoate

    41. Ncgc00016950-01

    42. Prestwick_924

    43. Asmanex (tn)

    44. Mometasone Furoate [usan:usp:jan]

    45. Cas-83919-23-7

    46. Elocon (tn)

    47. Las 41002

    48. Brn 4340538

    49. Prestwick0_000572

    50. Prestwick1_000572

    51. Prestwick2_000572

    52. Prestwick3_000572

    53. Mometasone Furancarboxylate

    54. Schembl4568

    55. Bspbio_000384

    56. Mometasone 17-(2-furoate)

    57. Mls002153879

    58. Spbio_002603

    59. Mometasone Furoate (jan/usp)

    60. Bpbio1_000424

    61. Mometasone Furoate [mi]

    62. Dtxsid4023333

    63. Mometasone Furoate [jan]

    64. Mometasone Furoate [usan]

    65. Hms1569d06

    66. Hms2096d06

    67. Hms2235i14

    68. Hms3713d06

    69. Mometasone Furoate [vandf]

    70. Mometasone Furoate [mart.]

    71. Mometasone Furoate [usp-rs]

    72. Mometasone Furoate [who-dd]

    73. Zinc3938677

    74. Tox21_110705

    75. Ac-941

    76. Bdbm50148733

    77. Mfcd00866003

    78. Nsc746171

    79. S1987

    80. Mometasone Furoate, >=98% (hplc)

    81. Akos015994732

    82. Tox21_110705_1

    83. Ccg-220572

    84. Db14512

    85. Ks-1275

    86. Mometasone Furoate [green Book]

    87. Nsc 746171

    88. Nsc 760077

    89. 9,21-dichloro-11beta,17-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 17-(2-furoate)

    90. Mometasone Furoate [orange Book]

    91. Mometasone Furoate [ep Monograph]

    92. Ncgc00179578-01

    93. Ncgc00179578-03

    94. Ncgc00179578-04

    95. (11beta,16alpha)-9,21-dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl Furan-2-carboxylate

    96. Dulera Component Mometasone Furoate

    97. Hy-13693

    98. Mometasone Furoate [usp Monograph]

    99. Smr001233233

    100. M2354

    101. Mometasone Furoate Component Of Dulera

    102. C07817

    103. D00690

    104. Mometasone Furoate 1000 Microg/ml In Methanol

    105. 919m237

    106. A840685

    107. Mometasone Furoate 100 Microg/ml In Acetonitrile

    108. Sr-01000841209

    109. Lyr-220 Active Component Mometasone Furoate

    110. Q-101380

    111. Q1044248

    112. Sr-01000841209-2

    113. Brd-k60640630-001-03-7

    114. Brd-k60640630-001-11-0

    115. Mometasone Furoate, European Pharmacopoeia (ep) Reference Standard

    116. Mometasone Furoate, United States Pharmacopeia (usp) Reference Standard

    117. 11?,16?)-9,21-dichloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl 2-furoate

    118. Mometasone Furoate, Pharmaceutical Secondary Standard; Certified Reference Material

    119. (11.beta.,16.alpha.)-9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

    120. [(8s,9r,10s,11s,13s,14s,16r,17r)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] Furan-2-carboxylate;mometasone Furoate

    121. [(9r,10s,11s,13s,16r,17r)-9-chloro-17-(2-chloroacetyl)-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] Furan-2-carboxylate

    122. 9,21-dichloro-11.beta.,17-dihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione 17-(2-furoate)

    123. Pregna-1,20-dione, 9,21-dichloro-17-[(2-furanylcarbonyl)oxy]-11-hydroxy-16-methyl-, (11.beta.,16.alpha.)-

    124. Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methyl-, (11.beta.,16.alpha.)

    125. Pregna-1,4-diene-3,20-dione, 9,21-dichloro-17-((2-furanylcarbonyl)oxy)-11-hydroxy-16-methyl-, (11beta,16alpha)-

    2.4 Create Date
    2005-06-24
    3 Chemical and Physical Properties
    Molecular Weight 521.4 g/mol
    Molecular Formula C27H30Cl2O6
    XLogP33.9
    Hydrogen Bond Donor Count1
    Hydrogen Bond Acceptor Count6
    Rotatable Bond Count5
    Exact Mass520.1419441 g/mol
    Monoisotopic Mass520.1419441 g/mol
    Topological Polar Surface Area93.8 Ų
    Heavy Atom Count35
    Formal Charge0
    Complexity1020
    Isotope Atom Count0
    Defined Atom Stereocenter Count8
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count1
    4 Drug and Medication Information
    4.1 Drug Information
    1 of 6  
    Drug NameElocon
    Drug LabelELOCON (mometasone furoate) Ointment, 0.1% contains mometasone furoate for topical use. Mometasone furoate is a synthetic corticosteroid with anti-inflammatory activity.Chemically, mometasone furoate is 9,21-dichloro-11,17-dihydroxy-16-methylpr...
    Active IngredientMometasone furoate
    Dosage FormLotion; Ointment; Cream
    RouteTopical
    Strength0.1%
    Market StatusPrescription
    CompanyMerck Sharp Dohme

    2 of 6  
    Drug NameMometasone furoate
    PubMed HealthMometasone
    Drug ClassesAnti-Inflammatory, Corticosteroid, Strong
    Drug LabelMometasone furoate, the active component of the ASMANEX TWISTHALER product, is a corticosteroid with the chemical name 9,21-dichloro-11(Beta),17-dihydroxy-16(alpha)-methylpregna-1,4-diene-3,20-dione 17-(2-furoate) and the following chemical structure...
    Active IngredientMometasone furoate
    Dosage FormOintment; Cream; Lotion
    RouteTopical
    Strength0.1%
    Market StatusPrescription
    CompanyTaro; Glenmark Generics; Fougera Pharms; Perrigo; Perrigo New York; Tolmar; G And W Labs

    3 of 6  
    Drug NameNasonex
    Drug LabelMometasone furoate monohydrate, the active component of NASONEX Nasal Spray, 50 mcg, is an anti-inflammatory corticosteroid having the chemical name, 9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione17-(2 furoate) monohydrate, an...
    Active IngredientMometasone furoate monohydrate
    Dosage FormSpray, metered
    RouteNasal
    Strengtheq 0.05mg base/spray
    Market StatusPrescription
    CompanyMerck Sharp Dohme

    4 of 6  
    Drug NameElocon
    Drug LabelELOCON (mometasone furoate) Ointment, 0.1% contains mometasone furoate for topical use. Mometasone furoate is a synthetic corticosteroid with anti-inflammatory activity.Chemically, mometasone furoate is 9,21-dichloro-11,17-dihydroxy-16-methylpr...
    Active IngredientMometasone furoate
    Dosage FormLotion; Ointment; Cream
    RouteTopical
    Strength0.1%
    Market StatusPrescription
    CompanyMerck Sharp Dohme

    5 of 6  
    Drug NameMometasone furoate
    PubMed HealthMometasone
    Drug ClassesAnti-Inflammatory, Corticosteroid, Strong
    Drug LabelMometasone furoate, the active component of the ASMANEX TWISTHALER product, is a corticosteroid with the chemical name 9,21-dichloro-11(Beta),17-dihydroxy-16(alpha)-methylpregna-1,4-diene-3,20-dione 17-(2-furoate) and the following chemical structure...
    Active IngredientMometasone furoate
    Dosage FormOintment; Cream; Lotion
    RouteTopical
    Strength0.1%
    Market StatusPrescription
    CompanyTaro; Glenmark Generics; Fougera Pharms; Perrigo; Perrigo New York; Tolmar; G And W Labs

    6 of 6  
    Drug NameNasonex
    Drug LabelMometasone furoate monohydrate, the active component of NASONEX Nasal Spray, 50 mcg, is an anti-inflammatory corticosteroid having the chemical name, 9,21-Dichloro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione17-(2 furoate) monohydrate, an...
    Active IngredientMometasone furoate monohydrate
    Dosage FormSpray, metered
    RouteNasal
    Strengtheq 0.05mg base/spray
    Market StatusPrescription
    CompanyMerck Sharp Dohme

    4.2 Drug Indication

    There are 3 formulations of mometasone furoate with various indications. The inhaler is indicated for prophylaxis of asthma in patients 4 years. The nasal spray is indicated for treating nasal symptoms of allergic rhinitis in patients 2 years, treating symptoms of nasal congestion from seasonal allergic rhinitis in patients 2 years, treating nasal polyps in patients 18 years, and prophylaxis of seasonal allergic rhinitis in patients 12 years. The ointment is indicated for symptomatic treatment of dermatitis and pruritis in patients 2 years.

    FDA Label

    Seasonal and perennial allergic rhinitis

    5 Pharmacology and Biochemistry
    5.1 Pharmacology

    Mometasone is a synthetic corticosteroid with an affinity for glucocorticoid receptors 22 times higher than that of [dexamethasone]. Mometasone furoate also has a lower affinity to mineralocorticoid receptors than natural corticosteroids, making it more selective in its action. Mometasone furoate diffuses across cell membranes to activate pathways responsible for reducing inflammation.

    5.2 MeSH Pharmacological Classification

    Anti-Inflammatory Agents

    Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)

    Dermatologic Agents

    Drugs used to treat or prevent skin disorders or for the routine care of skin. (See all compounds classified as Dermatologic Agents.)

    Anti-Allergic Agents

    Agents that are used to treat allergic reactions. Most of these drugs act by preventing the release of inflammatory mediators or inhibiting the actions of released mediators on their target cells. (From AMA Drug Evaluations Annual, 1994, p475) (See all compounds classified as Anti-Allergic Agents.)

    5.3 FDA Pharmacological Classification
    5.3.1 Pharmacological Classes
    Corticosteroid Hormone Receptor Agonists [MoA]; Corticosteroid [EPC]; Corticosteroid Hormone Receptor Agonists [MoA]
    5.4 Absorption, Distribution and Excretion

    Absorption

    The mean time to peak concentration is 1.0 to 2.5 hours. Bioavailability has been reported as <1% but studies of repeat doses of inhaled corticosteroids suggest a bioavailability of 11%. The 0.1% ointment may have a bioavailability of 0.7%.

    Route of Elimination

    For an inhaled dose, approximately 74% is excreted in the feces and 8% is excreted in the urine.

    Volume of Distribution

    Steady state volume of distribution of 152L.

    Clearance

    The clearance rate of mometasone furoate is not readily available, though it may be close to 90L/h.

    5.5 Metabolism/Metabolites

    Metabolism of mometasone furoate is largely performed hepatically by cytochrome P450 3A4 producing a number of metabolites. Some of these metabolites include free mometasone and 6-beta-hydroxy-mometasone furoate.

    5.6 Biological Half-Life

    The terminal half life of an inhaled dose is approximately 5 hours though it has been reported as 5.8 hours by other sources.

    5.7 Mechanism of Action

    In asthma, mometasone is believed to inhibit mast cells, eosinophils, basophils, and lymphocytes. There is also evidence of inhibition of histamine, leukotrienes, and cytokines. Corticosteroids diffuse across cell membranes into the cytosol of cells where they bind to glucocorticoid receptors to produce their activity. Mometasone furoate has a particularly high receptor affinity compare to other corticosteroids, 22 times higher than that of [dexamethasone]. Mometasone furoate binding to a glucocorticoid receptor causes conformational changes in the receptor, separation from chaperones, and the receptor moves to the nucleus. Once at the nucleus, receptors dimerize and bind to a DNA sequence known as the glucocorticoid response element which either increases expression of anti-inflammatory molecules or inhibits expression of pro-inflammatory molecules (such as interleukins 4 and 5). Mometasone furoate also reduces inflammation by blocking transcription factors such as activator-protein-1 and nuclear factor kappa B (NF-kappaB).

    API Reference Price

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MTC-002\/22 L22405A1)","address":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:","city":"MUMBAI","supplier":"STERLING SPA","supplierCountry":"ITALY","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.00","actualQuantity":"1","unit":"KGS","unitRateFc":"5200","totalValueFC":"5436.2","currency":"EUR","unitRateINR":"447980","date":"13-Dec-2022","totalValueINR":"447980","totalValueInUsd":"5436.2","indian_port":"BOMBAY AIR","hs_no":"29372900","bill_no":"3723389","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS 22 BHULABHAI DESAI ROAD Contact No:"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q3","strtotime":1693333800,"product":"MOMETASONE FUROATE MICRONIZED EP, BATCH NO MTC-002\/22 L22405A1","address":"B\/2 MAHALAXMI CHAMBERS,22 BHULABHA I DESAI ROAD","city":"MUMBAI","supplier":"STERLING S P A","supplierCountry":"ITALY","foreign_port":"NA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"5200","totalValueFC":"11508.6","currency":"EUR","unitRateINR":"471898.2","date":"30-Aug-2023","totalValueINR":"953329.691","totalValueInUsd":"11508.6","indian_port":"DELHI AIR","hs_no":"29372900","bill_no":"0","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"NA","supplierAddress":"","customerAddress":"B\/2 MAHALAXMI CHAMBERS,22 BHULABHA I DESAI ROAD"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q4","strtotime":1703269800,"product":"MOMETASONE FUROATE MICRONIZED(QTY:300GMS, VALUE:USD 4800)","address":"H.NO. 8-2-337,BESIDE TV9 OFFICE","city":"HYDERABAD ANDHRA PRADESH","supplier":"STERLING SPA","supplierCountry":"ITALY","foreign_port":"ROME","customer":"DR. REDDY\\'S LABORATORIES","customerCountry":"INDIA","quantity":"0.30","actualQuantity":"0.3","unit":"KGS","unitRateFc":"16000","totalValueFC":"4832.1","currency":"USD","unitRateINR":"1340800","date":"23-Dec-2023","totalValueINR":"402240","totalValueInUsd":"4832.1","indian_port":"Hyderabad Air","hs_no":"29372200","bill_no":"9382674","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA, 30 SOLOMEO 06073 CORCIANO- PERUGIA ITALY Perugia, , Italy Italy","customerAddress":"H.NO. 8-2-337,BESIDE TV9 OFFICE"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1704911400,"product":"MOMETASONE FUROATE","address":"OFFICE NO. 606,607,608, Shapath-5,","city":"AHMEDABAD","supplier":"Y.S.P. INDUSTRIES M SDN BHD","supplierCountry":"MALAYSIA","foreign_port":"KUALA LUMPUR - INT\\'L","customer":"JAMP INDIA PHARMACEUTICALS PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.45","actualQuantity":"0.449","unit":"KGS","unitRateFc":"1000","totalValueFC":"551.3","currency":"USD","unitRateINR":"102047.8","date":"11-Jan-2024","totalValueINR":"45819.47","totalValueInUsd":"551.3","indian_port":"Hyderabad Air","hs_no":"29379090","bill_no":"9628282","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"MALAYSIA","selfForZScoreResived":"Pharma Grade","supplierPort":"KUALA LUMPUR - INT\\'L","supplierAddress":"LOT 3,5 &7 JALAN P\/7,SECTION 13,KAWASAN PERINDUSTRIAN BANDAR BARU BANGI KAJANG,SELANGOR 43000 Malaysia","customerAddress":"OFFICE NO. 606,607,608, Shapath-5,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q1","strtotime":1708453800,"product":"MOMETASONE FUROATE MONOHYDRATE GRADE I","address":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"HAVIONE FARMACIENCIA S A","supplierCountry":"PORTUGAL","foreign_port":"LISBOA","customer":"APL HEALTHCARE","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"50000","totalValueFC":"101116.3","currency":"USD","unitRateINR":"4195000","date":"21-Feb-2024","totalValueINR":"8390000","totalValueInUsd":"101116.3","indian_port":"APIIC MULTI PRODUCT SEZ NAIDUPET AP","hs_no":"29372900","bill_no":"1000224","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBOA","supplierAddress":"N\/A","customerAddress":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1712687400,"product":"MOMETASONE FUROATE ANHYDROUS IP MICRON","address":"TORRENT HOUSE,","city":"AHMEDABAD. GUJARAT","supplier":"M\/S. ORGANON INTERNATIONAL SERVICES GMBH","supplierCountry":"SINGAPORE","foreign_port":"SINGAPORE","customer":"TORRENT PHARMACEUTICALS LIMITED","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"56000","totalValueFC":"282879.8","currency":"USD","unitRateINR":"4724505.5","date":"10-Apr-2024","totalValueINR":"23622527.55","totalValueInUsd":"282879.8","indian_port":"Bombay Air","hs_no":"29372200","bill_no":"2962480","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SINGAPORE","selfForZScoreResived":"Pharma Grade","supplierPort":"SINGAPORE","supplierAddress":"WEYSTRASSE 20 CH-6006 LUCERNE-6006SDNFSDNF SINGAPORE","customerAddress":"TORRENT HOUSE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1713983400,"product":"MOMETASONE FUROATE MICRONIZED","address":"159, C.S.T. ROAD,","city":"MUMBAI,MAHARASHTRA","supplier":"STERLING SPA","supplierCountry":"ITALY","foreign_port":"N\/A","customer":"LUPIN LTD","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"10295.3","totalValueFC":"52026.6","currency":"USD","unitRateINR":"868920.4","date":"25-Apr-2024","totalValueINR":"4344602","totalValueInUsd":"52026.6","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372200","bill_no":"1002880","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"N\/A","supplierAddress":"VIA DELLA CARBONERIA 30 06073 SOLOMEO DI CORCIANO - PG , ITALY","customerAddress":"159, C.S.T. ROAD,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1716057000,"product":"MOMETASONE FUROATE BP (MICRONIZED) BATCH NO MTC-001\/23 L23178A1","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"STERLING SPA","supplierCountry":"ITALY","foreign_port":"ROME","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2000","unit":"GMS","unitRateFc":"5.2","totalValueFC":"11541.1","currency":"EUR","unitRateINR":"481","date":"19-May-2024","totalValueINR":"962000","totalValueInUsd":"11541.1","indian_port":"Delhi Air","hs_no":"29372900","bill_no":"3559847","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA, 30 SOLOMEO 06073 CORCIANO PERUGIA - ITALY ., .,ITALY ITALY","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1716143400,"product":"MOMETASONE FUROATE MONOHYDRATE GRADE I","address":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD, ANDHRA PRADESH","supplier":"HAVIONE FARMACIENCIA S A","supplierCountry":"PORTUGAL","foreign_port":"LISBOA","customer":"APL HEALTHCARE","customerCountry":"INDIA","quantity":"3.00","actualQuantity":"3","unit":"KGS","unitRateFc":"50000","totalValueFC":"151792","currency":"USD","unitRateINR":"4217500","date":"20-May-2024","totalValueINR":"12652500","totalValueInUsd":"151792","indian_port":"APIIC MULTI PRODUCT SEZ NAIDUPET AP","hs_no":"29372900","bill_no":"1000707","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBOA","supplierAddress":"N\/A","customerAddress":"3RD FLOOR, PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1716489000,"product":"MOMETASONE FUROATE MONOHYDRATE GRADE I (QTY : 0.300KG, VALUE: USD 15000)","address":"PLOT NO.2, MAITRIVIHAR,","city":"HYDERABAD\/ANDHRA PRADESH","supplier":"HOVIONE","supplierCountry":"PORTUGAL","foreign_port":"LISBON","customer":"AUROBINDO PHARMA LIMITED","customerCountry":"INDIA","quantity":"0.30","actualQuantity":"0.3","unit":"KGS","unitRateFc":"50000","totalValueFC":"15179.2","currency":"USD","unitRateINR":"4217500","date":"24-May-2024","totalValueINR":"1265250","totalValueInUsd":"15179.2","indian_port":"Hyderabad Air","hs_no":"29372200","bill_no":"3634485","productDescription":"API","marketType":"REGULATED MARKET","country":"PORTUGAL","selfForZScoreResived":"Pharma Grade","supplierPort":"LISBON","supplierAddress":"SETE CASAS 2674-506 LOURES PORTUGALSDNFSDNF Portugal","customerAddress":"PLOT NO.2, MAITRIVIHAR,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q2","strtotime":1717180200,"product":"MOMETASONE FUROATE BP (MICRONIZED) BATCH NO- MTC-002\/23 L24082A1","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"STERLING SPA","supplierCountry":"ITALY","foreign_port":"ROME","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.40","actualQuantity":"400","unit":"GMS","unitRateFc":"5.2","totalValueFC":"2304.8","currency":"EUR","unitRateINR":"481","date":"01-Jun-2024","totalValueINR":"192400","totalValueInUsd":"2304.8","indian_port":"Delhi Air","hs_no":"29372900","bill_no":"3774029","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA, 30 SOLOMEO 06073 CORCIANO PERUGIA - ITALY ., .,ITALY ITALY","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1722450600,"product":"MOMETASONE FUROATE(API) (MOMETASONE FUROATE MICRONIZED EP AND USP) (BATCH NO.MTC-003\/22 L23024A1)","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"STERLING SPA","supplierCountry":"ITALY","foreign_port":"ROME","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"0.05","actualQuantity":"0.05","unit":"KGS","unitRateFc":"5200","totalValueFC":"287.3","currency":"EUR","unitRateINR":"482040","date":"01-Aug-2024","totalValueINR":"24102","totalValueInUsd":"287.3","indian_port":"Bombay Air","hs_no":"29372900","bill_no":"4812767","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA 30 06073 SOLOMEO DI CORCIANO-PG ITALY, , ItalySDNF Italy","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1724956200,"product":"MOMETASONE FUROATE ANHYDROUS IP MICRON","address":"TORRENT HOUSE,","city":"AHMEDABAD. GUJARAT","supplier":"M\/S. ORGANON INTERNATIONAL SERVICES GMBH","supplierCountry":"SINGAPORE","foreign_port":"SINGAPORE","customer":"TORRENT PHARMACEUTICALS LIMITED","customerCountry":"INDIA","quantity":"5.00","actualQuantity":"5","unit":"KGS","unitRateFc":"56000","totalValueFC":"283242.9","currency":"USD","unitRateINR":"4751600","date":"30-Aug-2024","totalValueINR":"23758000","totalValueInUsd":"283242.9","indian_port":"Bombay Air","hs_no":"29372200","bill_no":"5336467","productDescription":"API","marketType":"LESS REGULATED MARKET","country":"SINGAPORE","selfForZScoreResived":"Pharma Grade","supplierPort":"SINGAPORE","supplierAddress":"WEYSTRASSE 20 CH-6006 LUCERNE-6006SDNFSDNF SWITZERLAND","customerAddress":"TORRENT HOUSE,"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q3","strtotime":1725820200,"product":"MOMETASONE FUROATE BP (MICRONIZED) BATCH NO- MTC-002\/24 L24292A1","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"STERLING SPA","supplierCountry":"ITALY","foreign_port":"ROME","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2000","unit":"GMS","unitRateFc":"5.2","totalValueFC":"11758.8","currency":"EUR","unitRateINR":"492.7","date":"09-Sep-2024","totalValueINR":"985400","totalValueInUsd":"11758.8","indian_port":"Delhi Air","hs_no":"29372900","bill_no":"5494267","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME","supplierAddress":"VIA DELLA CARBONERIA, 30 SOLOMEO 06 073 CORCIANO PERUGIA - ITALY ., ., ITALY ITALY ITALY","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1728066600,"product":"MOMETASONE FUROATE MONOHYDRATE, BATCH NO PR242065 (MOMETASONE FUROATE MONOHYDRATE MICRONIZE)","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"CHEMO","supplierCountry":"ITALY","foreign_port":"MILAN - MALPENSA","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"1.01","actualQuantity":"1010","unit":"GMS","unitRateFc":"11.5","totalValueFC":"11728.8","currency":"USD","unitRateINR":"975.8","date":"05-Oct-2024","totalValueINR":"985532.75","totalValueInUsd":"11728.8","indian_port":"Delhi Air","hs_no":"29372900","bill_no":"5965582","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"MILAN - MALPENSA","supplierAddress":"MANUEL POMBO AGULO 28 3RD FLOOR 280 50 MADRID SDNF SPAIN","customerAddress":"B\/2 MAHALAXMI CHAMBERS"},{"dataSource":"API Import","activeIngredients":"","year":"2024","qtr":"Q4","strtotime":1731263400,"product":"MOMETASONE FUROATE MICRONIZED USP AND EP","address":"B\/2 MAHALAXMI CHAMBERS","city":"MUMBAI. MAHARASHTRA","supplier":"STERLING SPA","supplierCountry":"ITALY","foreign_port":"ROME (ROMA), RM","customer":"GLENMARK PHARMACEUTICALS","customerCountry":"INDIA","quantity":"2.00","actualQuantity":"2","unit":"KGS","unitRateFc":"5742.9","totalValueFC":"11596.3","currency":"USD","unitRateINR":"489294","date":"11-Nov-2024","totalValueINR":"978588","totalValueInUsd":"11596.3","indian_port":"Indore-EPZ\/SEZ","hs_no":"29372200","bill_no":"1007872","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Micronized","supplierPort":"ROME (ROMA), RM","supplierAddress":"VIA DELLA CARBONERIA 30 06073 SOLOM EO DI CORCIANO-PG ITALY, , Italy Italy","customerAddress":"B\/2 MAHALAXMI CHAMBERS"}]
    05-Jan-2021
    28-Dec-2024
    KGS
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    Average Price (USD/KGS)

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    DRUG PRODUCT COMPOSITIONS

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    DOSAGE - OINTMENT;TOPICAL - 0.1%

    USFDA APPLICATION NUMBER - 19543

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    DOSAGE - CREAM;TOPICAL - 0.1% **Federal Regis...DOSAGE - CREAM;TOPICAL - 0.1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19625

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    DOSAGE - LOTION;TOPICAL - 0.1% **Federal Regi...DOSAGE - LOTION;TOPICAL - 0.1% **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 19796

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.05MG...DOSAGE - AEROSOL, METERED;INHALATION - 0.05MG/INH

    USFDA APPLICATION NUMBER - 205641

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.10MG...DOSAGE - AEROSOL, METERED;INHALATION - 0.10MG/INH

    USFDA APPLICATION NUMBER - 205641

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.20MG...DOSAGE - AEROSOL, METERED;INHALATION - 0.20MG/INH

    USFDA APPLICATION NUMBER - 205641

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    DOSAGE - SPRAY, METERED;NASAL - 0.05MG/SPRAY ...DOSAGE - SPRAY, METERED;NASAL - 0.05MG/SPRAY **Federal Register determination that product was not discontinued or withdrawn for safety or effectiveness reasons**

    USFDA APPLICATION NUMBER - 20762

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    DOSAGE - POWDER;INHALATION - 0.11MG/INH

    USFDA APPLICATION NUMBER - 21067

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    DOSAGE - POWDER;INHALATION - 0.22MG/INH

    USFDA APPLICATION NUMBER - 21067

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.05MG/INH

    USFDA APPLICATION NUMBER - 22518

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.1MG/INH

    USFDA APPLICATION NUMBER - 22518

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    DOSAGE - AEROSOL, METERED;INHALATION - 0.005M...DOSAGE - AEROSOL, METERED;INHALATION - 0.005MG/INH;0.2MG/INH

    USFDA APPLICATION NUMBER - 22518

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    USP

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    ABOUT THIS PAGE

    Mometasone Furoate Manufacturers

    A Mometasone Furoate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mometasone Furoate, including repackagers and relabelers. The FDA regulates Mometasone Furoate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mometasone Furoate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

    click here to find a list of Mometasone Furoate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

    Mometasone Furoate Suppliers

    A Mometasone Furoate supplier is an individual or a company that provides Mometasone Furoate active pharmaceutical ingredient (API) or Mometasone Furoate finished formulations upon request. The Mometasone Furoate suppliers may include Mometasone Furoate API manufacturers, exporters, distributors and traders.

    click here to find a list of Mometasone Furoate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

    Mometasone Furoate USDMF

    A Mometasone Furoate DMF (Drug Master File) is a document detailing the whole manufacturing process of Mometasone Furoate active pharmaceutical ingredient (API) in detail. Different forms of Mometasone Furoate DMFs exist exist since differing nations have different regulations, such as Mometasone Furoate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

    A Mometasone Furoate DMF submitted to regulatory agencies in the US is known as a USDMF. Mometasone Furoate USDMF includes data on Mometasone Furoate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Mometasone Furoate USDMF is kept confidential to protect the manufacturer’s intellectual property.

    click here to find a list of Mometasone Furoate suppliers with USDMF on PharmaCompass.

    Mometasone Furoate JDMF

    The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

    The Mometasone Furoate Drug Master File in Japan (Mometasone Furoate JDMF) empowers Mometasone Furoate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

    PMDA reviews the Mometasone Furoate JDMF during the approval evaluation for pharmaceutical products. At the time of Mometasone Furoate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

    click here to find a list of Mometasone Furoate suppliers with JDMF on PharmaCompass.

    Mometasone Furoate KDMF

    In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

    Pharmaceutical companies submit a Mometasone Furoate Drug Master File in Korea (Mometasone Furoate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Mometasone Furoate. The MFDS reviews the Mometasone Furoate KDMF as part of the drug registration process and uses the information provided in the Mometasone Furoate KDMF to evaluate the safety and efficacy of the drug.

    After submitting a Mometasone Furoate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Mometasone Furoate API can apply through the Korea Drug Master File (KDMF).

    click here to find a list of Mometasone Furoate suppliers with KDMF on PharmaCompass.

    Mometasone Furoate CEP

    A Mometasone Furoate CEP of the European Pharmacopoeia monograph is often referred to as a Mometasone Furoate Certificate of Suitability (COS). The purpose of a Mometasone Furoate CEP is to show that the European Pharmacopoeia monograph adequately controls the purity of Mometasone Furoate EP produced by a given manufacturer. Suppliers of raw materials can prove the suitability of Mometasone Furoate to their clients by showing that a Mometasone Furoate CEP has been issued for it. The manufacturer submits a Mometasone Furoate CEP (COS) as part of the market authorization procedure, and it takes on the role of a Mometasone Furoate CEP holder for the record. Additionally, the data presented in the Mometasone Furoate CEP (COS) is managed confidentially and offers a centralized system acknowledged by numerous nations, exactly like the Mometasone Furoate DMF.

    A Mometasone Furoate CEP (COS) is recognised by all 36 nations that make up the European Pharmacopoeia Convention. Mometasone Furoate CEPs may be accepted in nations that are not members of the Ph. Eur. at the discretion of the authorities there.

    click here to find a list of Mometasone Furoate suppliers with CEP (COS) on PharmaCompass.

    Mometasone Furoate WC

    A Mometasone Furoate written confirmation (Mometasone Furoate WC) is an official document issued by a regulatory agency to a Mometasone Furoate manufacturer, verifying that the manufacturing facility of a Mometasone Furoate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Mometasone Furoate APIs or Mometasone Furoate finished pharmaceutical products to another nation, regulatory agencies frequently require a Mometasone Furoate WC (written confirmation) as part of the regulatory process.

    click here to find a list of Mometasone Furoate suppliers with Written Confirmation (WC) on PharmaCompass.

    Mometasone Furoate NDC

    National Drug Code is a comprehensive database maintained by the FDA that contains information on all drugs marketed in the US. This directory includes information about finished drug products, unfinished drug products, and compounded drug products, including those containing Mometasone Furoate as an active pharmaceutical ingredient (API).

    Finished drug products

    The FDA updates the NDC directory daily. The NDC numbers for Mometasone Furoate API and other APIs are published in this directory by the FDA.

    Unfinished drugs

    The NDC unfinished drugs database includes product listing information submitted for all unfinished drugs, such as active pharmaceutical ingredients (APIs), drugs intended for further processing and bulk drug substances for compounding.

    Pharmaceutical companies that manufacture Mometasone Furoate as an active pharmaceutical ingredient (API) must furnish the FDA with an updated record of all drugs that they produce, prepare, propagate, compound, or process for commercial distribution in the US at their facilities.

    Compounded drug products

    The NDC directory also contains data on finished compounded human drug products that contain Mometasone Furoate and are produced by outsourcing facilities. While these outsourcing facilities are not mandated to assign a Mometasone Furoate NDC to their finished compounded human drug products, they may choose to do so.

    click here to find a list of Mometasone Furoate suppliers with NDC on PharmaCompass.

    Mometasone Furoate GMP

    Mometasone Furoate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

    GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

    PharmaCompass offers a list of Mometasone Furoate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mometasone Furoate GMP manufacturer or Mometasone Furoate GMP API supplier for your needs.

    Mometasone Furoate CoA

    A Mometasone Furoate CoA (Certificate of Analysis) is a formal document that attests to Mometasone Furoate's compliance with Mometasone Furoate specifications and serves as a tool for batch-level quality control.

    Mometasone Furoate CoA mostly includes findings from lab analyses of a specific batch. For each Mometasone Furoate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

    Mometasone Furoate may be tested according to a variety of international standards, such as European Pharmacopoeia (Mometasone Furoate EP), Mometasone Furoate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mometasone Furoate USP).

    Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
    For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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