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1. 2-(5-(3-chlorophenyl)-6-(4-chlorophenyl)-1-(1-(isopropylsulfonyl)-3-methylbutan-2-yl)-3-methyl-2-oxopiperidin-3-yl)acetic Acid
2. Amg 232
1. Amg-232
2. 1352066-68-2
3. Amg 232
4. Amg232
5. Navtemadlin
6. Krt-232
7. Mdm2 Inhibitor Amg-232
8. Navtemadlin [usan]
9. 7r7g6eh5ul
10. Chembl3125702
11. 2-[(3r,5r,6s)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(2s)-3-methyl-1-propan-2-ylsulfonylbutan-2-yl]-2-oxopiperidin-3-yl]acetic Acid
12. Navtemadlin [inn]
13. Unii-7r7g6eh5ul
14. Krt232
15. Schembl9993310
16. Amg 232 [who-dd]
17. Gtpl11133
18. Dtxsid101025652
19. Bdbm50448947
20. Nsc781515
21. Nsc789723
22. Who 11546
23. Zinc103248035
24. Compound 2 [pmid: 24456472]
25. Cs-3282
26. Db15299
27. Nsc-781515
28. Nsc-789723
29. Ncgc00387801-04
30. Ncgc00387801-05
31. Ac-29027
32. As-17007
33. Hy-12296
34. A910091
35. (3r,5r,6s)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-((1s)-2-methyl-1-(((1-methylethyl)sulfonyl)methyl)propyl)-2-oxo-3-piperidineacetic Acid
36. {(3r,5r,6s)-5-(3-chlorophenyl)-6-(4-chlorophenyl)-3- Methyl-1-[(2s)-3-methyl-1-(propane-2-sulfonyl)butan2-yl]-2-oxopiperidin-3-yl}acetic Acid
37. 1447813-21-9
38. 3-iperidineacetic Acid, 5-(3-hlorophenyl)-6-(4-hlorophenyl)-3-ethyl-1-(1s)-2-ethyl-1-[(1-ethylethyl)ulfonyl]ethyl]ropyl]-2-xo-, (3r,5r,6s)-
39. 3-piperidineacetic Acid, 5-(3-chlorophenyl)-6-(4-chlorophenyl)-3-methyl-1-[(1s)-2-methyl-1-[[(1-methylethyl)sulfonyl]methyl]propyl]-2-oxo-, (3r,5r,6s)-
| Molecular Weight | 568.6 g/mol |
|---|---|
| Molecular Formula | C28H35Cl2NO5S |
| XLogP3 | 5.8 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 9 |
| Exact Mass | 567.1612998 g/mol |
| Monoisotopic Mass | 567.1612998 g/mol |
| Topological Polar Surface Area | 100 Ų |
| Heavy Atom Count | 37 |
| Formal Charge | 0 |
| Complexity | 912 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 4 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently Bonded Unit Count | 1 |
Drugs in Development
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A Navtemadlin manufacturer is defined as any person or entity involved in the manufacture, preparation, processing, compounding or propagation of Navtemadlin, including repackagers and relabelers. The FDA regulates Navtemadlin manufacturers to ensure that their products comply with relevant laws and regulations and are safe and effective to use. Navtemadlin API Manufacturers are required to adhere to Good Manufacturing Practices (GMP) to ensure that their products are consistently manufactured to meet established quality criteria.
A Navtemadlin supplier is an individual or a company that provides Navtemadlin active pharmaceutical ingredient (API) or Navtemadlin finished formulations upon request. The Navtemadlin suppliers may include Navtemadlin API manufacturers, exporters, distributors and traders.
Navtemadlin Active pharmaceutical ingredient (API) is produced in GMP-certified manufacturing facility.
GMP stands for Good Manufacturing Practices, which is a system used in the pharmaceutical industry to make sure that goods are regularly produced and monitored in accordance with quality standards. The FDA’s current Good Manufacturing Practices requirements are referred to as cGMP or current GMP which indicates that the company follows the most recent GMP specifications. The World Health Organization (WHO) has its own set of GMP guidelines, called the WHO GMP. Different countries can also set their own guidelines for GMP like China (Chinese GMP) or the EU (EU GMP).
PharmaCompass offers a list of Navtemadlin GMP manufacturers, exporters & distributors, which can be sorted by USDMF, JDMF, KDMF, CEP (COS), WC, API price, and more, enabling you to easily find the right Navtemadlin GMP manufacturer or Navtemadlin GMP API supplier for your needs.
A Navtemadlin CoA (Certificate of Analysis) is a formal document that attests to Navtemadlin's compliance with Navtemadlin specifications and serves as a tool for batch-level quality control.
Navtemadlin CoA mostly includes findings from lab analyses of a specific batch. For each Navtemadlin CoA document that a company creates, the USFDA specifies specific requirements, such as supplier information, material identification, transportation data, evidence of conformity and signature data.
Navtemadlin may be tested according to a variety of international standards, such as European Pharmacopoeia (Navtemadlin EP), Navtemadlin JP (Japanese Pharmacopeia) and the US Pharmacopoeia (Navtemadlin USP).
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