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    Also known as: 52-26-6, Morphine hcl, Thebametten, Morphine chlorhydrate, Morphine chloride, Epimore
    Molecular Formula
    C17H20ClNO3
    Molecular Weight
    321.8  g/mol
    InChI Key
    XCKKIKBIPZJUET-VYKNHSEDSA-N
    FDA UNII
    J28GE0ROVX
    Morphine Hydrochloride
    The principal alkaloid in opium and the prototype opiate analgesic and narcotic. Morphine has widespread effects in the central nervous system and on smooth muscle.
    1 2D Structure

    Morphine Hydrochloride

    2 Identification
    2.1 Computed Descriptors
    2.1.1 IUPAC Name
    (4R,4aR,7S,7aR,12bS)-3-methyl-2,4,4a,7,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol;hydrochloride
    2.1.2 InChI
    InChI=1S/C17H19NO3.ClH/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18;/h2-5,10-11,13,16,19-20H,6-8H2,1H3;1H/t10-,11+,13-,16-,17-;/m0./s1
    2.1.3 InChI Key
    XCKKIKBIPZJUET-VYKNHSEDSA-N
    2.1.4 Canonical SMILES
    CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O.Cl
    2.1.5 Isomeric SMILES
    CN1CC[C@]23[C@@H]4[C@H]1CC5=C2C(=C(C=C5)O)O[C@H]3[C@H](C=C4)O.Cl
    2.2 Other Identifiers
    2.2.1 UNII
    J28GE0ROVX
    2.3 Synonyms
    2.3.1 MeSH Synonyms

    1. Chloride, Morphine

    2. Contin, Ms

    3. Duramorph

    4. Morphia

    5. Morphine

    6. Morphine Chloride

    7. Morphine Sulfate

    8. Morphine Sulfate (2:1), Anhydrous

    9. Morphine Sulfate (2:1), Pentahydrate

    10. Ms Contin

    11. Oramorph Sr

    12. Sdz 202 250

    13. Sdz 202-250

    14. Sdz 202250

    15. Sdz202 250

    16. Sdz202-250

    17. Sdz202250

    18. Sulfate, Morphine

    2.3.2 Depositor-Supplied Synonyms

    1. 52-26-6

    2. Morphine Hcl

    3. Thebametten

    4. Morphine Chlorhydrate

    5. Morphine Chloride

    6. Epimore

    7. Ampek

    8. (-)-morphine Hydrochloride

    9. Theba-intran

    10. Vendal

    11. Morphinum Muriaticum

    12. Morphinium Chloride

    13. J28ge0rovx

    14. Chebi:55340

    15. Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, Hydrochloride

    16. Morphine Hydrochloride Hydrate

    17. Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, Hydrochloride, (5-alpha,6-alpha)-

    18. (4r,4ar,7s,7ar,12bs)-3-methyl-2,4,4a,7,7a,13-hexahydro-1h-4,12-methanobenzofuro[3,2-e]isoquinoline-7,9-diol;hydrochloride

    19. Unii-j28ge0rovx

    20. Morphine-hcl

    21. Morphin-hcl

    22. Morphine Hydrochloride [usp:jan]

    23. Einecs 200-136-2

    24. Opso

    25. Morphini Hydrochloridum

    26. Morphine Hydro Chloride

    27. Morphiniumchloride

    28. Schembl40902

    29. (+/-)-morphine Hydrochloride

    30. Morphine Hydrochloric Acid Salt

    31. Chembl556578

    32. Dtxsid10110023

    33. Dtxsid501045894

    34. Morphine Hydrochloride [mi]

    35. Morphinum Muriaticum [hpus]

    36. Akos024458522

    37. Morphine Hydrochloride [mart.]

    38. Morphine Hydrochloride [who-dd]

    39. B5814

    40. Morphine Hydrochloride [ep Monograph]

    41. Q27124243

    42. 17-methyl-7,8-didehydro-4,5alpha-epoxymorphinan-3,6alpha-diol Hydrochloride

    43. 7,8-didehydro-4,5-epoxy-17-methyl-(5?,6?)-morphinan-3,6-diol Hydrochloride

    44. Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, (5alpha,6alpha)-, Hydrochloride

    45. Morphinan-3,6alpha-diol, 7,8-didehydro-4,5alpha-epoxy-17-methyl-, Hydrochloride (8ci)

    46. (5alpha,6alpha)-7,8-didehydro-4,5-epoxy-17-methyl-morphinan-3,6-diol, Hydrochloride (1:1)

    47. Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5.alpha.,6.alpha.)-, Hydrochloride (1:1)

    48. Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5alpha,6alpha)-, Hydrochloride (9ci)

    2.4 Create Date
    2005-06-01
    3 Chemical and Physical Properties
    Molecular Weight 321.8 g/mol
    Molecular Formula C17H20ClNO3
    Hydrogen Bond Donor Count3
    Hydrogen Bond Acceptor Count4
    Rotatable Bond Count0
    Exact Mass321.1131712 g/mol
    Monoisotopic Mass321.1131712 g/mol
    Topological Polar Surface Area52.9 Ų
    Heavy Atom Count22
    Formal Charge0
    Complexity494
    Isotope Atom Count0
    Defined Atom Stereocenter Count5
    Undefined Atom Stereocenter Count0
    Defined Bond Stereocenter Count0
    Undefined Bond Stereocenter Count0
    Covalently Bonded Unit Count2
    4 Pharmacology and Biochemistry
    4.1 MeSH Pharmacological Classification

    Analgesics, Opioid

    Compounds with activity like OPIATE ALKALOIDS, acting at OPIOID RECEPTORS. Properties include induction of ANALGESIA or NARCOSIS. (See all compounds classified as Analgesics, Opioid.)

    Narcotics

    Agents that induce NARCOSIS. Narcotics include agents that cause somnolence or induced sleep (STUPOR); natural or synthetic derivatives of OPIUM or MORPHINE or any substance that has such effects. They are potent inducers of ANALGESIA and OPIOID-RELATED DISORDERS. (See all compounds classified as Narcotics.)

    API Reference Price

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D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1643826600,"product":"APOMORPHINE HYDROCHLORIDE (QTY:1X0.5 GMS,PRICE: USD 36.83)(FOC)","address":"P.NO. 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D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,","city":"TURKAPALLY-V SHAMIRPET HYDERABAD,TE","supplier":"UNITED STATES PHARMACOPEIAL ","supplierCountry":"UNITED KINGDOM","foreign_port":"NA","customer":"UNITED STATES PHARMACOPEIA - INDIA PRIVATE LIMITED","customerCountry":"INDIA","quantity":"0.00","actualQuantity":"0.0005","unit":"KGS","unitRateFc":"1052000","totalValueFC":"610.6","currency":"USD","unitRateINR":"91537300","date":"03-Feb-2022","totalValueINR":"45768.65","totalValueInUsd":"610.6","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"7333943","productDescription":"API","marketType":"REGULATED MARKET","country":"UNITED KINGDOM","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"P.NO. D6 & D8, SY.NO. 234\/2,234\/3, ,235\/2 & 542\/2, IKP KNOWLEDGE PARK,"},{"dataSource":"API Import","activeIngredients":"","year":"2022","qtr":"Q1","strtotime":1648578600,"product":"APOMORPHINE HYDROCHLORIDE (TEST LIC- TL\/AZ\/22\/000721) FOR R& D PURPOSE NOT FOR SALE","address":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. VAISHNODE","city":"AHMEDABAD","supplier":"FRANCOPIA","supplierCountry":"FRANCE","foreign_port":"NA","customer":"ZYDUS LIFESCIENCES","customerCountry":"INDIA","quantity":"0.19","actualQuantity":"190","unit":"GMS","unitRateFc":"10","totalValueFC":"1917","currency":"USD","unitRateINR":"769","date":"30-Mar-2022","totalValueINR":"146110","totalValueInUsd":"1917","indian_port":"BOMBAY AIR","hs_no":"29339990","bill_no":"8071277","productDescription":"API","marketType":"REGULATED MARKET","country":"FRANCE","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"ZYDUS CORPORATE PARK, SCHEME NO 63, KHORAJ (GANDHINAGAR), NR. VAISHNODE"},{"dataSource":"API Import","activeIngredients":"","year":"2023","qtr":"Q1","strtotime":1680201000,"product":"101746 - APOMORPHINE HYDROCHLORIDE (BATCH: T230726-22-00499)(LAB TESTING ONLY) (FOC) (200 GRM)","address":"SANALI INFO PARK, 8-2-120\/113,ROAD NO.2, BANJARA HILLS","city":"HYDERABAD,TELANGANA","supplier":"PATHEON","supplierCountry":"ITALY","foreign_port":"NA","customer":"NEULAND LABORATORIES","customerCountry":"INDIA","quantity":"0.20","actualQuantity":"0.2","unit":"KGS","unitRateFc":"6957","totalValueFC":"2083.9","currency":"GBP","unitRateINR":"856992","date":"31-Mar-2023","totalValueINR":"171398.4","totalValueInUsd":"2083.9","indian_port":"HYDERABAD AIR","hs_no":"29339990","bill_no":"5313206","productDescription":"API","marketType":"REGULATED MARKET","country":"ITALY","selfForZScoreResived":"Pharma Grade","supplierPort":"NA","supplierAddress":"","customerAddress":"SANALI INFO PARK, 8-2-120\/113,ROAD NO.2, BANJARA HILLS"}]
    01-Mar-2021
    30-Jan-2024
    KGS
    overview
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    Average Price (USD/KGS)

    Number of Transactions

    Total Quantity (KGS)

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    Quantity (KGS) & Unit rate (USD/KGS) over time

    API Imports and Exports

    Importing Country Total Quantity
    (KGS)    		 Average Price
    (USD/KGS)    		 Number of Transactions

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