Find Monomethyl Auristatin F manufacturers, exporters & distributors on PharmaCompass

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Chemistry

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Also known as: 745017-94-1, Monomethylauristatin f, Monomethyl auristatin f, (2s)-2-[[(2r,3r)-3-methoxy-3-[(2s)-1-[(3r,4s,5s)-3-methoxy-5-methyl-4-[methyl-[(2s)-3-methyl-2-[[(2s)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid, 1z1ai9iw5l, Monomethylauristatinf
Molecular Formula
C39H65N5O8
Molecular Weight
732.0  g/mol
InChI Key
MFRNYXJJRJQHNW-DEMKXPNLSA-N
FDA UNII
1Z1AI9IW5L

Monomethyl Auristatin F
1 2D Structure

Monomethyl Auristatin F

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-2-[[(2R,3R)-3-methoxy-3-[(2S)-1-[(3R,4S,5S)-3-methoxy-5-methyl-4-[methyl-[(2S)-3-methyl-2-[[(2S)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic acid
2.1.2 InChI
InChI=1S/C39H65N5O8/c1-12-25(6)34(43(9)38(48)33(24(4)5)42-37(47)32(40-8)23(2)3)30(51-10)22-31(45)44-20-16-19-29(44)35(52-11)26(7)36(46)41-28(39(49)50)21-27-17-14-13-15-18-27/h13-15,17-18,23-26,28-30,32-35,40H,12,16,19-22H2,1-11H3,(H,41,46)(H,42,47)(H,49,50)/t25-,26+,28-,29-,30+,32-,33-,34-,35+/m0/s1
2.1.3 InChI Key
MFRNYXJJRJQHNW-DEMKXPNLSA-N
2.1.4 Canonical SMILES
CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC
2.1.5 Isomeric SMILES
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC
2.2 Other Identifiers
2.2.1 UNII
1Z1AI9IW5L
2.3 Synonyms
2.3.1 MeSH Synonyms

1. Mmaf Peptide

2. Monomethyl Auristatin F

3. Monomethylauristatin F

2.3.2 Depositor-Supplied Synonyms

1. 745017-94-1

2. Monomethylauristatin F

3. Monomethyl Auristatin F

4. (2s)-2-[[(2r,3r)-3-methoxy-3-[(2s)-1-[(3r,4s,5s)-3-methoxy-5-methyl-4-[methyl-[(2s)-3-methyl-2-[[(2s)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic Acid

5. 1z1ai9iw5l

6. Monomethylauristatinf

7. (2~{s})-2-[[(2~{r},3~{r})-3-methoxy-3-[(2~{s})-1-[(3~{r},4~{s},5~{s})-3-methoxy-5-methyl-4-[methyl-[(2~{s})-3-methyl-2-[[(2~{s})-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methyl-propanoyl]amino]-3-phenyl-propanoic Acid

8. Schembl3208014

9. Chembl3359822

10. Monomethyl Auristatin F (mmaf)

11. Dtxsid601031563

12. (2s)-2-[[(2r,3r)-3-methoxy-3-[(2s)-1-[(3r,5s)-3-methoxy-5-methyl-4-[methyl-[(2s)-3-methyl-2-[[(2s)-3-methyl-2-(methylamino)butanoyl]amino]butanoyl]amino]heptanoyl]pyrrolidin-2-yl]-2-methylpropanoyl]amino]-3-phenylpropanoic Acid

13. Amy30768

14. Ex-a1046

15. Mfcd25976742

16. Zinc167866935

17. Monomethylauristatin Phenylalanine

18. Ac-30596

19. Bp-22316

20. Hy-15579

21. Db-094829

22. (s)-2-((2r,3r)-3-((s)-1-((3r,4s,5s)-4-((s)-n,3-dimethyl-2-((s)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic Acid

23. L-phenylalanine, N-methyl-l-valyl-l-valyl-(3r,4s,5s)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(.alpha.r,.beta.r,2s)-.beta.-methoxy-.alpha.-methyl-2-pyrrolidinepropanoyl-

2.4 Create Date
2006-10-25
3 Chemical and Physical Properties
Molecular Weight 732.0 g/mol
Molecular Formula C39H65N5O8
XLogP32.1
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count9
Rotatable Bond Count21
Exact Mass731.48331405 g/mol
Monoisotopic Mass731.48331405 g/mol
Topological Polar Surface Area167 Ų
Heavy Atom Count52
Formal Charge0
Complexity1160
Isotope Atom Count0
Defined Atom Stereocenter Count9
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

Monomethyl Auristatin F Manufacturers

A Monomethyl Auristatin F manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Monomethyl Auristatin F, including repackagers and relabelers. The FDA regulates Monomethyl Auristatin F manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Monomethyl Auristatin F API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Monomethyl Auristatin F manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Monomethyl Auristatin F Suppliers

A Monomethyl Auristatin F supplier is an individual or a company that provides Monomethyl Auristatin F active pharmaceutical ingredient (API) or Monomethyl Auristatin F finished formulations upon request. The Monomethyl Auristatin F suppliers may include Monomethyl Auristatin F API manufacturers, exporters, distributors and traders.

click here to find a list of Monomethyl Auristatin F suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Monomethyl Auristatin F GMP

Monomethyl Auristatin F Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Monomethyl Auristatin F GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Monomethyl Auristatin F GMP manufacturer or Monomethyl Auristatin F GMP API supplier for your needs.

Monomethyl Auristatin F CoA

A Monomethyl Auristatin F CoA (Certificate of Analysis) is a formal document that attests to Monomethyl Auristatin F's compliance with Monomethyl Auristatin F specifications and serves as a tool for batch-level quality control.

Monomethyl Auristatin F CoA mostly includes findings from lab analyses of a specific batch. For each Monomethyl Auristatin F CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Monomethyl Auristatin F may be tested according to a variety of international standards, such as European Pharmacopoeia (Monomethyl Auristatin F EP), Monomethyl Auristatin F JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Monomethyl Auristatin F USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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