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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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FDF

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Europe

Europe

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Canada

Canada

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Australia

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South Africa

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Chemistry

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Also known as: Moxam, Latamoxef sodium, Shiomarin, Latamoxef disodium, Moxalactam sodium, Disodium latamoxef
Molecular Formula
C20H18N6Na2O9S
Molecular Weight
564.4  g/mol
InChI Key
GRIXGZQULWMCLU-HUTAOCTPSA-L
FDA UNII
5APW73W3QZ

Moxalactam
Broad- spectrum beta-lactam antibiotic similar in structure to the CEPHALOSPORINS except for the substitution of an oxaazabicyclo moiety for the thiaazabicyclo moiety of certain CEPHALOSPORINS. It has been proposed especially for the meningitides because it passes the blood-brain barrier and for anaerobic infections.
1 2D Structure

Moxalactam

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
disodium;(6R,7R)-7-[[2-carboxylato-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
2.1.2 InChI
InChI=1S/C20H20N6O9S.2Na/c1-25-19(22-23-24-25)36-8-10-7-35-18-20(34-2,17(33)26(18)13(10)16(31)32)21-14(28)12(15(29)30)9-3-5-11(27)6-4-9;;/h3-6,12,18,27H,7-8H2,1-2H3,(H,21,28)(H,29,30)(H,31,32);;/q;2*+1/p-2/t12?,18-,20+;;/m1../s1
2.1.3 InChI Key
GRIXGZQULWMCLU-HUTAOCTPSA-L
2.1.4 Canonical SMILES
CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)(NC(=O)C(C4=CC=C(C=C4)O)C(=O)[O-])OC)OC2)C(=O)[O-].[Na+].[Na+]
2.1.5 Isomeric SMILES
CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)C(C4=CC=C(C=C4)O)C(=O)[O-])OC)OC2)C(=O)[O-].[Na+].[Na+]
2.2 Other Identifiers
2.2.1 UNII
5APW73W3QZ
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 1 Oxacephalosporin

2. 1-oxacephalosporin

3. 6059 S

4. 6059-s

5. 6059s

6. Disodium Latamoxef

7. Disodium Moxalactam

8. Disodium, Moxalactam

9. Festamoxin

10. Lamoxactam

11. Latamoxef

12. Latamoxef, Disodium

13. Lilly 127935

14. Ly 127935

15. Ly-127935

16. Ly127935

17. Moxalactam

18. Moxalactam, Disodium

19. S 6059

20. S-6059

21. S6059

22. Shiomarin

2.3.2 Depositor-Supplied Synonyms

1. Moxam

2. Latamoxef Sodium

3. Shiomarin

4. Latamoxef Disodium

5. Moxalactam Sodium

6. Disodium Latamoxef

7. 64953-12-4

8. Moxalactam Disodium Salt

9. Latamoxefum Dinatricum

10. Ly-127935

11. Moxalactam Disodium [usan]

12. 5apw73w3qz

13. Ly127935

14. Nsc-757107

15. 6059-s

16. Moxalactam Disodium (usan)

17. Dsstox_cid_25595

18. Dsstox_rid_80988

19. Dsstox_gsid_45595

20. N-((6r,7r)-2-carboxy-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-oxa-1-azabicyclo(4.2.0)oct-2-en-7-yl)-2-(p-hydroxyphenyl)malonamic Acid Disodium Salt

21. Shionogi 6059s

22. Antibiotic 6059-s

23. Moxalactam Sodium Salt

24. 5-oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic Acid, 7-((carboxy(4-hydroxyphenyl)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-, Disodium Salt

25. Unii-5apw73w3qz

26. Festamoxinly

27. Ly 127935

28. Moxalactam Disodium [usan:usp]

29. Prestwick_33

30. Shiomarin (tn)

31. Ncgc00017130-01

32. Einecs 265-288-4

33. Cas-64953-12-4

34. Antibiotic 6059s

35. Moxam (tn)

36. 6059s

37. Latamoxef Sodium (jp17)

38. Schembl49015

39. Spectrum1500418

40. Latamoxef Sodium [jan]

41. Chembl1200357

42. Dtxsid0045595

43. Hms502n11

44. Latamoxef Sodium [who-dd]

45. Hms1570d19

46. Hms1920p05

47. Hms2091h04

48. Latamoxef Disodium [mart.]

49. Moxalactam Disodium [vandf]

50. Tox21_110793

51. Ccg-40101

52. Mfcd03427565

53. Moxalactam Disodium Salt [mi]

54. Akos025310623

55. Tox21_110793_1

56. Nsc 757107

57. Moxalactam Disodium [orange Book]

58. Ncgc00178851-03

59. 6059 S

60. D02198

61. S-6059

62. A899855

63. Q27261755

64. (6r,7r)-7-[[(2r)-2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1h-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid, Disodium Salt

65. (6r,7r)-7-[[2-carboxy(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[[(1-methyl-1h-tetrazol-5-yl)thio]methyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid Disodium Salt

66. Disodium 7-((carboxylato(4-hydroxyphenyl)acetyl)amino)-7-methoxy-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-oxo-5-oxa-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 564.4 g/mol
Molecular Formula C20H18N6Na2O9S
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count13
Rotatable Bond Count7
Exact Mass564.06513591 g/mol
Monoisotopic Mass564.06513591 g/mol
Topological Polar Surface Area237 Ų
Heavy Atom Count38
Formal Charge0
Complexity947
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count3
4 Pharmacology and Biochemistry
4.1 MeSH Pharmacological Classification

Anti-Bacterial Agents

Substances that inhibit the growth or reproduction of BACTERIA. (See all compounds classified as Anti-Bacterial Agents.)


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ABOUT THIS PAGE

Moxalactam Manufacturers

A Moxalactam manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Moxalactam, including repackagers and relabelers. The FDA regulates Moxalactam manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Moxalactam API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Moxalactam manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Moxalactam Suppliers

A Moxalactam supplier is an individual or a company that provides Moxalactam active pharmaceutical ingredient (API) or Moxalactam finished formulations upon request. The Moxalactam suppliers may include Moxalactam API manufacturers, exporters, distributors and traders.

click here to find a list of Moxalactam suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Moxalactam USDMF

A Moxalactam DMF (Drug Master File) is a document detailing the whole manufacturing process of Moxalactam active pharmaceutical ingredient (API) in detail. Different forms of Moxalactam DMFs exist exist since differing nations have different regulations, such as Moxalactam USDMF, ASMF (EDMF), JDMF, CDMF, etc.

A Moxalactam DMF submitted to regulatory agencies in the US is known as a USDMF. Moxalactam USDMF includes data on Moxalactam's chemical properties, information on the facilities and procedures used, and details about packaging and storage. The Moxalactam USDMF is kept confidential to protect the manufacturer’s intellectual property.

click here to find a list of Moxalactam suppliers with USDMF on PharmaCompass.

Moxalactam GMP

Moxalactam Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Moxalactam GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Moxalactam GMP manufacturer or Moxalactam GMP API supplier for your needs.

Moxalactam CoA

A Moxalactam CoA (Certificate of Analysis) is a formal document that attests to Moxalactam's compliance with Moxalactam specifications and serves as a tool for batch-level quality control.

Moxalactam CoA mostly includes findings from lab analyses of a specific batch. For each Moxalactam CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Moxalactam may be tested according to a variety of international standards, such as European Pharmacopoeia (Moxalactam EP), Moxalactam JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Moxalactam USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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