Find Naproxcinod manufacturers, exporters & distributors on PharmaCompass

Naproxcinod

Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

ACCESS ALL DATA
Browse all information
CHEMISTRY
Discover Molecule Insights

DEVELOPMENTS

2 Drugs in Development

2 Drugs in Development

INTERMEDIATES

1 Intermediates Suppliers

1 Intermediates Suppliers

DIGITAL CONTENT

17 NEWS #PharmaBuzz

media
17 NEWS #PharmaBuzz

Synopsis

ACTIVE PHARMA INGREDIENTS

API Suppliers

USDMF

CEP/COS

JDMF

EU WC

KDMF

NDC API

VMF

Listed Suppliers

API REF. PRICE (USD/KG)

$ 0

MARKET PLACE

API

FDF

FINISHED DOSAGE FORMULATIONS

FDF Dossiers

FDA Orange Book

Europe

Canada

Australia

South Africa

Listed Dossiers

DRUG PRODUCT COMPOSITIONS

REF. STANDARDS OR IMPURITIES

EDQM

USP

Others

PATENTS & EXCLUSIVITIES

US Patents

US Exclusivities

Health Canada Patents

DIGITAL CONTENT

Data Compilation #PharmaFlow

Stock Recap #PipelineProspector

Weekly News Recap #Phispers

News #PharmaBuzz

GLOBAL SALES INFORMATION

US Medicaid (USD)

Annual Reports (USD Million)

Finished Drug Prices

0RELATED EXCIPIENT COMPANIES

0EXCIPIENTS BY APPLICATIONS

Chemistry

Click the arrow to open the dropdown

Click the button for full data set

Also known as: 163133-43-5, Nitronaproxen, Naproxen-n-butyl nitrate, Hct 3012, Azd3582, No-naproxen

Molecular Formula

C₁₈H₂₁NO₆

Molecular Weight

347.4 g/mol

InChI Key

AKFJWRDCWYYTIG-ZDUSSCGKSA-N

FDA UNII

V24GR4LI3I

1 2D Structure

Naproxcinod

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

4-nitrooxybutyl (2S)-2-(6-methoxynaphthalen-2-yl)propanoate

2.1.2 InChI

InChI=1S/C18H21NO6/c1-13(18(20)24-9-3-4-10-25-19(21)22)14-5-6-16-12-17(23-2)8-7-15(16)11-14/h5-8,11-13H,3-4,9-10H2,1-2H3/t13-/m0/s1

2.1.3 InChI Key

AKFJWRDCWYYTIG-ZDUSSCGKSA-N

2.1.4 Canonical SMILES

CC(C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OCCCCO[N+](=O)[O-]

2.1.5 Isomeric SMILES

C[C@@H](C1=CC2=C(C=C1)C=C(C=C2)OC)C(=O)OCCCCO[N+](=O)[O-]

2.2 Other Identifiers

2.2.1 UNII

V24GR4LI3I

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 4-(nitrooxy)butyl-(2s)-2-(6-methoxy-2-naphthyl)propanoate

2. Azd 3582

3. Azd-3582

4. Azd3582

5. Naproxen-n-butyl Nitrate

6. Nicox

7. Nitric Oxide Naproxen

8. Nitric Oxide-releasing Naproxen

9. No-naproxen

2.3.2 Depositor-Supplied Synonyms

1. 163133-43-5

2. Nitronaproxen

3. Naproxen-n-butyl Nitrate

4. Hct 3012

5. Azd3582

6. No-naproxen

7. Azd-3582

8. Hct-3012

9. Ar-p900758xx

10. Azd 3582

11. V24gr4li3i

12. Chebi:76254

13. (s)-2-(6-methoxy-2-naphthyl)propanoic Acid 4-nitrooxybutyl Ester

14. 2-naphthaleneacetic Acid, 6-methoxy-alpha-methyl-, 4-(nitrooxy)butyl Ester, (alphas)-

15. 4-nitrooxybutyl (2s)-2-(6-methoxynaphthalen-2-yl)propanoate

16. 4-(nitrooxy)butyl (2s)-2-(6-methoxynaphthalen-2-yl)propanoate

17. 4-(nitrooxy)butyl (s)-2-(6-methoxynaphthalen-2-yl)propanoate

18. 4-(nitrooxy)butyl (2s)-2-(6-methoxy-2-naphthyl)propanoate

19. Naproxcinod [usan]

20. Naproxcinod [usan:inn]

21. Unii-v24gr4li3i

22. Naproxcinodum

23. Naproxcinod [mi]

24. Naproxcinod [inn]

25. Naproxcinod (usan/inn)

26. Naproxen Nitroxybutyl Ester

27. Naproxcinod [who-dd]

28. Gtpl9551

29. Schembl1170879

30. Chembl2103831

31. Dtxsid20167523

32. Zinc1541804

33. Akos015914063

34. Db06682

35. Me-0138

36. Zd-3582

37. Ac-23946

38. Hy-14931

39. Cs-0003642

40. D09568

41. E87348

42. Q3335996

43. 4-(nitrooxy)butyl(2s)-2-(6-methoxy-2-naphthyl)propanoate

44. 4-(nitrooxy)butyl-(2s)-2-(6-methoxy-2 Naphthyl)propanoate

45. (s)-2-(6-methoxy-2-naphtyl) Propionic Acid 4-nitrooxybutyl Ester

46. 2-naphthaleneacetic Acid, 6-methoxy-alpha-methyl-, 4-(nitrooxy)butyl Ester, (s)-

47. 2-naphthaleneacetic Acid, 6-methoxy-.alpha.-methyl-, 4-(nitrooxy)butyl Ester, (.alpha.s)-

2.4 Create Date

2006-10-25

3 Chemical and Physical Properties

Molecular Formula	C₁₈H₂₁NO₆
Molecular Weight	347.4 g/mol
XLogP3	4.1
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	6
Rotatable Bond Count	9
Exact Mass	347.13688739 g/mol
Monoisotopic Mass	347.13688739 g/mol
Topological Polar Surface Area	90.6 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	438
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Drug and Medication Information

4.1 Drug Indication

Investigated for use/treatment in pain (acute or chronic), inflammatory disorders (unspecified), osteoarthritis, and arthritis and arthritic pain.

Primary osteoarthritis

5 Pharmacology and Biochemistry

5.1 MeSH Pharmacological Classification

Nitric Oxide Donors

A diverse group of agents, with unique chemical structures and biochemical requirements, which generate NITRIC OXIDE. These compounds have been used in the treatment of cardiovascular diseases and the management of acute myocardial infarction, acute and chronic congestive heart failure, and surgical control of blood pressure. (Adv Pharmacol 1995;34:361-81) (See all compounds classified as Nitric Oxide Donors.)

5.2 ATC Code

M - Musculo-skeletal system

M01 - Antiinflammatory and antirheumatic products

M01A - Antiinflammatory and antirheumatic products, non-steroids

M01AE - Propionic acid derivatives

M01AE18 - Naproxcinod

Drugs in Development

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

INTERMEDIATES SUPPLIERS

FULL SCREEN VIEW Click here to open all results in a new tab [this preview display 10 results]

Digital Content

Create Content with PharmaCompass, ask us

NEWS #PharmaBuzz

ABOUT THIS PAGE

Naproxcinod Manufacturers

A Naproxcinod manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Naproxcinod, including repackagers and relabelers. The FDA regulates Naproxcinod manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Naproxcinod API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Naproxcinod Suppliers

A Naproxcinod supplier is an individual or a company that provides Naproxcinod active pharmaceutical ingredient (API) or Naproxcinod finished formulations upon request. The Naproxcinod suppliers may include Naproxcinod API manufacturers, exporters, distributors and traders.

Naproxcinod GMP

Naproxcinod Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Naproxcinod GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Naproxcinod GMP manufacturer or Naproxcinod GMP API supplier for your needs.

Naproxcinod CoA

A Naproxcinod CoA (Certificate of Analysis) is a formal document that attests to Naproxcinod's compliance with Naproxcinod specifications and serves as a tool for batch-level quality control.

Naproxcinod CoA mostly includes findings from lab analyses of a specific batch. For each Naproxcinod CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Naproxcinod may be tested according to a variety of international standards, such as European Pharmacopoeia (Naproxcinod EP), Naproxcinod JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Naproxcinod USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.