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Polfa Tarchomin is a leading Polish pharmaceutical company with 200 year tradition in manufacture and sale of pharmaceutical products.

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Chemistry

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Also known as: 480-41-1, Salipurpol, Salipurol, (s)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one, (s)-naringenin, Pelargidanon

Molecular Formula

C₁₅H₁₂O₅

Molecular Weight

272.25 g/mol

InChI Key

FTVWIRXFELQLPI-ZDUSSCGKSA-N

FDA UNII

HN5425SBF2

naringenin is a natural product found in Elaeodendron croceum, Garcinia multiflora, and other organisms with data available.

1 2D Structure

Naringenin

2 Identification

2.1 Computed Descriptors

2.1.1 IUPAC Name

(2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

2.1.2 InChI

InChI=1S/C15H12O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-6,13,16-18H,7H2/t13-/m0/s1

2.1.3 InChI Key

FTVWIRXFELQLPI-ZDUSSCGKSA-N

2.1.4 Canonical SMILES

C1C(OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

2.1.5 Isomeric SMILES

C1[C@H](OC2=CC(=CC(=C2C1=O)O)O)C3=CC=C(C=C3)O

2.2 Other Identifiers

2.2.1 UNII

HN5425SBF2

2.3 Synonyms

2.3.1 MeSH Synonyms

1. 4',5,7-trihydroxyflavanone

2. Be 14348a

3. Be-14348a

4. Naringenin-7-sulfate

2.3.2 Depositor-Supplied Synonyms

1. 480-41-1

2. Salipurpol

3. Salipurol

4. (s)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

5. (s)-naringenin

6. Pelargidanon

7. (2s)-naringenin

8. Naringetol

9. Naringenine

10. Asahina

11. Nsc 11855

12. Ccris 5839

13. (-)-naringenin

14. Yso1

15. Nsc 34875

16. (-)-(2s)-naringenin

17. Chembl9352

18. (s)-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

19. Ai3-23355

20. Hn5425sbf2

21. Chebi:17846

22. Flavanone, 4',5,7-trihydroxy-

23. 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

24. 4h-1-benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2s)-

25. Narigenin

26. Nsc-11855

27. (2s)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4h-chromen-4-one

28. 5,7,4'-trihydroxyflavanone

29. (r,s)-naringenin

30. Sr-01000721771

31. (2s)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

32. Unii-hn5425sbf2

33. 2uxu

34. 4deu

35. S-dihydrogenistein

36. Einecs 207-550-2

37. Pelargidanon 1602

38. Spectrum_000247

39. 4eh3

40. Naringenin [mi]

41. Spectrum2_000325

42. Spectrum3_000567

43. Spectrum4_000124

44. Spectrum5_001423

45. Naringenin [inci]

46. 4',5,7-trioh-flavone

47. 4',5,7-trihydroxyflavanon

48. Naringenin, (-)-

49. Schembl20570

50. Bspbio_001954

51. Kbiogr_000508

52. Kbioss_000727

53. Mls000574861

54. Bidd:er0116

55. Divk1c_000118

56. Spectrum1500746

57. Spbio_000329

58. 4',5, 7-trihydroxyflavanone

59. 5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4h-chromen-4-one

60. Dtxsid1022392

61. Bdbm23419

62. Hms500f20

63. Kbio1_000118

64. Kbio2_000727

65. Kbio2_003295

66. Kbio2_005863

67. Kbio3_001454

68. 4h-1-benzopyran-4-one, 2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (s)-

69. Ninds_000118

70. (2s)-5,7,4'-trihydroxyflavone

71. Aids001417

72. Hms2202m06

73. Zinc156701

74. (2s)-4',5,7-trihydroxyflavanone

75. Hy-n0100

76. Tnp00287

77. (2s)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one

78. (s)-2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-4-benzopyrone

79. Ccg-38601

80. Lmpk12140001

81. Phytochemistry 8: 127 (1969)

82. S2394

83. (2s)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2h-1-benzopyran-4-one

84. Akos016843490

85. Cs-6421

86. Db03467

87. Fs-4072

88. Sdccgmls-0066570.p001

89. (2s)-4',5,7-trihydroxyflavan-4-one

90. Idi1_000118

91. Ncgc00016457-01

92. Ncgc00016457-02

93. Ncgc00016457-03

94. Ncgc00017346-01

95. Ncgc00163598-01

96. Ac-33954

97. Cas-480-41-1

98. Flavanone, 4',5,7-trihydroxy- (8ci)

99. Smr000156272

100. Ft-0617134

101. Sw219329-1

102. C00509

103. A827427

104. Q418374

105. Q-100666

106. Sr-01000721771-3

107. Sr-01000721771-4

108. 5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-chroman-4-one

109. Brd-k08832567-001-02-4

110. Brd-k08832567-001-06-5

111. (-)-(2s)-5,7-dihydroxy-2-(4-hydroxyphenyl)chroman-4-one

112. (s)-2,3-dihydo-5,7-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

113. 2,3-dihydro-5,6-dihydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

114. 4h-1-benzopyran-4-one,2,3-dihydro-5,7-dihydroxy-2-(4-hydroxyphenyl)-, (2s)-

115. 13308-00-4

2.4 Create Date

2004-09-16

3 Chemical and Physical Properties

Molecular Formula	C₁₅H₁₂O₅
Molecular Weight	272.25 g/mol
XLogP3	2.4
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	1
Exact Mass	272.06847348 g/mol
Monoisotopic Mass	272.06847348 g/mol
Topological Polar Surface Area	87 Å²
Heavy Atom Count	20
Formal Charge	0
Complexity	363
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently Bonded Unit Count	1

4 Pharmacology and Biochemistry

4.1 MeSH Pharmacological Classification

Estrogen Antagonists

Compounds which inhibit or antagonize the action or biosynthesis of estrogenic compounds. (See all compounds classified as Estrogen Antagonists.)

Anti-Ulcer Agents

Various agents with different action mechanisms used to treat or ameliorate PEPTIC ULCER or irritation of the gastrointestinal tract. This has included ANTIBIOTICS to treat HELICOBACTER INFECTIONS; HISTAMINE H2 ANTAGONISTS to reduce GASTRIC ACID secretion; and ANTACIDS for symptomatic relief. (See all compounds classified as Anti-Ulcer Agents.)

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ABOUT THIS PAGE

Naringenin Manufacturers

A Naringenin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Naringenin, including repackagers and relabelers. The FDA regulates Naringenin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Naringenin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

click here to find a list of Naringenin manufacturers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PhamaCompass.

Naringenin Suppliers

A Naringenin supplier is an individual or a company that provides Naringenin active pharmaceutical ingredient (API) or Naringenin finished formulations upon request. The Naringenin suppliers may include Naringenin API manufacturers, exporters, distributors and traders.

click here to find a list of Naringenin suppliers with USDMF, JDMF, KDMF, CEP, GMP, COA and API Price related information on PharmaCompass.

Naringenin GMP

Naringenin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Naringenin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Naringenin GMP manufacturer or Naringenin GMP API supplier for your needs.

Naringenin CoA

A Naringenin CoA (Certificate of Analysis) is a formal document that attests to Naringenin's compliance with Naringenin specifications and serves as a tool for batch-level quality control.

Naringenin CoA mostly includes findings from lab analyses of a specific batch. For each Naringenin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Naringenin may be tested according to a variety of international standards, such as European Pharmacopoeia (Naringenin EP), Naringenin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Naringenin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.