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Chemistry

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Also known as: Butyl 2-cyanoacrylate, 6606-65-1, N-butyl cyanoacrylate, Butyl cyanoacrylate, Histoacryl, N-butyl-2-cyanoacrylate
Molecular Formula
C8H11NO2
Molecular Weight
153.18  g/mol
InChI Key
JJJFUHOGVZWXNQ-UHFFFAOYSA-N
FDA UNII
F8CEP82QNP

n-Butyl Cyanoacrylate
A tissue adhesive that is applied as a monomer to moist tissue and polymerizes to form a bond. It is slowly biodegradable and used in all kinds of surgery, including dental.
1 2D Structure

n-Butyl Cyanoacrylate

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
butyl 2-cyanoprop-2-enoate
2.1.2 InChI
InChI=1S/C8H11NO2/c1-3-4-5-11-8(10)7(2)6-9/h2-5H2,1H3
2.1.3 InChI Key
JJJFUHOGVZWXNQ-UHFFFAOYSA-N
2.1.4 Canonical SMILES
CCCCOC(=O)C(=C)C#N
2.2 Other Identifiers
2.2.1 UNII
F8CEP82QNP
2.3 Synonyms
2.3.1 MeSH Synonyms

1. 2 Cyanobutylacrylate

2. 2-cyanobutylacrylate

3. 2-cyanobutylacrylates

4. Butyl 2 Cyanacrylate

5. Butyl 2-cyanacrylate

6. Butyl 2-cyanacrylates

7. Butylcyanoacrylate

8. Butylcyanoacrylates

9. Chirurcoll

10. Cyanoacrylate, Polybutyl

11. Cyanoacrylate, Polyisobutyl

12. Cyanoacrylates, Polybutyl

13. Cyanoacrylates, Polyisobutyl

14. Enbucrilate, Homopolymer

15. Enbucrilates

16. Enbucrilates, Homopolymer

17. Enbucrylate

18. Enbucrylates

19. Fimomed

20. Histacryl

21. Histacryls

22. Histoacryl

23. Histoacryl Blue

24. Histoacryl N Blau

25. Histoacryl N-blau

26. Histoacryls

27. Kanokonlit

28. Ligament-fimomed

29. N Butyl 2 Cyanoacrylate

30. N Butyl Cyanoacrylate

31. N-butyl-2-cyanoacrylate

32. N-butyl-2-cyanoacrylates

33. N-butyl-cyanoacrylate

34. N-butyl-cyanoacrylates

35. Nbca Compound

36. Nbca Compounds

37. Poly(isobutyl Cyanoacrylate)

38. Polybutyl Cyanoacrylate

39. Polybutyl Cyanoacrylates

40. Polyisobutyl Cyanoacrylate

41. Polyisobutyl Cyanoacrylates

42. Polyisobutylcyanoacrylate

43. Polyisobutylcyanoacrylates

2.3.2 Depositor-Supplied Synonyms

1. Butyl 2-cyanoacrylate

2. 6606-65-1

3. N-butyl Cyanoacrylate

4. Butyl Cyanoacrylate

5. Histoacryl

6. N-butyl-2-cyanoacrylate

7. Butyl 2-cyanoprop-2-enoate

8. 2-propenoic Acid, 2-cyano-, Butyl Ester

9. Glustitch

10. Medibond

11. Medicryl

12. Periacryl

13. Vetbond

14. F8cep82qnp

15. 2-cyano-2-propenoic Acid Butyl Ester

16. Enbucrilate (inn)

17. 25154-80-7

18. Enbucrilate [inn]

19. Enbucrilato

20. Enbucrilatum

21. Enbucrilate [inn:ban]

22. Unii-f8cep82qnp

23. Enbucrilatum [inn-latin]

24. Enbucrilato [inn-spanish]

25. Butyl 2-cyano-2-propenoate

26. Histoacryl (tn)

27. Einecs 229-552-2

28. Ec 229-552-2

29. Enbucrilate [mart.]

30. Schembl24796

31. Enbucrilate [who-dd]

32. 95% (stabilized With Tbc)

33. Cyanoacrylic Acid N-butyl Ester

34. Chembl2104251

35. Dtxsid5064417

36. Chebi:134778

37. Glxc-10897

38. N-butyl Cyanoacrylate [mi]

39. Mfcd00134196

40. Akos006272156

41. Db12358

42. Ds-7460

43. Hy-107346

44. A8931

45. Cs-0028189

46. Ns00003729

47. D07893

48. A1-01952

49. Q5003173

50. Inchi=1/c8h11no2/c1-3-4-5-11-8(10)7(2)6-9/h2-5h2,1h

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 153.18 g/mol
Molecular Formula C8H11NO2
XLogP32.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count3
Rotatable Bond Count5
Exact Mass g/mol
Monoisotopic Mass g/mol
Topological Polar Surface Area50.1
Heavy Atom Count11
Formal Charge0
Complexity199
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1
4 Drug and Medication Information
4.1 Minimum/Potential Fatal Human Dose

211 to 300 milligrams for an adult human (cyanide salts). (T86)


5 Pharmacology and Biochemistry
5.1 Metabolism/Metabolites

Organic nitriles are converted into cyanide ions through the action of cytochrome P450 enzymes in the liver. Cyanide is rapidly absorbed and distributed throughout the body. Cyanide is mainly metabolized into thiocyanate by either rhodanese or 3-mercaptopyruvate sulfur transferase. Cyanide metabolites are excreted in the urine. (L96)


API SUPPLIERS

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01

Rusan Pharma

India

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

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Antibody Engineering
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothRusan Pharma: Over 30 years of specializing in the treatment of Addiction and Pain Management.

Flag India
Digital Content Digital Content
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
Rusan Pharma

02

FandaChem

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering
Not Confirmed
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FandaChem

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

arrow
Antibody Engineering
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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03

J&H CHEM

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

Antibody Engineering
Not Confirmed
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J&H CHEM

China

USDMF, CEP/COS, JDMF, EU-WC, NDC, KDMF, VMF, Others

arrow
Antibody Engineering
Not Confirmed
USDMF CEP/COS JDMF EU-WC NDC KDMF VMF Others AUDIT
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Listed Suppliers

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01

Rusan Pharma

India
arrow
Antibody Engineering
Not Confirmed
  • fda
  • EDQM
  • WHO-GMP

Virtual BoothRusan Pharma: Over 30 years of specializing in the treatment of Addiction and Pain Management.

Flag India
Digital Content Digital Content

n-Butyl Cyanoacrylate

About the Company : Rusan Pharma is a fully integrated global pharmaceutical company specializing in the treatment of addiction & pain management. We manufacture & market a wide range of APIs & formul...

Rusan Pharma is a fully integrated global pharmaceutical company specializing in the treatment of addiction & pain management. We manufacture & market a wide range of APIs & formulations, in the area of controlled substances. Our facilities are GMP-approved by Health Canada, EU, TGA, ANVISA, PIC/S, WHO, Russia & SAHPRA. We have CEP approval for various APIs such as Buprenorphine, Fentanyl, Naltrexone, Methadone, Bisoprolol & we also manufacture Naloxone, Nalbuphine, Nalmefene, Apomorphine, Efflornithine & Sodium Oxybate. We also develop & manufacture various transdermal patches & long-acting formulations such as depot injections & Implants.
Rusan Pharma

02

FandaChem

China
Antibody Engineering
Not Confirmed
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FandaChem

China
arrow
Antibody Engineering
Not Confirmed

n-Butyl Cyanoacrylate

About the Company : FandaChem, headquartered in Hangzhou, China, is a reputable supplier and exporter of chemicals with a focus on delivering high-quality products. Our expertise lies in exporting a w...

FandaChem, headquartered in Hangzhou, China, is a reputable supplier and exporter of chemicals with a focus on delivering high-quality products. Our expertise lies in exporting a wide range of superior chemicals, specializing in areas such as agrochemicals, flavors, fragrances, pharmaceuticals, intermediates, paints, resins, plastics, surfactants, polymers, cosmetics, and more. Dedicated to being your dependable partner in China, FandaChem is devoted to offering top-notch products, competitive prices, and excellent service to meet the needs of our customers.
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03

J&H CHEM

China
Antibody Engineering
Not Confirmed
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J&H CHEM

China
arrow
Antibody Engineering
Not Confirmed

n-Butyl Cyanoacrylate

About the Company : J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Valu...

J&H CHEM is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products of chemicals, pharmaceuticals, and specialities. As a highly customer-oriented enterprise, we always believe "Customer first, service foremost", put forward innovation, continuously improve pipeline, integrate our broad range of products and services with our technical expertise, customise a competitive package to meet our customers' specific needs.
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