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Naluzotan

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INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

1INTERMEDIATES

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

0 DRUGS IN DEVELOPMENT

DRUG PRODUCT COMPOSITIONS

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USP

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US Patents

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Health Canada Patents

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Chemistry

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Also known as: 740873-06-7, Prx-00023, Naluzotan (free base), Lq54e5b4ew, Chembl209821, Unii-lq54e5b4ew

Molecular Formula

C₂₃H₃₈N₄O₃S

Molecular Weight

450.6 g/mol

InChI Key

SPWZXWDPAWDKQE-UHFFFAOYSA-N

FDA UNII

LQ54E5B4EW

1 2D Structure

Naluzotan

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

N-[3-[4-[4-(cyclohexylmethylsulfonylamino)butyl]piperazin-1-yl]phenyl]acetamide

2.1.2 InChI

InChI=1S/C23H38N4O3S/c1-20(28)25-22-10-7-11-23(18-22)27-16-14-26(15-17-27)13-6-5-12-24-31(29,30)19-21-8-3-2-4-9-21/h7,10-11,18,21,24H,2-6,8-9,12-17,19H2,1H3,(H,25,28)

2.1.3 InChI Key

SPWZXWDPAWDKQE-UHFFFAOYSA-N

2.1.4 Canonical SMILES

CC(=O)NC1=CC(=CC=C1)N2CCN(CC2)CCCCNS(=O)(=O)CC3CCCCC3

2.2 Other Identifiers

2.2.1 UNII

LQ54E5B4EW

2.3 Synonyms

2.3.1 MeSH Synonyms

1. N-(3-(4-(4-cyclohexylmethanesulfonylaminobutyl)piperazin-1-yl)phenyl)acetamide

2. Prx 00023

3. Prx-00023

4. Prx00023

2.3.2 Depositor-Supplied Synonyms

1. 740873-06-7

2. Prx-00023

3. Naluzotan (free Base)

4. Lq54e5b4ew

5. Chembl209821

6. Unii-lq54e5b4ew

7. Acetamide, N-(3-(4-(4-(((cyclohexylmethyl)sulfonyl)amino)butyl)-1-piperazinyl)phenyl)-

8. N-(3-(4-(4-(((cyclohexylmethyl)sulfonyl)amino)butyl)piperazin-1-yl)phenyl)acetamide

9. N-(3-(4-(4-((cyclohexylmethyl)sulfonamido)butyl)piperazin-1-yl)phenyl)acetamide

10. Naluzotan [usan]

11. Naluzotan [usan:inn]

12. N-(3-(4-(4-cyclohexylmethanesulfonylaminobutyl)piperazin-1-yl)phenyl)acetamide

13. N-(3-[4-(4-cyclohexylmethanesulfonylaminobutyl)piperazin-1-yl]phenyl)acetamide

14. N-[3-[4-[4-(cyclohexylmethylsulfonylamino)butyl]piperazin-1-yl]phenyl]acetamide

15. Prx 00023

16. Naluzotan [inn]

17. Naluzotan (usan/inn)

18. Schembl678016

19. Dtxsid40995527

20. Bcp20177

21. Prx00023

22. Zinc3963096

23. Bdbm50187377

24. Cs-6740

25. Db05562

26. Sb16847

27. Hy-14848

28. Db-115004

29. D09358

30. 833c676

31. L001689

32. Q6961039

33. N-(3-(4-(4-(cyclohexylmethylsulfonamido)butyl)piperazin-1-yl)phenyl)acetamide

34. N-[3-[4-[4-[(cyclohexylmethylsulfonyl)amino]butyl]piperazin-1-yl]phenyl]acetamide

35. N-{3-[4-(4-cyclohexylmethanesulfonylamino-butyl)-piperazin-1-yl]-phenyl}-acetamide

2.4 Create Date

2006-10-26

3 Chemical and Physical Properties

Molecular Formula	C₂₃H₃₈N₄O₃S
Molecular Weight	450.6 g/mol
XLogP3	3.2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	10
Exact Mass	450.26646226 g/mol
Monoisotopic Mass	450.26646226 g/mol
Topological Polar Surface Area	90.1 Å²
Heavy Atom Count	31
Formal Charge	0
Complexity	638
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

Investigated for use/treatment in anxiety disorders and depression.

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Serotonin 5-HT1 Receptor Agonists

Endogenous compounds and drugs that specifically stimulate SEROTONIN 5-HT1 RECEPTORS. Included under this heading are agonists for one or more of the specific 5-HT1 receptor subtypes. (See all compounds classified as Serotonin 5-HT1 Receptor Agonists.)

INTERMEDIATES SUPPLIERS

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ABOUT THIS PAGE

Naluzotan Manufacturers

A Naluzotan manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Naluzotan, including repackagers and relabelers. The FDA regulates Naluzotan manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Naluzotan API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Naluzotan Suppliers

A Naluzotan supplier is an individual or a company that provides Naluzotan active pharmaceutical ingredient (API) or Naluzotan finished formulations upon request. The Naluzotan suppliers may include Naluzotan API manufacturers, exporters, distributors and traders.

Naluzotan GMP

Naluzotan Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Naluzotan GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Naluzotan GMP manufacturer or Naluzotan GMP API supplier for your needs.

Naluzotan CoA

A Naluzotan CoA (Certificate of Analysis) is a formal document that attests to Naluzotan's compliance with Naluzotan specifications and serves as a tool for batch-level quality control.

Naluzotan CoA mostly includes findings from lab analyses of a specific batch. For each Naluzotan CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Naluzotan may be tested according to a variety of international standards, such as European Pharmacopoeia (Naluzotan EP), Naluzotan JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Naluzotan USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.