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Synopsis

ACTIVE PHARMA INGREDIENTS

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Chemistry

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Also known as: 14259-46-2, Isonaringin, Isonaringenin, Naringenin-7-o-rutinoside, Naringenin 7-o-rutinoside, (2s)-narirutin
Molecular Formula
C27H32O14
Molecular Weight
580.5  g/mol
InChI Key
HXTFHSYLYXVTHC-AJHDJQPGSA-N
FDA UNII
06M5EAT0YC

Narirutin
narirutin is a natural product found in Cyclopia subternata, Citrus latipes, and other organisms with data available.
1 2D Structure

Narirutin

2 Identification
2.1 Computed Descriptors
2.1.1 IUPAC Name
(2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one
2.1.2 InChI
InChI=1S/C27H32O14/c1-10-20(31)22(33)24(35)26(38-10)37-9-18-21(32)23(34)25(36)27(41-18)39-13-6-14(29)19-15(30)8-16(40-17(19)7-13)11-2-4-12(28)5-3-11/h2-7,10,16,18,20-29,31-36H,8-9H2,1H3/t10-,16-,18+,20-,21+,22+,23-,24+,25+,26+,27+/m0/s1
2.1.3 InChI Key
HXTFHSYLYXVTHC-AJHDJQPGSA-N
2.1.4 Canonical SMILES
CC1C(C(C(C(O1)OCC2C(C(C(C(O2)OC3=CC(=C4C(=O)CC(OC4=C3)C5=CC=C(C=C5)O)O)O)O)O)O)O)O
2.1.5 Isomeric SMILES
C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC=C(C=C5)O)O)O)O)O)O)O)O
2.2 Other Identifiers
2.2.1 UNII
06M5EAT0YC
2.3 Synonyms
2.3.1 Depositor-Supplied Synonyms

1. 14259-46-2

2. Isonaringin

3. Isonaringenin

4. Naringenin-7-o-rutinoside

5. Naringenin 7-o-rutinoside

6. (2s)-narirutin

7. Chebi:28705

8. 06m5eat0yc

9. (2s)-5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-3,4-dihydro-2h-chromen-7-yl 6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranoside

10. (s)-5-hydroxy-2-(4-hydroxyphenyl)-7-(((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-((((2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yl)oxy)methyl)tetrahydro-2h-pyran-2-yl)oxy)chroman-4-one

11. Mfcd00017316

12. Naringenin 7-beta-rutinoside

13. Fema No. 2769

14. Brovincaminefumarte

15. Einecs 238-138-0

16. Naringen

17. Naringin Extract (citrus Paradisi Macf.)

18. Narirutin [inci]

19. Unii-06m5eat0yc

20. Isonaringin [usp-rs]

21. Schembl669946

22. Chembl446246

23. Narirutin, >=98% (hplc)

24. Dtxsid30931535

25. Hy-n0804

26. Zinc8234300

27. Bdbm50249471

28. S9242

29. Naringenin 7.beta.-rutinoside

30. Akos030530132

31. Ccg-270129

32. (2s)-5-hydroxy-2-(4-hydroxyphenyl)-7-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-[[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one

33. As-75180

34. Cs-0009810

35. N1696

36. C09793

37. 259n462

38. Flavanone, 4',5,7-trihydroxy-, 7-beta-rutinoside

39. Q-100159

40. Q13569061

41. Flavanone, 4',5,7-trihydroxy-, 7.beta.-rutinoside

42. (2s)-5-hydroxy-2-(4-hydroxyphenyl)-7-{[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-({[(2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxy}methyl)oxan-2-yl]oxy}-3,4-dihydro-2h-1-benzopyran-4-one

43. (2s)-7-((6-o-(6-deoxy-.alpha.-l-mannopyranosyl)-.beta.-d-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

44. (s)-5-hydroxy-2-(4-hydroxyphenyl)-7-((2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(((2r,3r,4r,5r,6s)-3,4,5-trihydroxy-6-methyltetrahydro-2h-pyran-2-yloxy)methyl)tetrahydro-2h-pyran-2-yloxy)chroman-4-one

45. (s)-7-((6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-4h-1-benzopyran-4-one

46. 4h-1-benzopyran-4-one, 7-((6-o-(6-deoxy-.alpha.-l-mannopyranosyl)-.beta.-d-glucopyranosyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2s)-

47. 4h-1-benzopyran-4-one, 7-((6-o-(6-deoxy-alpha-l-mannopyranosyl)-beta-d-glucopyranoxyl)oxy)-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (s)-

48. 4h-1-benzopyran-4-one,7-[[6-o-(6-deoxy-a-l-mannopyranosyl)-b-d-glucopyranosyl]oxy]-2,3-dihydro-5-hydroxy-2-(4-hydroxyphenyl)-, (2s)-

2.4 Create Date
2005-06-24
3 Chemical and Physical Properties
Molecular Weight 580.5 g/mol
Molecular Formula C27H32O14
XLogP3-1.1
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count14
Rotatable Bond Count6
Exact Mass580.17920569 g/mol
Monoisotopic Mass580.17920569 g/mol
Topological Polar Surface Area225 Ų
Heavy Atom Count41
Formal Charge0
Complexity884
Isotope Atom Count0
Defined Atom Stereocenter Count11
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently Bonded Unit Count1

REF. STANDARDS & IMPURITIES

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ABOUT THIS PAGE

Narirutin Manufacturers

A Narirutin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Narirutin, including repackagers and relabelers. The FDA regulates Narirutin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Narirutin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.

Narirutin Suppliers

A Narirutin supplier is an individual or a company that provides Narirutin active pharmaceutical ingredient (API) or Narirutin finished formulations upon request. The Narirutin suppliers may include Narirutin API manufacturers, exporters, distributors and traders.

Narirutin GMP

Narirutin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.

GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).

PharmaCompass offers a list of Narirutin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Narirutin GMP manufacturer or Narirutin GMP API supplier for your needs.

Narirutin CoA

A Narirutin CoA (Certificate of Analysis) is a formal document that attests to Narirutin's compliance with Narirutin specifications and serves as a tool for batch-level quality control.

Narirutin CoA mostly includes findings from lab analyses of a specific batch. For each Narirutin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.

Narirutin may be tested according to a variety of international standards, such as European Pharmacopoeia (Narirutin EP), Narirutin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Narirutin USP).

Inform the supplier about your product requirements, specifying if you need a product with particular monograph like EP (Ph. Eur.), USP, JP, BP, or any other quality. In addition, clarify whether you need hydrochloride (HCl), anhydricum, base, micronisatum or a specific level of purity. To find reputable suppliers, utilize the filters and select those certified by GMP, FDA, or any other certification as per your requirement.
For your convenience, we have listed synonyms and CAS numbers to help you find the best supplier. The use of synonyms and CAS numbers can be helpful in identifying potential suppliers, but it is crucial to note that they might not always indicate the exact same product. It is important to confirm the product details with the supplier before making a purchase to ensure that it meets your requirements.
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