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Chemistry

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Also known as: 112885-42-4, Gasmotin, As-4370, Mosapride (citrate), Tak-370, Rimopride citrate
Molecular Formula
C27H33ClFN3O10
Molecular Weight
614.0  g/mol
InChI Key
HUZTYZBFZKRPFG-UHFFFAOYSA-N
FDA UNII
MF497J489P

Mosapride Citrate
1 2D Structure

Mosapride Citrate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic acid
2.1.2 InChI
InChI=1S/C21H25ClFN3O3.C6H8O7/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)
2.1.3 InChI Key
HUZTYZBFZKRPFG-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCOC1=CC(=C(C=C1C(=O)NCC2CN(CCO2)CC3=CC=C(C=C3)F)Cl)N.C(C(=O)O)C(CC(=O)O)(C(=O)O)O
2.2 Other Identifiers
2.2.1 UNII
MF497J489P
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 4-amino-5-chloro-2-ethoxy-n-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide

2. As 4370

3. As-4370

4. Mosapride

5. Mosapride Ui05msp015ct

2.3.2 Depositor-Supplied Synonyms

1. 112885-42-4

2. Gasmotin

3. As-4370

4. Mosapride (citrate)

5. Tak-370

6. Rimopride Citrate

7. 4-amino-5-chloro-2-ethoxy-n-((4-(4-fluorobenzyl)morpholin-2-yl)methyl)benzamide 2-hydroxypropane-1,2,3-tricarboxylate

8. Gasmot

9. Mf497j489p

10. Dsstox_cid_26207

11. Dsstox_rid_81436

12. Dsstox_gsid_46207

13. 4-amino-5-chloro-2-ethoxy-n-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide Citrate

14. Cas-112885-42-4

15. C21h25clfn3o3.c6h8o7

16. Unii-mf497j489p

17. Gasmotin Citrate

18. Tak-370 Citrate

19. As-4370 Citrate

20. Mosapride Citrate- Bio-x

21. (+-)-4-amino-5-chloro-2-ethoxy-n-((4-(4-fluorobenzyl)-2-morpholinyl)methyl)benzamide Citrate

22. Mls006011997

23. Schembl258620

24. Mosapride Citrate [mi]

25. Tak370

26. Chembl1733174

27. Dtxsid7046207

28. Hy-b0189a

29. Amy8852

30. Tak 370

31. Hms2051p15

32. Hms2234k07

33. Hms3369k19

34. Hms3393p15

35. Hms3651o09

36. Hms3884e13

37. Mosapride Citrate [who-dd]

38. Bcp08880

39. Tox21_111874

40. Mfcd01666680

41. Mosapride Citrate - Adooq Bioscience

42. S1385

43. Akos015895400

44. Tox21_111874_1

45. Ccg-100966

46. Ccg-270241

47. Nc00216

48. Ncgc00160527-03

49. As-13388

50. Benzamide, 4-amino-5-chloro-2-ethoxy-n-((4-((4-fluorophenyl)methyl)-2-morpholinyl)methyl)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)

51. Bm164611

52. Sw197596-2

53. 85m424

54. D70344

55. A921736

56. Q27283985

57. (+/-)-4-amino-5-chloro-2-ethoxy-n-((4-(p-fluorobenzyl)-2-morpholinyl)methyl)benzamide Citrate

58. 4-amino-5-chloro-2-ethoxy-n-[[4-[(4 -fluorophenyl)methyl]-2-morpholinyl]methyl]benzami De Citrate

59. 4-amino-5-chloro-2-ethoxy-n-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]benzamide Citrate

60. 4-amino-5-chloro-2-ethoxy-n-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide;2-hydroxypropane-1,2,3-tricarboxylic Acid.

61. Tak-370 Citrate; As-4370 Citrat;tak370 Citrate; As4370 Citrat;tak 370 Citrate; As 4370 Citrat

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 614.0 g/mol
Molecular Formula C27H33ClFN3O10
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count13
Rotatable Bond Count12
Exact Mass613.1838501 g/mol
Monoisotopic Mass613.1838501 g/mol
Topological Polar Surface Area209 Ų
Heavy Atom Count42
Formal Charge0
Complexity749
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count2
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Serotonin Receptor Agonists

Endogenous compounds and drugs that bind to and activate SEROTONIN RECEPTORS. Many serotonin receptor agonists are used as ANTIDEPRESSANTS; ANXIOLYTICS; and in the treatment of MIGRAINE DISORDERS. (See all compounds classified as Serotonin Receptor Agonists.)


Gastrointestinal Agents

Drugs used for their effects on the gastrointestinal system, as to control gastric acidity, regulate gastrointestinal motility and water flow, and improve digestion. (See all compounds classified as Gastrointestinal Agents.)


API Reference Price

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04-Jan-2021
30-Nov-2024
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Looking for 112885-42-4 / Mosapride Citrate API manufacturers, exporters & distributors?

Mosapride Citrate manufacturers, exporters & distributors 1

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PharmaCompass offers a list of Mosapride Citrate API manufacturers, exporters & distributors, which can be sorted by GMP, USDMF, JDMF, KDMF, CEP (COS), WC, Price,and more, enabling you to easily find the right Mosapride Citrate manufacturer or Mosapride Citrate supplier for your needs.

Send us enquiries for free, and we will assist you in establishing a direct connection with your preferred Mosapride Citrate manufacturer or Mosapride Citrate supplier.

PharmaCompass also assists you with knowing the Mosapride Citrate API Price utilized in the formulation of products. Mosapride Citrate API Price is not always fixed or binding as the Mosapride Citrate Price is obtained through a variety of data sources. The Mosapride Citrate Price can also vary due to multiple factors, including market conditions, regulatory modifications, or negotiated pricing deals.

API | Excipient name

Mosapride Citrate

Synonyms

112885-42-4, Gasmotin, As-4370, Mosapride (citrate), Tak-370, Rimopride citrate

Cas Number

112885-42-4

Unique Ingredient Identifier (UNII)

MF497J489P

Mosapride Citrate Manufacturers

A Mosapride Citrate manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Mosapride Citrate, including repackagers and relabelers. The FDA regulates Mosapride Citrate manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Mosapride Citrate API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Mosapride Citrate manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Mosapride Citrate Suppliers

A Mosapride Citrate supplier is an individual or a company that provides Mosapride Citrate active pharmaceutical ingredient (API) or Mosapride Citrate finished formulations upon request. The Mosapride Citrate suppliers may include Mosapride Citrate API manufacturers, exporters, distributors and traders.

click here to find a list of Mosapride Citrate suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Mosapride Citrate USDMF

A Mosapride Citrate DMF (Drug Master File) is a document detailing the whole manufacturing process of Mosapride Citrate active pharmaceutical ingredient (API) in detail. Different forms of Mosapride Citrate DMFs exist exist since differing nations have different regulations, such as Mosapride Citrate USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Mosapride Citrate DMF submitted to regulatory agencies in the US is known as a USDMF. Mosapride Citrate USDMF includes data on Mosapride Citrate's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Mosapride Citrate USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Mosapride Citrate suppliers with USDMF on PharmaCompass.

Mosapride Citrate JDMF

The Pharmaceuticals and Medical Devices Agency (PMDA) established the Japan Drug Master File (JDMF), also known as the Master File (MF), to permit Japanese and foreign manufacturers of drug substances, intermediates, excipients, raw materials, and packaging materials (‘Products’) to voluntarily register confidential information about the production and management of their products in Japan.

The Mosapride Citrate Drug Master File in Japan (Mosapride Citrate JDMF) empowers Mosapride Citrate API manufacturers to present comprehensive information (e.g., production methods, data, etc.) to the review authority, i.e., PMDA (Pharmaceuticals & Medical Devices Agency).

PMDA reviews the Mosapride Citrate JDMF during the approval evaluation for pharmaceutical products. At the time of Mosapride Citrate JDMF registration, PMDA checks if the format is accurate, if the necessary items have been included (application), and if data has been attached.

click here to find a list of Mosapride Citrate suppliers with JDMF on PharmaCompass.

Mosapride Citrate KDMF

In Korea, the Ministry of Food and Drug Safety (MFDS) is in charge of regulating pharmaceutical products and services.

Pharmaceutical companies submit a Mosapride Citrate Drug Master File in Korea (Mosapride Citrate KDMF) to the MFDS, which includes comprehensive information about the production, processing, facilities, materials, packaging, and testing of Mosapride Citrate. The MFDS reviews the Mosapride Citrate KDMF as part of the drug registration process and uses the information provided in the Mosapride Citrate KDMF to evaluate the safety and efficacy of the drug.

After submitting a Mosapride Citrate KDMF to the MFDS, the registered manufacturer can provide importers or distributors with the registration number without revealing confidential information to Korean business partners. Applicants seeking to register their Mosapride Citrate API can apply through the Korea Drug Master File (KDMF).

click here to find a list of Mosapride Citrate suppliers with KDMF on PharmaCompass.

Mosapride Citrate WC

A Mosapride Citrate written confirmation (Mosapride Citrate WC) is an official document issued by a regulatory agency to a Mosapride Citrate manufacturer, verifying that the manufacturing facility of a Mosapride Citrate active pharmaceutical ingredient (API) adheres to the Good Manufacturing Practices (GMP) regulations of the importing country. When exporting Mosapride Citrate APIs or Mosapride Citrate finished pharmaceutical products to another nation, regulatory agencies frequently require a Mosapride Citrate WC (written confirmation) as part of the regulatory process.

click here to find a list of Mosapride Citrate suppliers with Written Confirmation (WC) on PharmaCompass.

Mosapride Citrate GMP

Mosapride Citrate Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Mosapride Citrate GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Mosapride Citrate GMP manufacturer or Mosapride Citrate GMP API supplier for your needs.

Mosapride Citrate CoA

A Mosapride Citrate CoA (Certificate of Analysis) is a formal document that attests to Mosapride Citrate's compliance with Mosapride Citrate specifications and serves as a tool for batch-level quality control.

Mosapride Citrate CoA mostly includes findings from lab analyses of a specific batch. For each Mosapride Citrate CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Mosapride Citrate may be tested according to a variety of international standards, such as European Pharmacopoeia (Mosapride Citrate EP), Mosapride Citrate JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Mosapride Citrate USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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