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1. 67555, R
2. Alpha,alpha'-(iminobis(methylene))bis(6-fluoro-3,4-dihydro)-2h-1-benzopyran-2-methanol
3. Bystolic
4. Hydrochloride, Nebivolol
5. Lobivon
6. Nebilet
7. Nebivolol
8. R 67555
9. R-67555
10. R67555
11. Silostar
1. 169293-50-9
2. Nebivolol Hcl
3. 2,2'-azanediylbis(1-(6-fluorochroman-2-yl)ethanol) Hydrochloride
4. 152520-56-4
5. Rac Nebivolol Hydrochloride
6. R 065824 Hydrochloride
7. Nebilox
8. Rac-nebivolol Hcl
9. R-067555
10. Schembl514784
11. N-phenyliminodiaceticacid
12. Chembl1201731
13. Akos016006035
14. Ac-4233
15. Ac-5636
16. Ccg-214847
17. Ro67555
18. As-12100
19. Cs-0362720
20. Ft-0652243
21. Ft-0655833
22. 520n564
23. W-60374
24. J-010524
25. 1-(6-fluoro-3,4-dihydro-2h-chromen-2-yl)-2-[[2-(6-fluoro-3,4-dihydro-2h-chromen-2-yl)-2-hydroxyethyl]amino]ethanol;hydrochloride
26. 2h-1-benzopyran-2-methanol,a,a'-[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-,hydrochloride(1:1)
27. Alpha,alpha'[iminobis(methylene)]bis[6-fluoro-3,4-dihydro-2h-1-benzopyran-2-methanol]hydrochloride
Molecular Weight | 441.9 g/mol |
---|---|
Molecular Formula | C22H26ClF2NO4 |
Hydrogen Bond Donor Count | 4 |
Hydrogen Bond Acceptor Count | 7 |
Rotatable Bond Count | 6 |
Exact Mass | 441.1518423 g/mol |
Monoisotopic Mass | 441.1518423 g/mol |
Topological Polar Surface Area | 71 Ų |
Heavy Atom Count | 30 |
Formal Charge | 0 |
Complexity | 483 |
Isotope Atom Count | 0 |
Defined Atom Stereocenter Count | 0 |
Undefined Atom Stereocenter Count | 4 |
Defined Bond Stereocenter Count | 0 |
Undefined Bond Stereocenter Count | 0 |
Covalently Bonded Unit Count | 2 |
Adrenergic beta-1 Receptor Agonists
Compounds that bind to and activate ADRENERGIC BETA-1 RECEPTORS. (See all compounds classified as Adrenergic beta-1 Receptor Agonists.)
Antihypertensive Agents
Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS. (See all compounds classified as Antihypertensive Agents.)
Vasodilator Agents
Drugs used to cause dilation of the blood vessels. (See all compounds classified as Vasodilator Agents.)
GDUFA
DMF Review : Complete
Rev. Date : 2014-03-25
Pay. Date : 2013-09-11
DMF Number : 21152
Submission : 2007-12-08
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2014-10-13
Pay. Date : 2014-10-06
DMF Number : 22735
Submission : 2009-03-31
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2013-04-04
Pay. Date : 2012-12-05
DMF Number : 25296
Submission : 2011-09-12
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2015-01-05
Pay. Date : 2014-10-07
DMF Number : 28627
Submission : 2014-09-10
Status : Active
Type : II
GDUFA
DMF Review : N/A
Rev. Date :
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DMF Number : 15417
Submission : 2001-05-07
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2016-10-21
Pay. Date : 2016-08-24
DMF Number : 29996
Submission : 2016-02-19
Status : Active
Type : II
GDUFA
DMF Review : Complete
Rev. Date : 2014-12-01
Pay. Date : 2014-11-20
DMF Number : 24916
Submission : 2011-05-04
Status : Active
Type : II
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DMF Number : 26343
Submission : 2012-08-21
Status : Inactive
Type : II
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DMF Number : 22906
Submission : 2009-06-29
Status : Active
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Rev. Date : 2016-04-13
Pay. Date : 2015-09-21
DMF Number : 29730
Submission : 2015-09-28
Status : Active
Type : II
Certificate Number : R0-CEP 2022-095 - Rev 00
Status : Valid
Issue Date : 2022-08-31
Type : Chemical
Substance Number : 2775
Certificate Number : R0-CEP 2021-403 - Rev 00
Status : Valid
Issue Date : 2022-07-06
Type : Chemical
Substance Number : 2775
Certificate Number : CEP 2023-063 - Rev 01
Status : Valid
Issue Date : 2024-07-30
Type : Chemical
Substance Number : 2775
Nebivolol hydrochloride, Crystalline
Certificate Number : CEP 2022-193 - Rev 01
Status : Valid
Issue Date : 2024-03-13
Type : Chemical
Substance Number : 2775
Certificate Number : CEP 2022-069 - Rev 00
Status : Valid
Issue Date : 2024-04-25
Type : Chemical
Substance Number : 2775
Certificate Number : CEP 2023-122 - Rev 00
Status : Valid
Issue Date : 2024-07-19
Type : Chemical
Substance Number : 2775
Certificate Number : R0-CEP 2022-170 - Rev 00
Status : Valid
Issue Date : 2022-12-09
Type : Chemical
Substance Number : 2775
Certificate Number : CEP 2022-140 - Rev 01
Status : Valid
Issue Date : 2023-12-20
Type : Chemical
Substance Number : 2775
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