Find MRTX1133 manufacturers, exporters & distributors on PharmaCompass

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Synopsis

Synopsis

ACTIVE PHARMA INGREDIENTS

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USDMF

US DMFs Filed

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CEP/COS

CEP/COS Certifications

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JDMF

JDMFs Filed

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EU WC

EU WC

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KDMF

KDMF

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NDC API

NDC API

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VMF

NDC API

API REF. PRICE (USD/KG)

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$ 0

MARKET PLACE

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API

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FDF

0INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

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FDF Dossiers

FDF Dossiers

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FDA Orange Book

FDA (Orange Book)

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Europe

Europe

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Canada

Canada

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Australia

Australia

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South Africa

South Africa

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Listed Dossiers

Listed Dossiers

FDF Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

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EDQM

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USP

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JP

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Others

PATENTS & EXCLUSIVITIES

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US Patents

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US Exclusivities

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Health Canada Patents

DIGITAL CONTENT

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Data Compilation #PharmaFlow

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Stock Recap #PipelineProspector

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Weekly News Recap #Phispers

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News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid

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Annual Reports

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Finished Drug Prices

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Chemistry

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Also known as: Mrtx1133, 2621928-55-8, Chembl4858364, Schembl23053403, Ex-a5363, Bdbm50579601
Molecular Formula
C33H31F3N6O2
Molecular Weight
600.6  g/mol
InChI Key
SCLLZBIBSFTLIN-IFMUVJFISA-N

MRTX1133
1 2D Structure

MRTX1133

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
4-[4-(3,8-diazabicyclo[3.2.1]octan-3-yl)-8-fluoro-2-[[(2R,8S)-2-fluoro-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]pyrido[4,3-d]pyrimidin-7-yl]-5-ethynyl-6-fluoronaphthalen-2-ol
2.1.2 InChI
InChI=1S/C33H31F3N6O2/c1-2-23-26(35)7-4-18-10-22(43)11-24(27(18)23)29-28(36)30-25(13-37-29)31(41-15-20-5-6-21(16-41)38-20)40-32(39-30)44-17-33-8-3-9-42(33)14-19(34)12-33/h1,4,7,10-11,13,19-21,38,43H,3,5-6,8-9,12,14-17H2/t19-,20?,21?,33+/m1/s1
2.1.3 InChI Key
SCLLZBIBSFTLIN-IFMUVJFISA-N
2.1.4 Canonical SMILES
C#CC1=C(C=CC2=CC(=CC(=C21)C3=NC=C4C(=C3F)N=C(N=C4N5CC6CCC(C5)N6)OCC78CCCN7CC(C8)F)O)F
2.1.5 Isomeric SMILES
C#CC1=C(C=CC2=CC(=CC(=C21)C3=NC=C4C(=C3F)N=C(N=C4N5CC6CCC(C5)N6)OC[C@@]78CCCN7C[C@@H](C8)F)O)F
2.2 Synonyms
2.2.1 MeSH Synonyms

1. Krasg12d Inhibitor Mrtx1133

2. Mrtx1133

2.2.2 Depositor-Supplied Synonyms

1. Mrtx1133

2. 2621928-55-8

3. Chembl4858364

4. Schembl23053403

5. Ex-a5363

6. Bdbm50579601

7. Nsc836407

8. Nsc-836407

9. Ac-36979

10. Hy-134813

11. Cs-0159110

12. F78346

13. 4-(4-(3,8-diazabicyclo[3.2.1]octan-3-yl)-8-fluoro-2-(((2r,7as)-2-fluorohexahydro-1h-pyrrolizin-7a-yl)methoxy)pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol

14. 4-(4-(3,8-diazabicyclo[3.2.1]octan-3-yl)-8-fluoro-2-(((2r,7as)-2-fluorotetrahydro-1h-pyrrolizin-7a(5h)-yl)methoxy)pyrido[4,3-d]pyrimidin-7-yl)-5-ethynyl-6-fluoronaphthalen-2-ol

2.3 Create Date
2021-08-21
3 Chemical and Physical Properties
Molecular Weight 600.6 g/mol
Molecular Formula C33H31F3N6O2
XLogP35.2
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count11
Rotatable Bond Count6
Exact Mass600.24605874 g/mol
Monoisotopic Mass600.24605874 g/mol
Topological Polar Surface Area86.6 Ų
Heavy Atom Count44
Formal Charge0
Complexity1100
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count2
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

ABOUT THIS PAGE

MRTX1133 Manufacturers

A MRTX1133 manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of MRTX1133, including repackagers and relabelers. The FDA regulates MRTX1133 manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. MRTX1133 API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of MRTX1133 manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

MRTX1133 Suppliers

A MRTX1133 supplier is an individual or a company that provides MRTX1133 active pharmaceutical ingredient (API) or MRTX1133 finished formulations upon request. The MRTX1133 suppliers may include MRTX1133 API manufacturers, exporters, distributors and traders.

click here to find a list of MRTX1133 suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

MRTX1133 GMP

MRTX1133 Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of MRTX1133 GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right MRTX1133 GMP manufacturer or MRTX1133 GMP API supplier for your needs.

MRTX1133 CoA

A MRTX1133 CoA (Certificate of Analysis) is a formal document that attests to MRTX1133's compliance with MRTX1133 specifications and serves as a tool for batch-level quality control.

MRTX1133 CoA mostly includes findings from lab analyses of a specific batch. For each MRTX1133 CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

MRTX1133 may be tested according to a variety of international standards, such as European Pharmacopoeia (MRTX1133 EP), MRTX1133 JP (Japanese Pharmacopeia) and the US Pharmacopoeia (MRTX1133 USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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